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Author Topic:   Ratio of Deleterious Mutations to Beneficial Ones
Faith 
Suspended Member (Idle past 1470 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 20 of 35 (719381)
02-13-2014 7:56 PM
Reply to: Message 15 by NoNukes
02-13-2014 5:11 PM


The fact is that most human mutations are somewhere close to neutral with respect to fitness. We know this because every human has mutations. It may be that most mutations that have some significant fitness impact are deleterious rather than beneficial, but given that such mutations are selected against, I would expect that even lop sided ratios of deleterious vs beneficial mutations would not stop the process of evolution.
Are you talking about the kinds of mutations that occur in the body but not the reproductive cells or both or what?
How are they selected against?
ABE: Since we're all guessing, my guess would be that in some sense the vast majority are deleterious but not severe enough to be selected against and those mutations are going to get passed on along with all the other alleles, and any deleterious effects are going to show up generations later.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.

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Replies to this message:
 Message 23 by NosyNed, posted 02-13-2014 8:26 PM Faith has replied
 Message 24 by NoNukes, posted 02-13-2014 10:02 PM Faith has replied

  
Faith 
Suspended Member (Idle past 1470 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 21 of 35 (719382)
02-13-2014 8:01 PM
Reply to: Message 19 by Taq
02-13-2014 6:50 PM


Re: Neutral -- maybe not
It's all guesswork, isn't it? Seems to me I've seen threads where it's been affirmed by evolutionists that the vast majority of mutations are deleterious, and I've seen everything else. Estimate this, estimate that. You guys really don't know.

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 Message 19 by Taq, posted 02-13-2014 6:50 PM Taq has replied

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Faith 
Suspended Member (Idle past 1470 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 25 of 35 (719397)
02-13-2014 10:10 PM
Reply to: Message 24 by NoNukes
02-13-2014 10:02 PM


By miscarriage I guess?

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Faith 
Suspended Member (Idle past 1470 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 26 of 35 (719398)
02-13-2014 10:13 PM
Reply to: Message 23 by NosyNed
02-13-2014 8:26 PM


Re: Selected against
The problem is that many deleterious mutations are NOT selected out; they produce genetic disease that a person may simply have to live with. If the disease is horrible enough then the person will suffer for years and eventually die of it. Is that what is meant by "selection?"

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Faith 
Suspended Member (Idle past 1470 days)
Posts: 35298
From: Nevada, USA
Joined: 10-06-2001


Message 28 of 35 (719426)
02-14-2014 12:09 AM
Reply to: Message 27 by dwise1
02-13-2014 11:53 PM


Re: Neutral -- maybe not
I use the basic concepts, not the mathematics, and I'm not interested in learning any of the sciences to that extent, it would just be a waste of time. I take what makes sense on my model.
ABE: But since you changed the subject, let me repeat the post you were ostensibly answering but didn't:
It's all guesswork, isn't it? Seems to me I've seen threads where it's been affirmed by evolutionists that the vast majority of mutations are deleterious, and I've seen everything else. Estimate this, estimate that. You guys really don't know.
Lotta guesswork, nothing really solid is known about mutations.
Edited by Faith, : No reason given.
Edited by Faith, : No reason given.

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Replies to this message:
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