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Author Topic:   Question For Evo's Re: Fruit Fly Mutations
NosyNed
Member
Posts: 8996
From: Canada
Joined: 04-04-2003


Message 31 of 35 (187482)
02-22-2005 11:16 AM
Reply to: Message 30 by crashfrog
02-22-2005 11:05 AM


Expressed in the phenotype.
To get even more picky I'd say cancer was an expression in the phenotype.

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sfs
Member (Idle past 2533 days)
Posts: 464
From: Cambridge, MA USA
Joined: 08-27-2003


Message 32 of 35 (187486)
02-22-2005 11:24 AM
Reply to: Message 31 by NosyNed
02-22-2005 11:16 AM


Re: Expressed in the phenotype.
quote:
To get even more picky I'd say cancer was an expression in the phenotype.
Yes, but crashfrog specified mutations that can be passed on to one's offspring. Somatic mutations cause cancer, but they aren't passed on.

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 Message 31 by NosyNed, posted 02-22-2005 11:16 AM NosyNed has not replied

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Taqless
Member (Idle past 5913 days)
Posts: 285
From: AZ
Joined: 12-18-2003


Message 33 of 35 (187495)
02-22-2005 12:44 PM
Reply to: Message 29 by sfs
02-22-2005 10:27 AM


(And of course these aren't actually new genes, but changes anywhere in the genome, most of which does not consist [in the coding sequence] of genes.)
Just in case, I added the bold brackets.

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pink sasquatch
Member (Idle past 6023 days)
Posts: 1567
Joined: 06-10-2004


Message 34 of 35 (187499)
02-22-2005 12:56 PM
Reply to: Message 32 by sfs
02-22-2005 11:24 AM


Re: Expressed in the phenotype and inherited.
Somatic mutations cause cancer, but they aren't passed on.
Hereditary mutations also cause cancer, hence familial cancer syndromes.

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 Message 32 by sfs, posted 02-22-2005 11:24 AM sfs has replied

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sfs
Member (Idle past 2533 days)
Posts: 464
From: Cambridge, MA USA
Joined: 08-27-2003


Message 35 of 35 (187501)
02-22-2005 1:12 PM
Reply to: Message 34 by pink sasquatch
02-22-2005 12:56 PM


Re: Expressed in the phenotype and inherited.
quote:
Hereditary mutations also cause cancer, hence familial cancer syndromes.
Yes, I know, but they're not relevant to the present discussion. We're talking about Crashfrog's statement
quote:
Remember you're born with all the mutations you'll ever have - in terms of the ones you can pass on to your progeny.
I pedantically pointed out that some germ-line mutations occur after you're born. (This wasn't really relevant, since Crashfrog meant mutations that affect your phenotype, but at least it was correct.) Germ-line mutations that cause cancer, whether they're old mutations you inherit from your family or de novo mutations that occurred in forming you, are included in the set of mutations you're born with, so they've already been mentioned. Somatic mutations that cause cancer are not part of what we're talking about because you don't pass them on to your progeny.
None of this seems to have anything to do with much of anything, so I'm sorry I raised the issue.

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