Register | Sign In


Understanding through Discussion


EvC Forum active members: 63 (9161 total)
2 online now:
Newest Member: popoi
Post Volume: Total: 915,581 Year: 2,838/9,624 Month: 683/1,588 Week: 89/229 Day: 61/28 Hour: 0/3


Thread  Details

Email This Thread
Newer Topic | Older Topic
  
Author Topic:   Evolution is True Because Life Needs It
Taq
Member
Posts: 9944
Joined: 03-06-2009
Member Rating: 4.8


(1)
Message 111 of 188 (653560)
02-22-2012 3:14 PM
Reply to: Message 110 by RAZD
02-22-2012 2:51 PM


Re: ... yet there are new breeds of dog ...
These are new variations within the dog clade, and it seems the process of mutation and variation is still operating. Certainly these new breeds have added to the diversity of dogs.
This is most certainly true. A good example are dachsunds. They carry a mutation in their FGRF3 gene causing them to have stunted limbs, otherwise known as achondroplasia. Humans with mutations in the homologous gene also have achondroplasia (i.e. dwarfism). This is a dominant trait meaning that you only need one copy of the gene in order to have the condition. Obviously, this mutation could not have come from their wolf ancestors. Instead, this trait was isolated and bred to homozygosity by breeders after the mutation occurred in their breeding stocks.

This message is a reply to:
 Message 110 by RAZD, posted 02-22-2012 2:51 PM RAZD has seen this message but not replied

  
Taq
Member
Posts: 9944
Joined: 03-06-2009
Member Rating: 4.8


Message 188 of 188 (671635)
08-28-2012 3:52 PM
Reply to: Message 183 by foreveryoung
08-26-2012 11:37 PM


Re: Silly creationist story
When you multiply the size of the human genome by the mutation rate per site per generation you get 35 mutations per genome per generation. How many cell divisions occur in one spot in the human body in a 20 year generation? If it is significantly greater than 35 than you don't have a mutation roughly occurring everytime a cell divides. For example if one spot in the body has cell division occurring 3500 times in a 20 year period, you have mutations occurring one time in every 100 cell divisions.
"Here we present, to our knowledge, the first direct comparative analysis of male and female germline mutation rates from the complete genome sequences of two parent-offspring trios. Through extensive validation, we identified 49 and 35 germline de novo mutations (DNMs) in two trio offspring, as well as 1,586 non-germline DNMs arising either somatically or in the cell lines from which the DNA was derived."
Europe PMC
I think it would also be safe to say that you could find more mutations by increasing the tissue types you are sequencing, as well as the age of the donor. However, it doesn't appear to be a crazy number, like 1 million or so somatic mutations.
Edited by Taq, : No reason given.

This message is a reply to:
 Message 183 by foreveryoung, posted 08-26-2012 11:37 PM foreveryoung has seen this message but not replied

  
Newer Topic | Older Topic
Jump to:


Copyright 2001-2023 by EvC Forum, All Rights Reserved

™ Version 4.2
Innovative software from Qwixotic © 2024