I think that the problem is that ID has very little substance - there is no equivalent to evolutionary theory, just rather vague ideas which are not even generally accepted in the ID community and are in great need of development (at best).
But here's one. If Dembski could produce a genuine rigorous demonstration of at least one example of his CSI in biology then he would have a good case. I am firmly of the opinion that such a demonstration is impractical but Dembski claims to have a useful method that can be applied to biology. So let him do it - properly.