Register | Sign In


Understanding through Discussion


EvC Forum active members: 64 (9164 total)
4 online now:
Newest Member: ChatGPT
Post Volume: Total: 916,834 Year: 4,091/9,624 Month: 962/974 Week: 289/286 Day: 10/40 Hour: 1/0


Thread  Details

Email This Thread
Newer Topic | Older Topic
  
Author Topic:   Haldane's 1957 Paper, "The Cost Of Selection"
Percy
Member
Posts: 22499
From: New Hampshire
Joined: 12-23-2000
Member Rating: 4.9


Message 7 of 12 (728198)
05-25-2014 8:32 AM
Reply to: Message 5 by GarretKadeDupre
05-24-2014 10:16 PM


GarretkadeDupre writes:
Would someone else please help me here? I've read the paper through more than once. I've been told that Haldane does in fact account for sexual recombination in his paper, but I don't see where or how.
Just poking around on the Internet I found this over at the Wikipedia article on Haldane's Dilemma:
Wikipedia writes:
Haldane stated at the time of publication "I am quite aware that my conclusions will probably need drastic revision", and subsequent corrected calculations found that the cost disappears. He had made an invalid simplifying assumption which negated his assumption of constant population size, and had also incorrectly assumed that two mutations would take twice as long to reach fixation as one, while sexual recombination means that two can be selected simultaneously so that both reach fixation more quickly.
So it looks like the answer is no, Haldane did not account for sexual recombination.
--Percy

This message is a reply to:
 Message 5 by GarretKadeDupre, posted 05-24-2014 10:16 PM GarretKadeDupre has not replied

  
Newer Topic | Older Topic
Jump to:


Copyright 2001-2023 by EvC Forum, All Rights Reserved

™ Version 4.2
Innovative software from Qwixotic © 2024