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Author Topic:   How do you define the word Evolution?
RAZD
Member (Idle past 1405 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 916 of 936 (814261)
07-05-2017 1:26 PM
Reply to: Message 913 by Taq
07-05-2017 12:45 PM


Re: Polyploidy -- evolution by doubling the genome
Before mutations: 100% brown allele
After mutations: 10% black fur, 90% brown fur
You are saying that after the mutations there is less genetic diversity?
And ... black is dominant ... so, the Hardy-Weinberg equation gives us:
p^2 + 2pq + q^2
where p is one allele and q the other allele, so pq is heterozygous and the others are homozygous,
The equation with {br} = 0.9 (making {BL} = .01) is
(0.9)^2 + 2(0.9)(0.1) + (0.1)^2
= 0.81 + 0.18 + 0.01
and 81% are tan (homozygous) while 19% are black (1% homozygous and 18% heterozygous)
and ~1 in 5 mice can utilize the lava bed habitat, and of those ~1 in 4 offspring will be tan and need to escape back to the tan soil habitat.
Enjoy

we are limited in our ability to understand
by our ability to understand
RebelAmerican☆Zen☯Deist
... to learn ... to think ... to live ... to laugh ...
to share.


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This message is a reply to:
 Message 913 by Taq, posted 07-05-2017 12:45 PM Taq has replied

Replies to this message:
 Message 917 by Taq, posted 07-05-2017 3:10 PM RAZD has replied
 Message 921 by CRR, posted 07-06-2017 6:59 PM RAZD has seen this message but not replied
 Message 924 by caffeine, posted 07-07-2017 1:53 PM RAZD has replied

  
Taq
Member
Posts: 9973
Joined: 03-06-2009
Member Rating: 5.7


(1)
Message 917 of 936 (814273)
07-05-2017 3:10 PM
Reply to: Message 916 by RAZD
07-05-2017 1:26 PM


Re: Polyploidy -- evolution by doubling the genome
RAZD writes:
And ... black is dominant ... so, the Hardy-Weinberg equation gives us:
That was more of a guesstimate. The actual number is probably a bit lower since the black basalt outcroppings make up a small percentage of their overall range.
Edited by Taq, : No reason given.

This message is a reply to:
 Message 916 by RAZD, posted 07-05-2017 1:26 PM RAZD has replied

Replies to this message:
 Message 918 by RAZD, posted 07-06-2017 6:10 AM Taq has replied

  
RAZD
Member (Idle past 1405 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 918 of 936 (814303)
07-06-2017 6:10 AM
Reply to: Message 917 by Taq
07-05-2017 3:10 PM


SRe: Polyploidy -- evolution by doubling the genome
So 90% of statistics used in arguments are made up on the spot?

we are limited in our ability to understand
by our ability to understand
RebelAmerican☆Zen☯Deist
... to learn ... to think ... to live ... to laugh ...
to share.


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This message is a reply to:
 Message 917 by Taq, posted 07-05-2017 3:10 PM Taq has replied

Replies to this message:
 Message 919 by Pressie, posted 07-06-2017 8:11 AM RAZD has seen this message but not replied
 Message 923 by Taq, posted 07-07-2017 10:59 AM RAZD has seen this message but not replied

  
Pressie
Member
Posts: 2103
From: Pretoria, SA
Joined: 06-18-2010


(1)
Message 919 of 936 (814312)
07-06-2017 8:11 AM
Reply to: Message 918 by RAZD
07-06-2017 6:10 AM


Re: SRe: Polyploidy -- evolution by doubling the genome
RAZD writes:
So 90% of statistics used in arguments are made up on the spot?
Not all. At the Uni I'm involved in around 80% of all the students who start studying Chemistry 1 don't even get basic degrees at the end. That's been relatively constant for around 100 years. So, when I look at the first year fresh faces trying chemistry 1 on the first day, I can tell them that around 80% of them won't ever get a degree. I ask them to study, study, study and change the stats.
Stats are not always useless. It just prepares people for reality.
Edited by Pressie, : No reason given.

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CRR
Member (Idle past 2243 days)
Posts: 579
From: Australia
Joined: 10-19-2016


Message 920 of 936 (814329)
07-06-2017 6:49 PM
Reply to: Message 870 by Taq
06-30-2017 11:56 AM


Re: MC1R gene and the agouti-signaling protein
"In the laboratory mouse, loss-of-function mutations at Mc1r are recessive and result in light color, whereas gain-of-function alleles are dominant and result in dark color (16)."
I was talking about loss of function between the MC1R gene and the agouti-signaling protein.
They are talking gain/loss of function as it relates to coat colour..
Dominant/recessive does not determine gain/loss of functional information. A normal light switch can be turned on or off. A broken light switch can result in a light permanently on (dominant) or permanently off (recessive); but the switch is broken in either case. Similarly with the MC1R gene.
Edited by CRR, : Changed subtitle

This message is a reply to:
 Message 870 by Taq, posted 06-30-2017 11:56 AM Taq has replied

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CRR
Member (Idle past 2243 days)
Posts: 579
From: Australia
Joined: 10-19-2016


(1)
Message 921 of 936 (814330)
07-06-2017 6:59 PM
Reply to: Message 916 by RAZD
07-05-2017 1:26 PM


Re: Hardy-Weinberg
and ~1 in 5 mice can utilize the lava bed habitat, and of those ~1 in 4 offspring will be tan and need to escape back to the tan soil habitat.
They probably should be considered as two separate populations with gene flow between them.

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Taq
Member
Posts: 9973
Joined: 03-06-2009
Member Rating: 5.7


(1)
Message 922 of 936 (814345)
07-07-2017 10:58 AM
Reply to: Message 920 by CRR
07-06-2017 6:49 PM


Re: MC1R gene and the agouti-signaling protein
CRR writes:
I was talking about loss of function between the MC1R gene and the agouti-signaling protein.
They are talking gain/loss of function as it relates to coat colour..
Dominant/recessive does not determine gain/loss of functional information. A normal light switch can be turned on or off. A broken light switch can result in a light permanently on (dominant) or permanently off (recessive); but the switch is broken in either case. Similarly with the MC1R gene.
You are claiming that any change, no matter what it is, is a broken switch. That is just denial.

This message is a reply to:
 Message 920 by CRR, posted 07-06-2017 6:49 PM CRR has not replied

  
Taq
Member
Posts: 9973
Joined: 03-06-2009
Member Rating: 5.7


(1)
Message 923 of 936 (814346)
07-07-2017 10:59 AM
Reply to: Message 918 by RAZD
07-06-2017 6:10 AM


Re: SRe: Polyploidy -- evolution by doubling the genome
RAZD writes:
So 90% of statistics used in arguments are made up on the spot?
+/- 1.8%. Don't forget the standard deviation.

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 Message 918 by RAZD, posted 07-06-2017 6:10 AM RAZD has seen this message but not replied

  
caffeine
Member (Idle past 1025 days)
Posts: 1800
From: Prague, Czech Republic
Joined: 10-22-2008


Message 924 of 936 (814354)
07-07-2017 1:53 PM
Reply to: Message 916 by RAZD
07-05-2017 1:26 PM


Re: Polyploidy -- evolution by doubling the genome
And ... black is dominant ... so, the Hardy-Weinberg equation gives us:
The alleles should only be expected to be in Hardy-Weinberg equilibrium in the absence of selection. Since both phenotypes are under selection, it's not relevant. The proportions will depend on the extent of the habitats that select for each colour morph.

This message is a reply to:
 Message 916 by RAZD, posted 07-05-2017 1:26 PM RAZD has replied

Replies to this message:
 Message 925 by RAZD, posted 07-07-2017 7:37 PM caffeine has seen this message but not replied
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RAZD
Member (Idle past 1405 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 925 of 936 (814356)
07-07-2017 7:37 PM
Reply to: Message 924 by caffeine
07-07-2017 1:53 PM


Re: Polyploidy -- evolution by doubling the genome
Guess I gots some readin to do.
Thanks

we are limited in our ability to understand
by our ability to understand
RebelAmerican☆Zen☯Deist
... to learn ... to think ... to live ... to laugh ...
to share.


Join the effort to solve medical problems, AIDS/HIV, Cancer and more with Team EvC! (click)

This message is a reply to:
 Message 924 by caffeine, posted 07-07-2017 1:53 PM caffeine has seen this message but not replied

Replies to this message:
 Message 926 by dwise1, posted 07-08-2017 12:17 AM RAZD has replied

  
dwise1
Member
Posts: 5930
Joined: 05-02-2006
Member Rating: 5.8


(1)
Message 926 of 936 (814357)
07-08-2017 12:17 AM
Reply to: Message 925 by RAZD
07-07-2017 7:37 PM


Re: Polyploidy -- evolution by doubling the genome
Same here. Like when I retire at the end of the year.
At many colleges and universities in the USA we have the Osher Lifelong Learning Institutes (OLLI) program for adults 50+. They draw on the members' own expertise for their own classes and special lectures, plus members get buy parking on campus and are usually able to audit the regular university courses. However, locally all the OLLI courses and lectures are during regular work hours, so you pretty much have to be retired to participate.
So I see auditing a population genetics course in my future ...

This message is a reply to:
 Message 925 by RAZD, posted 07-07-2017 7:37 PM RAZD has replied

Replies to this message:
 Message 927 by Coyote, posted 07-08-2017 12:35 AM dwise1 has replied
 Message 929 by RAZD, posted 07-08-2017 8:50 AM dwise1 has not replied

  
Coyote
Member (Idle past 2106 days)
Posts: 6117
Joined: 01-12-2008


Message 927 of 936 (814358)
07-08-2017 12:35 AM
Reply to: Message 926 by dwise1
07-08-2017 12:17 AM


Re: Polyploidy -- evolution by doubling the genome
...we have the Osher Lifelong Learning Institutes (OLLI) program for adults 50+
Good program! I've lectured there perhaps 10 times over the years.

Religious belief does not constitute scientific evidence, nor does it convey scientific knowledge.
Belief gets in the way of learning--Robert A. Heinlein
In the name of diversity, college student demands to be kept in ignorance of the culture that made diversity a value--StultisTheFool
It's not what we don't know that hurts, it's what we know that ain't so--Will Rogers
If I am entitled to something, someone else is obliged to pay--Jerry Pournelle
If a religion's teachings are true, then it should have nothing to fear from science...--dwise1
"Multiculturalism" demands that the US be tolerant of everything except its own past, culture, traditions, and identity.
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This message is a reply to:
 Message 926 by dwise1, posted 07-08-2017 12:17 AM dwise1 has replied

Replies to this message:
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dwise1
Member
Posts: 5930
Joined: 05-02-2006
Member Rating: 5.8


Message 928 of 936 (814360)
07-08-2017 1:38 AM
Reply to: Message 927 by Coyote
07-08-2017 12:35 AM


Re: Polyploidy -- evolution by doubling the genome
One of the main problems I'm faced with right now is ready access to research materials, given my work schedule. That will give me ready access to materials in the libraries.

This message is a reply to:
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RAZD
Member (Idle past 1405 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


(1)
Message 929 of 936 (814369)
07-08-2017 8:50 AM
Reply to: Message 926 by dwise1
07-08-2017 12:17 AM


Re: Polyploidy -- evolution by doubling the genome
So I see auditing a population genetics course in my future ...
I've been thinking of doing this too, especially as Brown University is a bicycle ride away and I could catch a lecture by Kenneth R. Miller.
Enjoy

we are limited in our ability to understand
by our ability to understand
RebelAmerican☆Zen☯Deist
... to learn ... to think ... to live ... to laugh ...
to share.


Join the effort to solve medical problems, AIDS/HIV, Cancer and more with Team EvC! (click)

This message is a reply to:
 Message 926 by dwise1, posted 07-08-2017 12:17 AM dwise1 has not replied

  
CRR
Member (Idle past 2243 days)
Posts: 579
From: Australia
Joined: 10-19-2016


Message 930 of 936 (815169)
07-17-2017 6:23 AM
Reply to: Message 924 by caffeine
07-07-2017 1:53 PM


Re: Hardy-Weinberg
caffeine writes:
The alleles should only be expected to be in Hardy-Weinberg equilibrium in the absence of selection.
Not quite. The population will still be subject to the same selection forces even after it has adapted to the environment, however these will tend to stabilise the population rather than change it.
Since both phenotypes are under selection..
Both population groups will move towards equilibrium for their environment, which is why for H-W Equilibrium they should be considered as separate groups. However since the groups interact where the habitats meet there will also be gene flow between the two which will interfere with equilibrium being reached.
Edited by CRR, : Changed subtitle

This message is a reply to:
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