Register | Sign In


Understanding through Discussion


EvC Forum active members: 65 (9162 total)
2 online now:
Newest Member: popoi
Post Volume: Total: 915,806 Year: 3,063/9,624 Month: 908/1,588 Week: 91/223 Day: 2/17 Hour: 0/0


Thread  Details

Email This Thread
Newer Topic | Older Topic
  
Author Topic:   More non-mendelian genetics
Wounded King
Member
Posts: 4149
From: Cincinnati, Ohio, USA
Joined: 04-09-2003


Message 1 of 2 (193644)
03-23-2005 8:01 AM


A letter to Nature reports research suggesting that Arabidopsis can, in some instances, revert to a grandparental wild type allele instead of a parental mutant.
Nature AOP, published online 23 March 2005; doi:10.1038/nature03380
Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis
SUSAN J. LOLLE*, JENNIFER L. VICTOR, JESSICA M. YOUNG & ROBERT E. PRUITT*
A fundamental tenet of classical mendelian genetics is that allelic information is stably inherited from one generation to the next, resulting in predictable segregation patterns of differing alleles. Although several exceptions to this principle are known, all represent specialized cases that are mechanistically restricted to either a limited set of specific genes (for example mating type conversion in yeast) or specific types of alleles (for example alleles containing transposons or repeated sequences). Here we show that Arabidopsis plants homozygous for recessive mutant alleles of the organ fusion gene HOTHEAD5 (HTH) can inherit allele-specific DNA sequence information that was not present in the chromosomal genome of their parents but was present in previous generations. This previously undescribed process is shown to occur at all DNA sequence polymorphisms examined and therefore seems to be a general mechanism for extra-genomic inheritance of DNA sequence information. We postulate that these genetic restoration events are the result of a template-directed process that makes use of an ancestral RNA-sequence cache.
I haven't read through it all yet but it sounds pretty cool.
TTFN,
WK

Replies to this message:
 Message 2 by Adminnemooseus, posted 03-23-2005 7:16 PM Wounded King has not replied

Adminnemooseus
Administrator
Posts: 3974
Joined: 09-26-2002


Message 2 of 2 (193762)
03-23-2005 7:16 PM
Reply to: Message 1 by Wounded King
03-23-2005 8:01 AM


Are two versions of this PNT - Going to defer to the other one
Mendel wasn't entirely right is the other version.
This topic got proposed first, but the other version is better developed (although I'm not sure quoting the entire article is proper).
Topic rejected in a most gentle way,
Adminnemooseus

New Members should start HERE to get an understanding of what makes great posts.
Comments on moderation procedures (or wish to respond to admin messages)? - Go to:
General discussion of moderation procedures
Thread Reopen Requests
Considerations of topic promotions from the "Proposed New Topics" forum
Other useful links:
Forum Guidelines, Style Guides for EvC and Assistance w/ Forum Formatting

This message is a reply to:
 Message 1 by Wounded King, posted 03-23-2005 8:01 AM Wounded King has not replied

Newer Topic | Older Topic
Jump to:


Copyright 2001-2023 by EvC Forum, All Rights Reserved

™ Version 4.2
Innovative software from Qwixotic © 2024