Protein folding, the origin of novelty and everything

TB,Given that synthetic chemistry can produce tommarow something that is not here today the problem as you have re-threaded it, seems to me to ask if out of the possible NUMBER of protein fold positions, is there really any biological reason to think we need consider them all. What if the ICR model remanded that we consider every location of an electron on the INTERIOR of the metal it is communicated on? From the concept of reproductive doubling we seem to be at a loss to virtually at least subtract off that which is not in truth real??