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human and chimp/gorilla common ancestory
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Possible ERV role in gene regulation
Blaise, S., N. de Parseval, L. Benit, and T. Heidmann. 2003. Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution. Proc Natl Acad Sci U S A 100: 13013-13018.
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Mutational analysis
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Arguments pertaining to the randomness of viral insertion.
Lapuk AV, Khil PP, Lavrentieva IV, Lebedev YB, Sverdlov EDA human endogenous retrovirus-like (HERV) LTR formed more than 10 million years ago due to an insertion of HERV-H LTR into the 5' LTR of HERV-K is situated on human chromosomes 10, 19 and Y.
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