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Author Topic:   scientific end of evolution theory (2)
peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 37 of 214 (14531)
07-30-2002 9:48 PM
Reply to: Message 25 by mark24
07-29-2002 8:01 AM


dear mark,
You say:
"you can’t make any judgement on neutral/non-neutral rate until you can scientifically prove there is absolutely no function in the genes that you purport should display neutral rate mutation."
The redundant genes can be knocked out, so knocking them out does not say anything about the function of genes (or pseudogenes for that matter). Genes that can be knocked out are (at least) non-essential genes and that means -- according to NET -- that they suppose to change with faster rate than essential genes since there is no selective constraint on these genes (deduced from non-phenotype knock-outs). Is this so hard to comprehend? If it is, I recommend you to study the neutral theory. There are some excellent reviews written by Kimura himself. I invite you to do a search on the NCBI homepage.
and:
"No judgement allowed = no falsification."
That is why evolution can not be falsified, and therefor it is no science. As soon as one treats ET as science -- as I did in all my examples -- it falls. I don't understand why it doesn't make you a bit suspicious about the validity of the theory. When I found out I immediately recognized the theory as pretty feeble.
As I mentioned before everyone in free to believe whatever he/she wants, but don't tell me NDT (already forgotten about my falsification of random mutation?) is backed up by science, since it is NOT!!
Best wishes,
peter

This message is a reply to:
 Message 25 by mark24, posted 07-29-2002 8:01 AM mark24 has not replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 38 of 214 (14533)
07-30-2002 9:57 PM
Reply to: Message 31 by mark24
07-30-2002 5:02 AM


dear Mark,
You say:
"I’m well aware of neutral theory."
If so, what --according to you-- does it hold?
And:
"You have not shown evolution cannot work at the molecular level without being a hypocrite."
Strong words!
"Why? Because for your argument to be true, you need to demonstrate that the sequences you purport to be functionless, are. This is exactly the criteria you say evolutionists need to meet before they can derive phylogenies from transposons."
See my previous letter to you.
And:
"This is the third or fourth time I’ve posted this, why aren’t you addressing the main point?"
Because it is irrelevant to my falsifications of NDT.
In fact, you should be convinced now that NDT is not valid at the molecular level. I mean after I showed a falsification of random mutation and a falsification of natural selection.
Best Wishes,
Peter

This message is a reply to:
 Message 31 by mark24, posted 07-30-2002 5:02 AM mark24 has replied

Replies to this message:
 Message 40 by mark24, posted 07-31-2002 7:33 AM peter borger has not replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 39 of 214 (14537)
07-30-2002 10:43 PM
Reply to: Message 30 by Peter
07-30-2002 3:46 AM


dear Peter,
Your say:
"Why should these 'redundancies' (and you have yourself
stated that they are more likely to be 'of unknown function'
in any case) have a different mutation rate than any other
section of DNA ? (I've asked this before and you haven't given
an answer)"
Ever heard of neutral evolution theory? What does it say for DNA sequences that are not under selective constraint? Indeed, the suppose to change more rapidly!! In fact this has been well established. I recommend you to read reviews by Kimura on the topic, than you will find out. So either Kimura isn't right or NDT isn't, or both aren't.
And:
"If we didn't have sections of genetic make-up (with currently
unknown function and apparently no survival benefit to the
organism) we couldn't have natural selection at all, could we?
(This has been asked before and you have not answered)."
That is exactly the point! I try to show that natural selection does not work at the level of the genome and therefor the pardigm is wrong!!!!!! At last someone who gets the point.
And:
"You have in no way refuted random mutation."
Denial. One of evolutionists primary tactics. I clearly demonstrated with the Drosophila example that in this particular gene there is non-random (directed?) mutation, and if you had read the thread properly you would have seen that one of the first tenets of NDT is that non-random muations do NOT exist. You are free to ignore that, I don't mind. If you like I will also falsify common descent, and show that reconsiliation of gene and species trees is nothing but a mathematical trick to get the data in accord with the theory. (as a matter of fact, I already mailed the example of IL-1beta to you. Maybe we have to discuss that too).
And:
"Giraffes don't generate mutations to neck lenght control mechanisms becuase they need longer necks."
How do you know that?
And:
"Peppered moths (and they MUST rest somewhere during in the day
even if it is not near a biologist's trap ... most moths I have
seen during the day are sitting high on the wall of my house, or
on a high window) show a natural variation, and the distribution
of that variation can be affected by environmental conditions.
That IS natural selection isn't it?"
Yep, and it doesn't help NDT.
And:
"That we haven't found the exact molecular level explanation does
not refute the theory ... it just means there are pieces of the
puzzle missing ... we already know that."
That is a completely different issue. What I did is falsify the theory, and thus demonstrated the theory to be not good/wrong/incomplete.
As I mailed to John, there are not only a couple of pieces missing, but the ET cannot explain: 1) the origin of life, 2) the origin of genes, 3) (the origin of) biodiversity. I wouldn't call that just a couple of pieces. They are the quintessence.
And:
"Redundancy doesn't refute ToE, it is an expected feature."
We are starting to move in circles. I am not going to explain again that redundancies do not have a correlation with gene duplication etc... I already did that several times. Apparently, nobody gets the point.
You finally say that:
"Mutation enables evolution, and mutation happens."
I do not doubt that mutations happen. I am sure that they do not lead to evolution.
Also: Here you show your strong believe in mutations as the driving force of ET (I recommend you to read Spetner. At least his book is scientifically backed up).
"You have not shown that there are any non-random mutations in the sense that 'randommutation' is used in ToE, only that some sites are more prone to copy errors. This is good for ToE, it means that there is an observed mechanism that can explain away the 'you can't get enough mutations for that' arguments."
Wow, do you propose integration of this mechanism in the NDT?
That is pretty quick. So your conclusion will be: Peter Borger did not falsify anything?
I wish you well,
Peter

This message is a reply to:
 Message 30 by Peter, posted 07-30-2002 3:46 AM Peter has replied

Replies to this message:
 Message 41 by Peter, posted 07-31-2002 8:40 AM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 46 of 214 (14936)
08-07-2002 12:49 AM
Reply to: Message 43 by mark24
07-31-2002 10:54 AM


Dear Mark,
Could you please point out exactly where you think I use fallacies (mailnumber and quote) to support my view. It will make it a lot easier for me to respond,
Peter

This message is a reply to:
 Message 43 by mark24, posted 07-31-2002 10:54 AM mark24 has replied

Replies to this message:
 Message 49 by mark24, posted 08-07-2002 11:24 AM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 47 of 214 (14940)
08-07-2002 2:05 AM
Reply to: Message 41 by Peter
07-31-2002 8:40 AM


Dear Peter,
You write:
"My current opinion is that nothing that you have put forward
FALSIFY's ToE, that's true."
You are of very short memory.
Three weeks ago I mailed the topic: "molecular genetic evidence against random mutation" and thus I falsified the NDT. Although not admitted by Percy (maybe she should do that to create some clarity) it still stands as a falsification of the atheistic version of evolution theory (=NDT). I recommend you to read the thread again. Maybe that will open your eyes.
In the meantime I also provided a falsification (do you know what a falsification is, and why it is not so good for a theory?) of natural selection and thus demonstrated the NDT not to be valid on the level of the genome. What else do you want me to falsify?
Best wishes
Peter

This message is a reply to:
 Message 41 by Peter, posted 07-31-2002 8:40 AM Peter has replied

Replies to this message:
 Message 64 by Peter, posted 08-12-2002 6:43 AM peter borger has not replied
 Message 65 by mark24, posted 08-12-2002 7:25 AM peter borger has not replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 50 of 214 (14998)
08-07-2002 9:25 PM
Reply to: Message 48 by monkenstick
08-07-2002 5:02 AM


dear monkenstick,
You write:
"you haven't done anything of the sort borger, and if you think you have then you don't understand science very well"
Over the past few weeks I tried to discuss the concepts of non-random mutation and genetic redundancy and why they violate NDT. Apparently nobody understands these concepts and therefore I recommend you to read something about the topics to try to conceive the problem for ToE. It doesn't make sense to discuss the topics with people who don't understand the concepts.
And:
"you cannot falsify random mutation unless you can isolate mutation as one of the variables. When you look at the fly genome you cannot seperate the variables mutation and selection. You can only assume that selection has no affect (based on what little you actually know about the gene, which is in effect, nothing)"
Why don't you have a careful look at the figure presented in my first posting? You will notice that in all subpopulation of D. mel. the mutations are not introcuded at random. That falsifies NDT, whether you like it or not.
"so until you can isolate mutation from selection in an experimental setting, you cannot possibly "falsify" random mutation"
Well, actually I didn't, but D. mel's 1G5 gene did.
"pehaps the worst thing about it is that you seem to think that your interpretation of this article is the only correct one, despite the fact that it has been read by many other scientists and peer reviewed by experts who don't seem to think it falsifies NDT. Thats nothing but arrogance"
After disbelief the namecalling starts.
I wish you well,
peter

This message is a reply to:
 Message 48 by monkenstick, posted 08-07-2002 5:02 AM monkenstick has not replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 52 of 214 (15013)
08-08-2002 1:31 AM
Reply to: Message 51 by monkenstick
08-07-2002 11:30 PM


dear Monkenstick,
You say:
"The problem with this is that it doesn't even consider that these traits may be byproducts of genes which do serve functions which aid survival."
Actually these traits are not likely to be byproducts. A recent article demonstrates that the trait of musia is genetically determined and probably involves one gene (Science 2001, vol292, p1636-37 and ref's herein).
And:
"A person can use their hands to clap. Clearly being able to clap can have no survival advantages. So are hands redundant?"
Clapping for fun (which involves the musia gene) or clapping to scare of animals?
And:
"It isn't hard at all to imagine why the ability to regenerate has been turned off in some human tissues."
So actually we are talking (again) about the loss of a trait. I have already mentioned before (several times) that I am not that interested in the loss of traits, since it is not hard to conceive. I wonder how the original organism got the trait of regeneration.
And:
"Regeneration of FUNCTIONAl adult brain tissue is therefore extremely problematic, because the complex interactions of cells in development can't be "reset", because cells in an adult brain are terminally differentiated."
Maybe we simply do not know the mechanisms of de-differentiation, yet.
And:
"The reason lower organisms have the ability to regenerate is primarily most likely because they don't have the problem of regenerating the complexity which higher animals have to."
I notice a bit of a contradiction here. Since higher organisms are able to regenerate bones and liver it is not restricted to lower organisms. So, this is not an argument, let alone a reason.
You say:
"I don't know anything about botany, but remember that you are merely assuming that the trait is redundant, and that it doesn't offer any survival advantage. You can't really show that its redundant, until you can compare fitness of liana with and without this trait."
That experiment is not that hard to carry out. One only needs to compare the fitness of far-soared offspring and direct-neighborhood-of-the-parent-tree offspring. I predict that there will no difference in fitness.
And, finally:
"Loss of the gene doesn't show any obvious myopathy for the same reason that differences in muscle fibre composition are not treated as myopathies."
... and that makes it a redundant gene, isn't it?
Furthermore, you did not respond to my reply in the previous letter, where you say that:
"you haven't done anything of the sort borger (about the falsification of NDT), and if you think you have then you don't understand science very well"
Please read my posting on Drosophila's 1g5 gene. And, please explain to me how you think science works. (I always thought it was about theories and the validation of these theories through objective emperical research)
Have a good one,
Peter
[This message has been edited by peter borger, 08-08-2002]

This message is a reply to:
 Message 51 by monkenstick, posted 08-07-2002 11:30 PM monkenstick has not replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 54 of 214 (15042)
08-08-2002 8:02 PM
Reply to: Message 48 by monkenstick
08-07-2002 5:02 AM


dear Monkenstick,
You state:
"you cannot falsify random mutation unless you can isolate mutation as one of the variables. When you look at the fly genome you cannot seperate the variables mutation and selection. You can only assume that selection has no affect (based on what little you actually know about the gene, which is in effect, nothing)"
However, you are wrong. The mutations in D. melanogaster subtypes are introduced non-random in the 1G5 gene and do not affect the aminoacid sequence of the specified protein. Thus, the positions are neutral.
(I know it is hard to accept. The falsification of NDT, I mean)
best wishes
Peter

This message is a reply to:
 Message 48 by monkenstick, posted 08-07-2002 5:02 AM monkenstick has not replied

Replies to this message:
 Message 55 by mark24, posted 08-08-2002 8:04 PM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 56 of 214 (15048)
08-08-2002 8:58 PM
Reply to: Message 55 by mark24
08-08-2002 8:04 PM


dear mark,
Be patient. Your response needs a bit of my thoughts, but I will respond soon.
Peter

This message is a reply to:
 Message 55 by mark24, posted 08-08-2002 8:04 PM mark24 has not replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 58 of 214 (15069)
08-09-2002 3:09 AM
Reply to: Message 57 by monkenstick
08-09-2002 1:54 AM


Dear Monkenstick,
You say:
"like I said pete, you're assuming that they're neutral because they don't code for amino acids."
I say:
Apparently, you don't get it. The data not only demonstrates fixed introns, they also show mutations in the coding region inducing alternative codons that specify the same aminoacid (due to the degenerate [better is: redundant] genetic code).
Furthermore, since you don't agree on the paper I recommend you to sent a letter to Schmidt and Tautz (I will back you up, since I do not understand how such papers can be publishes in evolutionary literature). The authors demonstrate that the complete region changes according to neutral evolution. It's not may personal opinion. If you don't agree on neutral evolution maybe send a letter to Kimura too; to tell him that his neutral theory of evolution is wrong (what do you need a neutral theory of evolution for, anyway? Neutral evolution? What is it?).
I also recommend you to have a careful look at the figure, so you will notice that the mutations in distinct subspecies are introduced on the same spot and even the type of substitution is the same. This falsifies NDT, whether you like it or not. Why don't you read the complete thread?
And:
"There are many examples of conserved nucleotide sequences which do not code for amino acids, most of which are regulatory regions. Introns themselves neccessarily must have some selection pressure on their sequence in order for them to be recognised as introns, and not as exons."
Now you tell me something new!
And:
"If you are going to claim that all nucleotides which don't encode for amino acids are selectively neutral then you've got big problems when it comes time to explain homology in junk DNA and pseudogenes."
Firstly, there is NO junk DNA. This oldfashioned opinion is (going to be) demonstrated to be completely wrong, although it is still claimed by evolutionists as proof for evolution [have a look at the TALK-origin site, or read the "selfish gene" (Dawkins, who else. But what does he know about genes? He is a zoologist). It is a completely outdated view on DNA].
Secondly, I am not the one in big problems. That is the theory of evolution.
Best wishes,
Peter

This message is a reply to:
 Message 57 by monkenstick, posted 08-09-2002 1:54 AM monkenstick has not replied

Replies to this message:
 Message 59 by Andya Primanda, posted 08-09-2002 4:03 AM peter borger has not replied
 Message 61 by Mammuthus, posted 08-09-2002 9:52 AM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 66 of 214 (15317)
08-12-2002 9:17 PM
Reply to: Message 49 by mark24
08-07-2002 11:24 AM


dear mark,
You say:
"I never said you used fallacies to support your view, just that you allow yourself the luxury of not being able to show function/non-function of a sequence, yet absolutely require it for phylogenetic analysis that supports evolution."
Distortion. I said that since you don't know how viruses came into being you assume that they integrated in the DNA of an assumed ancestor and are now present in the same spot of the DNA in primates that descended from this ancestor. I've turned it up-side-down. I say that since we do not know the origin of (retro)viruses --but for sure they have there origin in the genome-- it may as well be assumed that the retroviruslike sequence fulfilled a role in speciation, genome stabilisation or other unknown function. A very close look at the DNA sequences within (sub)species would provide more clarity. (I said this before, but apperently you don't get that there are always more ways to interpret data. I also stated that the current data are discussed according to the paradigm of common descent through evolution, and --as you should know by now-- I objected to that).
You also say:
"In the very same thread you are assuming the total non-functionality of the GLO pseudogene."
Well, I am not the only one who is assuming that. It is generally acknowledged as a pseudogene.
And:
"Functionality doesn’t have to be known for phylogenetic inference, but it does have to be known if your argument depends on the lack of function of a particular sequence.
Since you have used the GLO vit c pseudogene as your evidence;
1/ Please cite the studies where human, chimp, orangutan, & macaque had their GLO genes knocked out, which you claim shows lack of function."
Here, I do not get your point. The GLO gene is a naturally knocked out gene in all species you cite above. According to the articlein PNAS it has been knocked out about 25 million years ago due to the introduction of a non-sense mutation in exon X (=ten).
2/ Assuming you can cite the studies of the knockouts above, how can you show the sequences never had a secondary function at some point, never, ever, EVER? Remember, you are claiming a falsification here, you need to be in possession of this knowledge.
Distortion. I said I COULD take the GLO gene as proof against random mutation (see also my comments to you in the other thread). I didn't do it because I have better examples.
And:
"If you cannot show that a nucleotide sequence never had function, then you cannot make a judgement on neutral rate mutation, as regards falsification of neutral theory, or the NDT for that matter."
I only quoted the authors.
Best wishes
Peter

This message is a reply to:
 Message 49 by mark24, posted 08-07-2002 11:24 AM mark24 has replied

Replies to this message:
 Message 68 by mark24, posted 08-13-2002 2:50 PM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 67 of 214 (15330)
08-13-2002 12:38 AM
Reply to: Message 61 by Mammuthus
08-09-2002 9:52 AM


dear Mammuthus,
You say:
"I lurk here from time to time because I find it facinating that anyone can be a creationist/IDer/Elvis Presley worshipper/my god can beat up your god etc. etc. in 2002 (not that it ever made any sense)."
The word "it" in you last sentence refers to the foregoing sentence? Please be more specific in your statements.
And:
"First, that is very arrogant of Mr. Borger to claim that Diethard Tautz and Karl Schmid do not know what they are talking about in their papers. (I will be glad to tell them next time I see them though they will both laugh and wonder why I am wasting the few minutes to type this here). Please explain why two people who studied biology (evolution in particular), generated the data, analyzed it, and yes, even published it are less qualified to draw their conclusions than Mr. Borger?"
First of all it is distortion of my words (which is a fallacy). If they studied the data they show, they would also have recognised non-random mutation in the 1G5 gene. (Since you seem to know the authors, please focus their attention to this peculiar phenomenon they did not discuss. Therefore I did it for them).
These authors discuss their data according to the current paradigms. These paradigms do not have to be correct. All I demonstrated is that if you have a careful look at the presented data we find a violation of random mutationand that falsifies NDT. Thus, the NDT is not complete, maybe even complete wrong. (as a matter of fact we are observing more and more genes that change in a directed manner:e.g. a very recent online article in JBC showed that the gene encoding the CD80 molecule --that is involved in costimulation of T cells-- is directed (JBC online august 2002; http://www.jbc.org/cgi/content/abstract/M205808200v1). This immediately falsifies NDT. Furthermore, it is known that subtilisin and interferon alpha also demonstrate directed mutations. Even viruses and bacteria are able to shuffle their genome in response to the environment and --whether you like it or not-- this falsifies NDT.
You also state:
"I could use Mr. Borger's logic to disprove creationsim."
I say:
Go ahead. Let's stick to the evidence, and watch out for fallacies.
You say:
"There is not one piece of physical evidence that supports the existence of Jesus."
fallacy #2: How does the foregoing sentence relate to your extensive conclusion? Apparently it is you who needs to brush up logics. Not only are these 'unwarranted conclusions', but they are also 'pars pro toto' fallacies. If this is your logics than I suddenly understand evolution much better.
Notably, your conclusion based on the above statement (thatis not even backed up by evidence, on the contrary) is:
"Therefore, the bible must be false, an intelligent designer does not exist and all ID based hypotheses are refuted. Ta da! Just disproved your side! So we can all get on with it and support the one true god...Homer Simpson..doh! This would be analagous to the I don't know what the pseudogene does so therefore it must do something and therefore it was designed and therefore evolution did not occur argument."
In addition, it should be noted that religion is per definition NO science, and if evolution IS science than I will treat it like that. I did this and I demonstrated the ToE to be falsifiable at all levels, in particular at the level of the genome. This is unacceptable for a scientific theory, at least, it SHOULD be unacceptable. So, what you --as an evolutionary biologist-- have to do is to get the theory in accordanc with the data, not the data in accordance with the theory! (If you don't know what I am referring to, please let me know, and we will discuss, for instance, the IL-1 beta genes)
You say:
"More seriously though, I work on "junk DNA" have a Ph.D. in human genetics and have been a working biologist for 12 years.
Congratulations!!
And:
"The last six on evolution..." (variation in DNA sequences, I presume?)"...and analyzing DNA from extinct animals such as mammoths. I can agree on Mr. Borger that Junk DNA is an awful term that was adopted prematurely..."
I say:
....and still propagated by evolutionists on internet, the papers, television etc. I strongly object to that!!
And:
"(the only thing we would agree on) ."
That remains to be seen. Do I notice 'jumping to conclusions' here?
And:
"However, there are functionless sequences that could be considered junk DNA but to many functionally uncharacterized sequences given this designation.
Mr. Borger says:
(Dawkins, who else. But what does he know about genes? He is a zoologist).
Ok Mr. Borger...what exactly are your credentials???
MSc (biochemistry, molecular biology), PhD (molecular medicine, gene expression and regulation)
"Since you don't accept the hypothesis/views/data of those who are not specialists in exactly the field under debate, show me what your credentials are regarding 1)evolutionary biology 2) "junk DNA"....if you do not hold a Ph.D. in a field directly related to these topics I guess we can say what does Mr. Borger know about genes? He is just a (profession unknown)."
I say:
What are you up to? Is this some kind of debating trick? Besides, my profession is mentioned on this site.
Furthermore you say:
"It seems from Mr. Borger's posts that he is intelligent..."
(thanks)
"...but has had no exposure to science or scientific method.
I say:
Based on what? Do I notice jumping to conclusions, again?
And:
"If he were truly interested in the topic he would take some classes in 1) scientific philosphy"
I did
"(2) biology"
I did a lot
"3) genetics (molecular or 'plain'?)"
I did both
"4)evolutionary biology"
I has my special interest although I do not come to the same conclusions as evolution biologists copy from the theory.
"and then with a few clicks at ncbi.nlm.nih.gov"
I say:
It is one of my favorite sites.
Furthermore, you state:
"...click on PubMed and actually find out about pseudogenes, hotspots, etc. rather than spout out that he is more able to evaluate a field than anyone who actually makes a living at it."
What makes you think I cannot analyse the data the authors present in literature? It is jumping to conclusions, again. (=fallacy #? I lost thread)
And you say:
"As a biologist I would assume that I am in no position to evaluate the current state of particle physics. That does not mean I cannot develope an informed opinion on the subject but it will not be worth much unless I really study and work on the subject."
I agree, but you could have a much better opinion if you took some particle physics classes. You would be independent of the opinion of others. I am independent of the opinions of other biologists, since I perfectly well understand the data they present in literature.
And:
"Mr. Borger and others seem to just say they have refuted a biological principle without even demonstrating that they are informed on the subject."
Based on...? You draw conclusion without any information. Are you an evolutionist?
Finally you say:
"Sorry to single you out Mr. Borger..."
(Thanks I'm flattered)
followed by:
"...but your post was inappropriate..."
Could you point out where exactly.
and:
"...in principle one could cut and paste the name of any of the anti-evolution posters on this board...except for Brad McFall who would require a Rosetta stone to understand in the first place.
(This is no argument)
Well, enough of that...at least before I bring down the wrath of Percipient...which would be ashame on my first post
Mark..if you are reading this, I really enjoyed your probability of rain post...very clever."
I say:
Of course you liked it since it was an inappropriate analogy. I recommend you to brush up on your logics.
And:
"Well, back to lurking...better yet..working"
Finally I would like to say to Mammuthus:
If you specialise in only one thing, you will never come to greater things than this one specialty. If one integrates several disciplines one will come to different insight that were beyond reach/imagination before.
I have the feeling that you work as follows:
Axioma 1: there is no creation,
Axioma 2: there is evolution.
And you are entitled to this, I don't mind.
But, who are you to tell other people that they are wrong in their axioma's. A PhD-ed molecular evolutionist? It doesn't impress me at all. Better try to integrate unbiased objective thinking in your 'Weltanschauung'.
I wish you well,
Peter

This message is a reply to:
 Message 61 by Mammuthus, posted 08-09-2002 9:52 AM Mammuthus has replied

Replies to this message:
 Message 70 by Mammuthus, posted 08-14-2002 7:44 AM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 69 of 214 (15409)
08-14-2002 2:36 AM
Reply to: Message 68 by mark24
08-13-2002 2:50 PM


dear Mark,
You state:
"Bullshit."
What do you mean? If you think this is an argument than you are wrong.
Let me explain once more. Some sequences --they do not have necessary to code for proteins-- may contribute to speciation, since they may fold the DNA in such way that certain genes are transcribes and others aren't. It is a huge mistake to think that the differences between species is the result of distinct genes. I know that the difference between species is mainly at the level of gene expression. It may well be that the observed shared retroviruses --as they are called since they resemble certain RNA viruses-- may have had a function in speciation, or maybe in stabilisation of the genome. Your interpretation of these sequences --I think-- is that they are junk DNA due to an inactive integrated virus in a common ancestor. But maybe your vision is entirely wrong. (I have the feeling that I keep repeating myself).
If we have a look in the DNA, some other primates also demonstrate shared retroviruses that are not present in human. So, maybe these sequences has a role in speciation in that lineage. I don't know, you don't know, nobody knows. Al you do is give it an interpretation according to common descent. And you even take them as evidence of common descent. But, what about genes that do not fit in the family tree? Are they evidence against common descent? As mentioned, I could take them as evidence against common descent and nobody would be able to proof that my vision is wrong. It all depends on the paradigm one holds. That is what I say.
(I recommend you to read this several times.)
You say:
"Actually, you’re right, I went off on a tangent.
Please allow me to redirect my argument."
I say:
Allowed.
In response to your comments on the GLO gene:
I do not have any objections to your statement that Chimps & humans are closely related & show only 4 substitutions between each other since divergence. This is what we see and I do not dispute this. What I dispute, however, is that you take it as evidence of common descent through evolution as a utterly naturalistic process. Only one of the nucleotides of the sequence of the GLO gene has to behave strangly in this inactivated gene --and it does, as pointed out in previous letter-- and it is no longer valid as proof. Why? Since we than cannot exclude directed mutation.
And you say about the authors Schmid and Tautz:
"They’re wrong then, aren’t they?"
I say:
Wrong with respect to what?
Best wishes,
Peter

This message is a reply to:
 Message 68 by mark24, posted 08-13-2002 2:50 PM mark24 has replied

Replies to this message:
 Message 73 by mark24, posted 08-14-2002 5:10 PM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 74 of 214 (15455)
08-14-2002 11:06 PM
Reply to: Message 70 by Mammuthus
08-14-2002 7:44 AM


dear Mammuthus,
Obviously, I said something that affected your temper, although that was not my intention. This happened before (several times) while discussing examples that seriously doubt the vision of NDT. As a matter of fact, I have the feeling (NB: feeling, not conclusion) that you did not read any of my threads and your reaction clearly demonstrates that you are not able to think beyond the current paradigm.
You say:
"If you could actually knock down any part of genetics or evolution by discovering something that nobody has seen that would be great. Upheavels in science are fantastic and bring about new discoveries...nay saying does not."
I recommend you to have a careful look at the data of Schmid and Tautz (see my posting). And I also invite you to point out where my reasoning goes wrong. As a matter of fact it is a falsification of NDT, and that is all I wanted to show on this site. However, since there was a lot of skepticism I was dragged into a discussion I was not really eager for. You will be dragged in the discussion too as you will find out.
Because, I take myself seriously, I defended my opinion where ever I could (as you will, either). I discovered the (undiscussed) data in S & T paper that falsified NDT and now, I cannot retreat by admitting that these data do not falsify NDT. Since they do.
Furthermore mammuthus says:
Peter says:
"The word "it" in you last sentence refers to the foregoing sentence? Please be more specific in your statements."
I say:
Unless you are being purposely obtuse you realize what the "it" refers to.
Actually, there could be different interpretations.
Peter says:
"This immediately falsifies NDT. Furthermore, it is known that subtilisin and interferon alpha also demonstrate directed mutations. Even viruses and bacteria are able to shuffle their genome in response to the environment and --whether you like it or not-- this falsifies NDT."
I say (mammuthus):
And I am the one with a logic problem? All this proves is that you do not understand the meaning of random mutation.
My response (pb)
O yes, I know what you are going to say. I do not know anything about evolution. Well, I heard this before as soon as I come up with examples that questions the valididty of random mutations and selection. (I'm sure I will hear these fallacies again as soon as I start my discussion on genes not present in apes but present in human and their alleged random origin. Of course, you are also invited to respond. The more scientific input the better. Certainly it will improve the discussion.)
And you (mammuthus) say:
Where is your proof in any of this that mutations are not random?
My say (pb):
Where is your proof that any of these mutations are random? Come on how can we discuss like this?
And you say (mam):
Where is the data that says you can predict in any given gamete where the next mutation occurs even for a "hot spot"? How does viral activation falsify NDT? You make bold statements but never elaborate as to exactly how this falisfies anything. Please be specific.
I say (pb)
I cannot yet be specific, since the underlying mechanisms are not yet clear. Time will reveal.
I said (mammathus):
"There is not one piece of physical evidence that supports the existence of Jesus."
Peter replies:
fallacy #2: How does the foregoing sentence relate to your extensive conclusion? Apparently it is you who needs to brush up logics. Not only are these 'unwarranted conclusions', but they are also 'pars pro toto' fallacies. If this is your logics than I suddenly understand evolution much better.
Notably, your conclusion based on the above statement (thatis not even backed up by evidence, on the contrary) is:
"Therefore, the bible must be false, an intelligent designer does not exist and all ID based hypotheses are refuted. Ta da! Just disproved your side! So we can all get on with it and support the one true god...Homer Simpson..doh! This would be analagous to the I don't know what the pseudogene does so therefore it must do something and therefore it was designed and therefore evolution did not occur argument."
In addition, it should be noted that religion is per definition NO science, and if evolution IS science than I will treat it like that."
I reply (mammuth):
1) Show me then one piece of evidence that Jesus lived (extra-biblical of course. You merely state that I am incorrect in saying there is no evidence that he lived.
My response (pb):
Ever heard of the 1st century jewish-roman historic Josephus Flavius? I recommend you to read his works.
2) It it gratifying that you listed intelligent design as not being a science but a religion.."it should be noted that religion is per definition NO science"
Peter says:
....and still propagated by evolutionists on internet, the papers, television etc. I strongly object to that!!"
I say (mammuth):
Please try and keep your emotions under control.
My response (pb):
Since when is objection an emotion?
Mammuth says:
The term junk DNA has been propagated primarily by the genomics community rather than specifically evolutionists...you really don't hold yourself to the standards of discourse you expect of others
I say (pb)
Junk DNA is an abused word that is eagerly spelled out by evolutionists. The layman who hears this on the TV/internet is completely overwhelmed by so much non-sense. It is misleading.
Similarly. The hoax around this socalled 7 million years missing link in the lineage of great apes. I've seen the skull (and with me the complete earth has seen it) on three different channels. All it is is a female gorilla. I didn't see it on TV that is was a female gorilla, I had to find out in the science section of a paper. I call this misleading of the public. Propaganda!
Peter says:
(Dawkins, who else. But what does he know about genes? He is a zoologist).
I replied (mammuth):
Ok Mr. Borger...what exactly are your credentials???
Peter replies:
MSc (biochemistry, molecular biology), PhD (molecular medicine, gene expression and regulation)
I said (mammuth):
"Since you don't accept the hypothesis/views/data of those who are not specialists in exactly the field under debate, show me what your credentials are regarding 1)evolutionary biology 2) "junk DNA"....if you do not hold a Ph.D. in a field directly related to these topics I guess we can say what does Mr. Borger know about genes? He is just a (profession unknown)."
Peter says:
What are you up to? Is this some kind of debating trick? Besides, my profession is mentioned on this site."
I say (mammuth):
Um...how is this a trick? YOU said that Richard Dawkins cannot be taken seriously ....
My comments:
This is distortion of my words (=fallacy). I said: "what does he know about genes". That is --in my opinion-- something different).
Mammuth continues:
...in discussing genetic evolution because he is a zoologist. 1) that assumes that he had no training in genetics as a zoologist which is very often an incorrect assumption (you jumping to conclusions)
I reply (pb):
So you infer that dawkins has a training in genetics? Could you substantiate that assumption?
2) you not having a background in evolution would exclude you from having an opinion by your own standard...no trick...your logic.
I say (pb):
Again distortion of my words. All I said that is: "Dawkins? What does he know about genes? He's a zoologist." Of course he is entitled to his opinions.
Peter says:
"What makes you think I cannot analyse the data the authors present in literature? It is jumping to conclusions, again. (=fallacy #? I lost thread)"
Re read what I said....you are not analyzing the raw data but you are JUMPING to the CONCLUSION that you are always right and they are wrong.
I say (pb):
You keep distorting my words. Where exactly do I say that I am always right? As a matter of fact I said in a reply to mark --about shared retroviruses-- that "I don't know, that he doesn't know and that nobody knows." That all I know: that I don't know!
You say (mammuth):
However, you never propose what the correct interpretation is I notice.
I say (pb):
Because we do not know the correct interpretation, the only thing we can do is have faith in paradigms. I said this before, but apparently you don't read what I write in other threads.
And you (mammuth) continue:
You merely say that they are incorrect but do not support or even give an alternative explanation...so yes, I do not think you are able to analyze the data the authors present in the literature as well as they do.
I say (pb):
As long as they can be falsified they are incorrect. What you fail to see is that I interpreted the data beyond the current paradigm.
Peter says regarding his study of evolution:
"I has my special interest although I do not come to the same conclusions as evolution biologists copy from the theory."
I say:
This statement makes no sense...another sweeping statement that everyone is wrong but you are right? Just a question of interest..have you ever read any of Darwin's works?
My reply (pb):
Let me be more specific. I did my evolutionclasses at Uni, and I passed. I read all about it for the last 10 years or so; from Darwin to Dawkins and from Behe to Spetner. (I prefer to read opposite opinions, it keeps me from being teneted). And I follow all articles on molecular evolution in Science and Nature.
Peter says:
"I agree, but you could have a much better opinion if you took some particle physics classes. You would be independent of the opinion of others. I am independent of the opinions of other biologists, since I perfectly well understand the data they present in literature."
1) You assume that I am dependent on the opinions of others
My response (pb):
On particle physics I presumed it. Yes.
2) You are completely dependent on the presentation of the data (rarely raw) of those biologists you claim to be independent of. We all are and that is why some of choose to do experiments on the subject ourselves...i.e. so as not to be dependent on the opinions of others.
My response (pb):
Data ara data. I am idenpendent of teir interpretation since I can interpret the data for myselfs. Often I encounter weard stuff, meaning: not in accord with the current paradigm.
3) You are certainly dependent on your opinion to the exclusion of all other considerations which is just as unfortunate as a blind follower.
Give me hard evidence that you can really
1) understand the theory of evolution
My response (PB):
That I am able to falsify the NDT should be sufficient.
2) propose an alternative
I say (pb):
Not here. But you will read about it.
3) show any support for that alternative
My response (pb):
I will.
4) really "with data" disprove that evolution can occur.
I say (pb):
I don't have to do that anymore, since Spetner already did this in a very scientific (mathematical) way. I will provide biological support for his vision.
You say (mammuth):
Peter says regarding Mark24's post (apologize but do not know which number it was)
"Of course you liked it since it was an inappropriate analogy. I recommend you to brush up on your logics."
I reply (mammuth):
I like Mark's analogy because it was funny and very appropriate.
My response (pb):
It was funny, although it was a faulty analogy.
You conclude (mammuth):
It is you who should brush up on your logics.
My response (pb):
No comments.
Peter says:
"Finally I would like to say to Mammuthus:
If you specialise in only one thing, you will never come to greater things than this one specialty. If one integrates several disciplines one will come to different insight that were beyond reach/imagination before.
I have the feeling that you work as follows:
Axioma 1: there is no creation,
Axioma 2: there is evolution.
And you are entitled to this, I don't mind.
But, who are you to tell other people that they are wrong in their axioma's. A PhD-ed molecular evolutionist? It doesn't impress me at all. Better try to integrate unbiased objective thinking in your 'Weltanschauung'."
I reply:
1) I do not specialize in one thing...again you make the assumption though you accuse me of making assumptions, jumping to conclusions, and uttering fallacies...rather amusing.
I say (pb):
Misinterpretation of my words. I said IF. You interpreted it as being meant personally. It wasn't, it was a general If-statement. Maybe I should have written: If ONE.... etc.
You say (mammuth):
correction:
Axioma 1) there is not a shred of evidence for creation
My response (pb):
I have the feeling that we have to define "evidence" first. But than we will get lost in setting up definitions. But why not? It's going to be along hot summer, anyway. And I have lots of --incubation-- time.
Axioma 2) there is a ton of evidence for evolution but an enormous amount of data missing as to how it works...not unlike the Law of Gravity. That is what makes it interesting.
All the socalled evidence have been obtained by verification of the old paradigm. Let's have a look whether the old paradigm can be falsified (on all levels). That would make it more interesting and more scientific. Let's redefine evolution theory.
Since we are in assumption mode in this part of the post..Peter Borger
Axioma 1) evolution cannot happen
If you mean that by application of the current knowledge on the laws of physics/biology evolution is impossible, I agree. (also read Spetner on the maths)
Axioma 2) My interpretations are always correct
Distortion. I offer another interpretation that is as correct as yours.
Peter says:
"But, who are you to tell other people that they are wrong in their axioma's. "
I reply:
Who exactly are you to tell people that they are wrong with their axioma's? Right back at you. I guess because I do not agree with you that I am not allowed to say you are wrong though you are free to do so?
Peter says:
"A PhD-ed molecular evolutionist"...get the facts straight...where did I claim to be a PhD-ed molecular evolutionist? And I really do not give a rats behind if my credentials impress you or not. I only put them out there as a bit of background information for others reading the posts.
I reply (pb):
Okay, I got carried away. And about the background, that's exactly what I do, but from a different stance.
Peter claims I need to:
"Better try to integrate unbiased objective thinking in your 'Weltanschauung'."
I reply:
Gleichfalls! You could use a heavy dose of this as well. Also support your ASSUMPTION that I do not use objective thinking. I will make an assumption given the tone of your responses to myself and others. Unbiased objective thinking means those who agree with you and nobody else...that is a poor way to engage in any endeavor much less a scientific one.
By all means attack the theory of evolution but
1) show that you understand the basics
2) propose the alternative
3) support it with hard data
You're repeating yourself. (I responded to these questions above).
If you could actually knock down any part of genetics or evolution by discovering something that nobody has seen that would be great.
My reply (pb):
Actually I focussed the attention at something that nobody had seen before and it instigated a big fuss (and you are part of it now, reluctantly I presume, but anyway). [See also my response above].
Upheavels in science are fantastic and bring about new discoveries...nay saying does not.
My reply (pb):
Maybe you could back me up as I try to get my discovery in a peer-reviewed journal? Co-authorship?
I like to conclude (pb):
Thanks for your responses and I hope for your future contribution.
"Final question to mammuthus, just to satisfy my scientific interest:
When can we expect the first cloned mammuth? That's what it's all about isn't it (not a conclusion, but my intuition).
Best wishes and have a nice day,
Peter

This message is a reply to:
 Message 70 by Mammuthus, posted 08-14-2002 7:44 AM Mammuthus has replied

Replies to this message:
 Message 77 by Andya Primanda, posted 08-15-2002 4:26 AM peter borger has replied
 Message 82 by Mammuthus, posted 08-16-2002 4:42 AM peter borger has replied
 Message 91 by derwood, posted 08-21-2002 12:03 PM peter borger has replied

peter borger
Member (Idle past 7686 days)
Posts: 965
From: australia
Joined: 07-05-2002


Message 75 of 214 (15464)
08-15-2002 3:34 AM
Reply to: Message 73 by mark24
08-14-2002 5:10 PM


dear mark,
I will have a careful look at your summary this weekend. Await my response.
Peter

This message is a reply to:
 Message 73 by mark24, posted 08-14-2002 5:10 PM mark24 has not replied

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