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Author Topic:   Genetic 'Bottlenecks' and the Flood
derwood
Member (Idle past 1876 days)
Posts: 1457
Joined: 12-27-2001


Message 12 of 59 (16246)
08-29-2002 12:42 PM


As far as mtEve goes, any emphases mine:
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Science 1995 Dec 22;270(5244):1930-6
The myth of Eve: molecular biology and human origins.
Ayala FJ.
University of California, Irvine, USA.
It has been proposed that modern humans descended from a single woman, the "mitochondrial Eve" who lived in Africa 100,000 to 200,000 years ago. The human immune system DRB1 genes are extremely polymorphic, with gene lineages that coalesce into an ancestor who lived around 60 million years ago, a time before the divergence of the apes from the Old World monkeys. The theory of gene coalescence suggests that, throughout the last 60 million years, human ancestral populations had an effective size of 100,000 individuals or greater. Molecular evolution data favor the African origin of modern humans, but the weight of the evidence is against a population bottleneck before their emergence. The mitochondrial Eve hypothesis emanates from a confusion between gene genealogies and individual genealogies.
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"The analysis presented in this study unambiguously shows that chimpanzees are our closest relatives to the exclusion of other primates. This is an important point that cannot be discounted. Further, the functional genetic differences that are represented by nonsynonymous sites also show this relationship. The notion that the great apes form a functional and evolutionary grade is not supported by our analysis. Rather, humans and chimpanzees are a functional evolutionary clade."
Page Not Found | University of Chicago

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