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Author Topic:   Potential falsifications of the theory of evolution
shadow71
Member (Idle past 2959 days)
Posts: 706
From: Joliet, il, USA
Joined: 08-31-2010


Message 541 of 968 (601460)
01-20-2011 5:13 PM
Reply to: Message 540 by Granny Magda
01-20-2011 4:48 PM


Re: The past five decades of research in genetics and molecular biology have brouRe: yawn
Shadow wrote:
On this board the possibility of a non-Darwinian theory is never considered. Those who bring up the possibility are "uneducated".
Granny Magda writes;
Oh grow up and drop the martyr complex. I wasn't accusing you of being undereducated, I was suggesting that you were mistaken, You are being over-sensitive.
Granny I was referring to Razd in one of his prior posts, not you.
Will get back to you later in reply to your complete post.

This message is a reply to:
 Message 540 by Granny Magda, posted 01-20-2011 4:48 PM Granny Magda has seen this message but not replied

molbiogirl
Member (Idle past 2667 days)
Posts: 1909
From: MO
Joined: 06-06-2007


Message 542 of 968 (601462)
01-20-2011 5:33 PM
Reply to: Message 538 by shadow71
01-20-2011 3:47 PM


Re: Shapiro's use of the word "intelligent"
Sorry for the misunderstanding.
Yes, the quote I provided is a summary of Shapiro's position by someone other than Shapiro.
And yes. There is someone on talkrational who agrees with you, shadow.
However. It is clear from both the article and the presentation that Shapiro is using the term "intelligent" as it is used in information science.
He states that explicitly in the conclusion of his 1997 Boston Review article, A Third Way (Alternatives to Creationism and Darwinism)!
http://www.shapiro.bsd.uchicago.edu/...view1997.ThirdWay.pdf
Shapiro writes:
What significance does an emerging interface between biology and information science hold for thinking about evolution? ... Is there any guiding intelligence at work in the origin of species displaying exquisite adaptations that range from lambda prophage repression and the Krebs cycle through the mitotic apparatus and the eye to the immune system, mimicry, and social organization? Borrowing concepts from information science, new schools of evolutionists can begin to rephrase virtually intractable global questions in terms amenable to computer modelling and experimentation.
Emphasis added.
In addition, the title of Shapiro's presentation is A signal-responsive (cognitive) systems view of the genome.
Cognitive systems view of the genome, shadow. Not "intelligently designed genome".
ABE:
Here's another .pdf (from a 2006 talk Shapiro gave) where Shapiro uses "intelligence", "cognition" and "sentience" to refer to sophisticated mechanisms for intercellular communication:
http://www.shapiro.bsd.uchicago.edu/2006.ExeterMeeting.pdf
From the introduction:
Shapiro writes:
This remarkable series of observations requires us to revise basic ideas about biological information processing and recognize that even the smallest cells are sentient beings.
Emphasis added.
From the last paragraph:
Shapiro writes:
The take-home lesson of more than half a century of molecular microbiology is to recognize that bacterial information processing is far more powerful than human technology. The selected examples of bacterial smarts I have given show convincingly that these small cells are incredibly sophisticated at coordinating processes involving millions of individual events and at making them precise and reliable. In addition, the astonishing versatility and mastery bacteria display in managing the biosphere’s geochemical and thermodynamic transformations indicates that we have a great deal to learn about chemistry, physics and evolution from our small, but very intelligent, prokaryotic relatives.
Emphasis again added.
Edited by molbiogirl, : No reason given.

This message is a reply to:
 Message 538 by shadow71, posted 01-20-2011 3:47 PM shadow71 has replied

Replies to this message:
 Message 555 by shadow71, posted 01-20-2011 8:55 PM molbiogirl has replied
 Message 558 by Percy, posted 01-21-2011 7:02 AM molbiogirl has not replied

Taq
Member
Posts: 10072
Joined: 03-06-2009
Member Rating: 5.2


Message 543 of 968 (601465)
01-20-2011 6:16 PM
Reply to: Message 529 by shadow71
01-19-2011 5:22 PM


"Cell mergers and WGDs are the kinds of events that activate mobile DNA and genome restructuring. In order to fully integrate the genomic findings with our knowledge of mobile DNA, we have to make use of information about the molecular regulation of mobile DNA activities as well as McClintocks's view that cells RESPOND TO SIGNS OF DANGER, FREQUENTLY RESTRUCTURING THEIR GENOMES AS PART OF THE RESPONSE." (EMPHASIS MINE)
All of the DNA sequence changes discussed here are random with respect to fitness just as neo-Darwinism states. The DNA changes elicited by environmental stress are neutral, beneficial, and detrimental with respect to fitness.
This is contra to what you posted above.
No, it is not. What would run contra to what I am saying is if specific environmental stresses caused only specific mutations that only resulted in an increase in fitness. This is not what we see. What we see is an increase in transposon integration all over the genome, some of which are beneficial and are selected for.

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 Message 529 by shadow71, posted 01-19-2011 5:22 PM shadow71 has seen this message but not replied

Taq
Member
Posts: 10072
Joined: 03-06-2009
Member Rating: 5.2


Message 544 of 968 (601466)
01-20-2011 6:20 PM
Reply to: Message 534 by shadow71
01-20-2011 11:58 AM


Re: The past five decades of research in genetics and molecular biology have brouRe: yawn
On this board the possibility of a non-Darwinian theory is never considered.
Sure it is. The problem is that the evidence just isn't there, or it is overplayed as in the case of both Shapiro and Koonin.
He, not me, mentions a possible intelligent cellular action in evolution.
Based on what evidence?

This message is a reply to:
 Message 534 by shadow71, posted 01-20-2011 11:58 AM shadow71 has replied

Replies to this message:
 Message 551 by shadow71, posted 01-20-2011 8:44 PM Taq has not replied
 Message 560 by shadow71, posted 01-22-2011 4:08 PM Taq has replied

Taq
Member
Posts: 10072
Joined: 03-06-2009
Member Rating: 5.2


Message 545 of 968 (601467)
01-20-2011 6:21 PM
Reply to: Message 536 by shadow71
01-20-2011 12:14 PM


Re: increased mutation rate is not directed mutation
I just don't see how Shapiro can be rejected out of hand.
You have things backwards. What evidence convinced you that Shapiro is right?

This message is a reply to:
 Message 536 by shadow71, posted 01-20-2011 12:14 PM shadow71 has replied

Replies to this message:
 Message 547 by RAZD, posted 01-20-2011 7:10 PM Taq has replied
 Message 550 by shadow71, posted 01-20-2011 8:42 PM Taq has replied

RAZD
Member (Idle past 1431 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 546 of 968 (601472)
01-20-2011 6:53 PM
Reply to: Message 537 by molbiogirl
01-20-2011 1:33 PM


Re: Shapiro's use of the word "intelligent"
Thank you molbiogirl, long time no see. Anything new in molecular self replication?
I suggest anyone who's interested in Shapiro's use of the word "intelligent" read this thread:
There is intelligence and intelligence ...
He is saying we need to think of cellular processes as interactive systems (as we do with neural nets) rather than one way, linear, cause-effect systems.
Curiously, that was exactly my impression. DNA has, over 3+ billion years, accumulated a lot of information* that it uses that during the non-random replication processes (the parts not affected by mutation, and therefore being most of the process/es). That can certainly be called an intelligent use of information, because it is non-random, but that does not make it an intentionally planned or mystically directed process.
Enjoy.

we are limited in our ability to understand
by our ability to understand
Rebel American Zen Deist
... to learn ... to think ... to live ... to laugh ...
to share.


Join the effort to solve medical problems, AIDS/HIV, Cancer and more with Team EvC! (click)

This message is a reply to:
 Message 537 by molbiogirl, posted 01-20-2011 1:33 PM molbiogirl has not replied

RAZD
Member (Idle past 1431 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 547 of 968 (601474)
01-20-2011 7:10 PM
Reply to: Message 545 by Taq
01-20-2011 6:21 PM


Re: increased mutation rate is not directed mutation
Hi Taq,
What evidence convinced you that Shapiro is right?
Or more to the point, that his (shadow71) interpretation of Shapiro is right.
Enjoy.

we are limited in our ability to understand
by our ability to understand
Rebel American Zen Deist
... to learn ... to think ... to live ... to laugh ...
to share.


Join the effort to solve medical problems, AIDS/HIV, Cancer and more with Team EvC! (click)

This message is a reply to:
 Message 545 by Taq, posted 01-20-2011 6:21 PM Taq has replied

Replies to this message:
 Message 554 by Taq, posted 01-20-2011 8:54 PM RAZD has seen this message but not replied

RAZD
Member (Idle past 1431 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


Message 548 of 968 (601477)
01-20-2011 7:37 PM
Reply to: Message 536 by shadow71
01-20-2011 12:14 PM


Re: increased mutation rate is not directed mutation
Hi shadow71,
Message 534: On this board the possibility of a non-Darwinian theory is never considered. Those who bring up the possibility are "uneducated". So I read James A. Shapiro and am posting his findings and conclusions.
btw, I used the term undereducated. In terms of levels of education I am undereducated compared to people like molbiogirl and Taq, and I learn from them. This does not mean uneducated (having zero knowledge on the subject).
Message 535: Please read my post 534 to Granny Magda.
Shapiro clearly states His belief in a potential of " possible intelligent cellular action in evolution."
Agreed, however he also clearly does not say that "changes are the result of planned, engineered functions" as you have. To go from one to the other requires a "leap-of-faith" rather than a logical conclusion ... or confirmation bias based of beliefs rather than information.
Would you agree that based on what I posted in Message 534 to Granny Magda, that I may not be suffering from confirmation bias?
Yes, because I still cannot get from "possible intelligent cellular action in evolution" to "changes are the result of planned, engineered functions.
Intelligence covers a broad spectrum. Computers are intelligent in their ability to store, process and use information, but idiots at creating novel concepts - the term idiot savant comes to mind. You may not think of a light switch as being intelligent, however a computer is little more than a vast number of switches programed to respond in certain ways to certain stimuli. The software in computers have accumulated ways to process information in repeatable ways, and this is what gives them the ability to arrive at "intelligent" solutions.
Like computers DNA has accumulated the results of billions of years of trial and error tests of billions and billions of various attempts at finding valid responses to ecological conditions and their changes. That does not mean that it can predict changes or intelligently morph in a certain direction as would be expected of "planned, engineered functions."
As Taq points out (mid=601461), the increased rate of mutation caused by "possible intelligent cellular action in evolution" is non-directional, with some beneficial, some neutral and some deleterious results. It is the increased rate of mutations that allows the beneficial mutations that do arise to be selected during crisis. If it were "planned, engineered functions" then there would be many beneficial and no deleterious mutations, and as this is not the case we can consider your concept of "planned, engineered functions" falsified.
Enjoy.

we are limited in our ability to understand
by our ability to understand
Rebel American Zen Deist
... to learn ... to think ... to live ... to laugh ...
to share.


Join the effort to solve medical problems, AIDS/HIV, Cancer and more with Team EvC! (click)

This message is a reply to:
 Message 536 by shadow71, posted 01-20-2011 12:14 PM shadow71 has replied

Replies to this message:
 Message 549 by shadow71, posted 01-20-2011 8:38 PM RAZD has replied

shadow71
Member (Idle past 2959 days)
Posts: 706
From: Joliet, il, USA
Joined: 08-31-2010


Message 549 of 968 (601482)
01-20-2011 8:38 PM
Reply to: Message 548 by RAZD
01-20-2011 7:37 PM


Re: increased mutation rate is not directed mutation
James A. Shapiro wrote;
4) Cellular Information Processing. While it is easy to see how advances in our understanding of genome organization and genetic change will impact theories of evolutionary processes, another development in contemporary biology is of less obvious but even more basic relevance. This is the growing realization that cells have molecular computing networks which process information about internal operations and about the external environment to make decisions controlling growth, movement, and differentiation. This realization has come, in large measure, from detailed genetic analysis of cellular processes and multicellular development. The inducible repair systems mentioned above provide a relatively simple, well-studied example. Bacterial and yeast cells have molecules that monitor the status of the genome and activate cellular responses when damaged DNA accumulates. The surveillance molecules do this by modifying transcription factors so that appropriate repair functions are synthesized. These inducible DNA damage response systems are sophisticated and include so-called "checkpoint" functions that act to arrest cell division until the repair process has been completed. When the checkpoints do not function, cell division proceeds before repair is completed, and the damaged cells die or produce inviable progeny. One can characterize this surveillance/inducible repair/checkpoint system as a molecular computation network demonstrating biologically useful properties of self-awareness and decision-making.
Razd writes
Agreed, however he also clearly does not say that "changes are the result of planned, engineered functions" as you have. To go from one to the other requires a "leap-of-faith" rather than a logical conclusion ... or confirmation bias based of beliefs rather than information.
When he says Molecular compuation network demonstrating biologically useful properties OF SELF-AWARENESS AND DECSION MAKING (emphasis mine) does that not speak of some sort of ability to make decisions based upon what the circumstances present?
How do you interpret the statement that "...that cells have molecular computing networks which process information about internal operations and about the external enviroment to make DECISIONS controlling growth, movent, and differentiation...
This clearly speaks of decision making processes .

This message is a reply to:
 Message 548 by RAZD, posted 01-20-2011 7:37 PM RAZD has replied

Replies to this message:
 Message 553 by Taq, posted 01-20-2011 8:51 PM shadow71 has replied
 Message 557 by Taq, posted 01-20-2011 8:58 PM shadow71 has seen this message but not replied
 Message 567 by RAZD, posted 01-22-2011 6:42 PM shadow71 has replied

shadow71
Member (Idle past 2959 days)
Posts: 706
From: Joliet, il, USA
Joined: 08-31-2010


Message 550 of 968 (601483)
01-20-2011 8:42 PM
Reply to: Message 545 by Taq
01-20-2011 6:21 PM


Re: increased mutation rate is not directed mutation
tag writes;
You have things backwards. What evidence convinced you that Shapiro is right?
His education, experience, studies, research and reputation in the field. He would truly qualify as an "EXPERT" in the legal field and would be able to testify at any trial on these issues.

This message is a reply to:
 Message 545 by Taq, posted 01-20-2011 6:21 PM Taq has replied

Replies to this message:
 Message 552 by Taq, posted 01-20-2011 8:47 PM shadow71 has replied

shadow71
Member (Idle past 2959 days)
Posts: 706
From: Joliet, il, USA
Joined: 08-31-2010


Message 551 of 968 (601484)
01-20-2011 8:44 PM
Reply to: Message 544 by Taq
01-20-2011 6:20 PM


Re: The past five decades of research in genetics and molecular biology have brouRe: yawn
tag writes;
Based on what evidence?
His 30 plus years of research in the field. Plus his eucation, etc.

This message is a reply to:
 Message 544 by Taq, posted 01-20-2011 6:20 PM Taq has not replied

Taq
Member
Posts: 10072
Joined: 03-06-2009
Member Rating: 5.2


Message 552 of 968 (601486)
01-20-2011 8:47 PM
Reply to: Message 550 by shadow71
01-20-2011 8:42 PM


Re: increased mutation rate is not directed mutation
His education, experience, studies, research and reputation in the field.
I didn't ask for his CV. I asked for the evidence that convinced you. What is it?
BTW, my username is Taq (with a Q). It's short for Thermus aquaticus which is the bacterial species famous for it's temperature tolerant DNA polymerase used in PCR (in case you were curious).
Edited by Taq, : No reason given.

This message is a reply to:
 Message 550 by shadow71, posted 01-20-2011 8:42 PM shadow71 has replied

Replies to this message:
 Message 561 by shadow71, posted 01-22-2011 4:17 PM Taq has not replied

Taq
Member
Posts: 10072
Joined: 03-06-2009
Member Rating: 5.2


Message 553 of 968 (601487)
01-20-2011 8:51 PM
Reply to: Message 549 by shadow71
01-20-2011 8:38 PM


Re: increased mutation rate is not directed mutation
When he says Molecular compuation network demonstrating biologically useful properties OF SELF-AWARENESS AND DECSION MAKING (emphasis mine) does that not speak of some sort of ability to make decisions based upon what the circumstances present?
Mutations are still observed to be random with respect to fitness which is the whole point. The cell does not sense antibiotics in the environment and then specifically mutate a specific gene to produce antibiotic resistance, as one example. Instead, random mutations produce the resistance which is then selected for.
Edited by Taq, : No reason given.

This message is a reply to:
 Message 549 by shadow71, posted 01-20-2011 8:38 PM shadow71 has replied

Replies to this message:
 Message 562 by shadow71, posted 01-22-2011 4:32 PM Taq has replied

Taq
Member
Posts: 10072
Joined: 03-06-2009
Member Rating: 5.2


Message 554 of 968 (601488)
01-20-2011 8:54 PM
Reply to: Message 547 by RAZD
01-20-2011 7:10 PM


Re: increased mutation rate is not directed mutation
Or more to the point, that his (shadow71) interpretation of Shapiro is right.
I think it may be more productive if we start with the data. Once we all agree on what the data says we can better discuss what Shapiro is really saying.

This message is a reply to:
 Message 547 by RAZD, posted 01-20-2011 7:10 PM RAZD has seen this message but not replied

shadow71
Member (Idle past 2959 days)
Posts: 706
From: Joliet, il, USA
Joined: 08-31-2010


Message 555 of 968 (601489)
01-20-2011 8:55 PM
Reply to: Message 542 by molbiogirl
01-20-2011 5:33 PM


Re: Shapiro's use of the word "intelligent"
miobiogirl writes inter alia;
Cognitive systems view of the genome, shadow. Not "intelligently designed genome".
Cognitive--cognition "The mental action or process of acquiring knowledge and undrstanding through thought , experience, and the senses."
Concise OXFORD AMERICAN Dictionary.
that sounds like intelligence as per Dr. Shapiro. He wrote that article for a lay audience and I don't think he was careless in the use of his words.
But we will probalbly agree to disagree on this.

This message is a reply to:
 Message 542 by molbiogirl, posted 01-20-2011 5:33 PM molbiogirl has replied

Replies to this message:
 Message 556 by jar, posted 01-20-2011 8:57 PM shadow71 has seen this message but not replied
 Message 559 by molbiogirl, posted 01-21-2011 12:35 PM shadow71 has replied

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