Register | Sign In


Understanding through Discussion


EvC Forum active members: 65 (9162 total)
1 online now:
Newest Member: popoi
Post Volume: Total: 915,819 Year: 3,076/9,624 Month: 921/1,588 Week: 104/223 Day: 2/13 Hour: 0/1


Thread  Details

Email This Thread
Newer Topic | Older Topic
  
Author Topic:   Random DNA Sequences Contain Information
caffeine
Member (Idle past 1025 days)
Posts: 1800
From: Prague, Czech Republic
Joined: 10-22-2008


Message 6 of 18 (815606)
07-21-2017 3:16 PM
Reply to: Message 5 by AnswersInGenitals
07-20-2017 5:21 PM


Re: If You Can Raed Tihs, You Msut Be Raelly Smrat
These results still seem surprising to me. Robustness through redundancy is the reason people always say most mutations are neutral with respect to fitness. Due to the redundancies in the genetic code, a lot of mutations don't have any phenotypic effect.
In this case they're not just claiming their random variants were harmless due to inbuilt redundancies - a quarter of them were actually fitter than the originals. That's surprising to me.

This message is a reply to:
 Message 5 by AnswersInGenitals, posted 07-20-2017 5:21 PM AnswersInGenitals has not replied

Replies to this message:
 Message 7 by Taq, posted 07-21-2017 3:19 PM caffeine has replied

  
caffeine
Member (Idle past 1025 days)
Posts: 1800
From: Prague, Czech Republic
Joined: 10-22-2008


Message 8 of 18 (815608)
07-21-2017 3:25 PM
Reply to: Message 7 by Taq
07-21-2017 3:19 PM


Re: If You Can Raed Tihs, You Msut Be Raelly Smrat
There are no "originals" in this experiment since they are random 150 base pair DNA segments bookended by a promoter and terminator.
I thought these were inserted into bacterial genomes and then the resulting bacteria competed against wild-type individuals. Did I misunderstand the abstract?

This message is a reply to:
 Message 7 by Taq, posted 07-21-2017 3:19 PM Taq has replied

Replies to this message:
 Message 9 by Taq, posted 07-21-2017 3:32 PM caffeine has seen this message but not replied
 Message 11 by Dr Jack, posted 07-22-2017 10:00 AM caffeine has seen this message but not replied

  
Newer Topic | Older Topic
Jump to:


Copyright 2001-2023 by EvC Forum, All Rights Reserved

™ Version 4.2
Innovative software from Qwixotic © 2024