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Author Topic:   The origin and evolution of protein superfamilies
Tranquility Base
Inactive Member


Message 2 of 5 (19351)
10-08-2002 10:03 PM
Reply to: Message 1 by mark24
10-08-2002 12:10 PM


^ This paper (from 1976 BTW) is one of the seminal papers identifying the superfamilies. Dayhoff is a famous seqeunce analysis guy who I cite in my lectures.
Superfamilies have conserved 3D structres and frequently little or no seqeunce similarity that is conserved across the family.
The statements made in this abstract are supersitions that presume evolution.
It does not discuss the acual origin of each family but the evolution within the families! Most papers on 'origin of families' are misleading entitled - they are talking about how the families spread out from a parent gene.
Gene families themselves are subsets of superfamiles or are at the superfamily level themselves. Families within superfamilies may or may not be convergent from an evolutionary POV.
[This message has been edited by Tranquility Base, 10-08-2002]

This message is a reply to:
 Message 1 by mark24, posted 10-08-2002 12:10 PM mark24 has replied

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 Message 3 by mark24, posted 10-09-2002 11:14 AM Tranquility Base has replied

  
Tranquility Base
Inactive Member


Message 4 of 5 (19447)
10-09-2002 9:08 PM
Reply to: Message 3 by mark24
10-09-2002 11:14 AM


^ Thanks for pointing it out. You found it amongst paleosol links?
I come across recent papers like this too but almost without exception the 'origin' they are talking about is the origin of diversification within the families.

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 Message 5 by derwood, posted 10-11-2002 2:04 PM Tranquility Base has not replied

  
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