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Author Topic:   Questions on "Random" Mutations
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 4 of 80 (409783)
07-11-2007 8:30 AM
Reply to: Message 1 by taylor_31
07-10-2007 6:09 PM


As I finished up a book about evolution today, I learned a surprising fact. Until today, I had assumed that mutations were totally random and there was no way to predict what would "show up" in any given mutation. I learned, however, that the processes by which mutations arise are actually nonrandom; rather, they are affected by many other factors. The only thing that's random is the effect that the mutation has on the organism's fitness.
I think you're confusing "random" with "uncaused".
The mutations are random in two closely related senses: first, as you say, with respect to the fitness of the organisms, and secondly, because we can't predict which mutations will occur.
By analogy, the fall of dice in a casino has underlying physical causes, but they do not favor any particular gambler, nor can we predict how they're going to come down.

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Replies to this message:
 Message 6 by taylor_31, posted 07-11-2007 8:05 PM Dr Adequate has replied

  
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 21 of 80 (410175)
07-13-2007 3:45 PM
Reply to: Message 6 by taylor_31
07-11-2007 8:05 PM


But I thought that the probability rates of different mutations happening are different. If that's true, then why can't you predict which mutation would occur?
If the probability rates of all the mutations were the same, then it would be statistically random.
Well, again, that's not what "random" means. The sum of two dice is random, but not all outcomes are equally likely; and this means that I can predict that 7 will come up a lot more than 12, on a statistical basis; but it still doesn't allow me to predict the outcome of a particular fall of dice.

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Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 35 of 80 (410291)
07-14-2007 6:54 AM
Reply to: Message 24 by MartinV
07-14-2007 1:59 AM


Re: Dawkins about random mutation
One of the most claimed and unproved darwinian statement is that behind evolution stands random mutation as the source of novelties.
Which is true by definition.
Breeders would be surprised by such a statement.
Nope.
We cannot breed lizards or tigers
Yes we can. Look at the systematic breeding of tigers with the albino mutation.
But this is obviously just a story:
St Bernards exist, and are the result of selecting desirable mutations, whether or not anyone ever tied a barrel to one.
But dogs are hardly the best example of artificial selection. Ladies and gentlemen, I give you Brassica oleracea.
Edited by Dr Adequate, : No reason given.
Edited by Dr Adequate, : No reason given.

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Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 36 of 80 (410292)
07-14-2007 7:02 AM
Reply to: Message 32 by MartinV
07-14-2007 6:03 AM


Re: Dawkins about random mutation
Dogs had massive genetic diversity before domestification.
Please demonstrate the "massive" genetic diversity of undomesticated Canis lupus as opposed to other species or stop making stuff up.
I was questioned also if there was any attempt to create new species by breeding throughout history.
Yes, it's been done several times.
Breeders know it very well
Why do you keep attributing your delusions to "breeders"?
So simple idea has to wait until midst 19 century to be discovered by Darwin.
Since you don't understand it, it can't be that simple.
On my opinion natural selection just removes extremities and is purely conservative force.
And all biologists have a different opinion, which is backed up by actual data rather than making stuff up.
Edited by Dr Adequate, : No reason given.

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Replies to this message:
 Message 38 by NosyNed, posted 07-14-2007 11:48 AM Dr Adequate has replied

  
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 37 of 80 (410293)
07-14-2007 7:07 AM
Reply to: Message 28 by MartinV
07-14-2007 3:21 AM


Re: Dawkins about random mutation
It took a lot of time till 19 century that idea of natural selection as one of the sourcees of speciation appeared. Breeders of many generations and civilisation somehow didn't notice the simple fact.
I'll tell you what else they hadn't noticed by Darwin's time:
"Ask, as I have asked, a celebrated raiser of Hereford cattle, whether his cattle might not have descended from long horns, and he will laugh you to scorn. I have never met a pigeon, or poultry, or duck, or rabbit fancier, who was not fully convinced that each main breed was descended from a distinct species. Van Mons, in his treatise on pears and apples, shows how utterly he disbelieves that the several sorts, for instance a Ribston-pippin or Codlin-apple, could ever have proceeded from the seeds of the same tree. Innumerable other examples could be given. The explanation, I think, is simple: from long-continued study they are strongly impressed with the differences between the several races; and though they well know that each race varies slightly, for they win their prizes by selecting such slight differences, yet they ignore all general arguments, and refuse to sum up in their minds slight differences accumulated during many successive generations." --- Darwin, Origin of Species, ch. 1.
Edited by Dr Adequate, : No reason given.

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Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 40 of 80 (410357)
07-14-2007 1:22 PM
Reply to: Message 38 by NosyNed
07-14-2007 11:48 AM


Conservative And Adaptive Selection
Conservative selection is where NS wipes out new mutations 'cos the old ones are better, as opposed to adaptive selection. So either MartinV is wrong about biology or he's wrong about biological terminology. Or both.

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Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 46 of 80 (410541)
07-15-2007 6:33 PM
Reply to: Message 41 by taylor_31
07-14-2007 10:49 PM


My problem, I think, is imagining and "seeing" the long progress ...
Could I first of all say that what follows is an answer to your post, but it'll take me a while to get round to the point. Sit down, take the weight off your feet, be patient. Let me tell you a story.
There's a chap called Tom Ray who designed a programming language called TIERRA. He used this language to write a program which copied itself.
A self-copying program undergoes reproduction which is one of the key elements of evolution. Another is mutation. Tom Ray built this in by specifying his programming language so that programs written in it would screw up occasionally, which simulates copying errors.
The third important element of evolution is selection. He didn't have to do anything in particular to simulate that, because a computer only has a finite memory, so programs trying to copy themselves are de facto in competition for a finite resource.
So he started off with one program which copied itself, with occasional copying errors and a selective pressure. The results exceeded his wildest dreams: the various "species" of programs which evolved from this one precursor showed behaviors analogous to predation, parasitism, and even sex. "Sex?", you ask. Yes: two programs co-operating to produce a third.
Now, here's the point. (I told you there was a point, didn't I?)
The point is that you can't imagine how this "digital sex" evolved. If you're thinking that maybe that's 'cos you don't know much about computer programs, let me tell you that I do, and that if anything that makes it even more baffling. I cannot imagine the specific pathways which led to the development of such a feature, within the confines of TIERRA. But I know for a fact that this happened.
Of course, in the case of TIERRA we could find out how it happened by looking in close detail at what happens when the simulation is working. But with evolution in the real world, the nearest we get to this is the fossil record, and by and large this only tells us about the development of bones.
Still, we can look at that. Consider, for example, the bones of the mammalian inner ear. This is about my favorite example of evolution, because it is the development of a complex (indeed, irreducibly complex) structure which we can see happening in the fossil record. We don't have to imagine the process, we can look at the bones.
When we can check up on evolution in this way, it's clear how it happened and it makes perfect sense. When we can't see all the stages, then I agree that they are difficult to imagine, but that says more about our powers of imagination than it does about evolution. As the example of TIERRA shows, our difficulty in imagining something doesn't make it impossible or even improbable.
I hope my comments on this thread have been helpful to you.

This message is a reply to:
 Message 41 by taylor_31, posted 07-14-2007 10:49 PM taylor_31 has replied

Replies to this message:
 Message 47 by MartinV, posted 07-16-2007 2:35 PM Dr Adequate has replied
 Message 63 by taylor_31, posted 07-18-2007 9:01 PM Dr Adequate has replied

  
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 53 of 80 (410752)
07-17-2007 4:22 AM
Reply to: Message 47 by MartinV
07-16-2007 2:35 PM


But most programs do not copy themselves nowadays.
However, I was not talking about "most programs", but about one which does copy itself.
Another example is evolution of programming languages. If another civilisation digged up in year 20.000 some big shop's computer network it wouldn't be correct making assumption that language Java running on servers evolved by RM/NS from some outdated host language like Fortran, Algol or PL/1. Even if both language have "If" and "End-if" clause it doesn't mean they have common ancestor or even creator. In fact both languages have independent origin.
Of course. In order to know whether a program is the result of a quasi-evolutionary process, or of design, we need to know whether it was in fact produced by design or by reproduction, variation, and selection.
So extrapolating experience with TIERRA (let say civilization in year 20.000 use only this language) to history of "evolution" of programs and programming languages would be misleading.
And so of course I have not done so, as you would know if you'd actually read my post instead of wittering on about the first thing that popped into your head when you noticed that I'd mentioned evolution and programming languages in the same post.
The English language is not a Rorschach inkblot, it actually conveys specific ideas.

This message is a reply to:
 Message 47 by MartinV, posted 07-16-2007 2:35 PM MartinV has replied

Replies to this message:
 Message 54 by MartinV, posted 07-17-2007 12:06 PM Dr Adequate has not replied

  
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 67 of 80 (411238)
07-19-2007 4:02 PM
Reply to: Message 58 by MartinV
07-17-2007 3:21 PM


Re: Really BAD analogy.
I don't see a point. Let say we have at the beginning 1.000 Englismen and 500 German. If individuals are not passed on the number of individuals would decrease each race. After some rounds we would have 50 sportsmen, Englismen and German separated to their own boats. We would have homozygous groups - all German or all English.
Oh, for pity's sake.
It's got nothing to to with heterozygosity. He's talking about how recombination and selection produces set of genes --- different genes, DIFFERENT GENES --- which are suited to one another.
Of course you don't see the point. You never see the point of anything. This is because, as you admitted, you don't bother to read the things you're pretending to reply to. As I said, it's not a Rorschach test. The point of what Dawkins wrote is not the subconscious ideas it stirs up in your head after you skim-read it and pick out a few words.
Could you just try to be right about something, just for once?

This message is a reply to:
 Message 58 by MartinV, posted 07-17-2007 3:21 PM MartinV has replied

Replies to this message:
 Message 69 by MartinV, posted 07-20-2007 11:50 AM Dr Adequate has replied

  
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 70 of 80 (411414)
07-20-2007 2:18 PM
Reply to: Message 69 by MartinV
07-20-2007 11:50 AM


Re: Really BAD analogy.
So, first you tell me that you don't read my posts, then you tell me that you are not interested in my opinions --- and then, in an attempt to refute me, you babble out a load of garbage that has nothing to do with my opinions or my posts.
This is consistent, certainly. Don't you worry that it is also frickin' stupid?
If you can't be bothered to find out what I think, you will never, ever, be able to find an error in my thinking. In particular, your latest babble has nothing whatsoever to do with anything that I said, or that Dawkins said, or that anyone has said. It's just your lonely raving about something you haven't bothered to read.

This message is a reply to:
 Message 69 by MartinV, posted 07-20-2007 11:50 AM MartinV has replied

Replies to this message:
 Message 72 by MartinV, posted 07-20-2007 4:05 PM Dr Adequate has replied

  
Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 71 of 80 (411423)
07-20-2007 2:52 PM
Reply to: Message 63 by taylor_31
07-18-2007 9:01 PM


Correct me if I'm wrong, but isn't this a simplified version of bona fide natural selection?
Yes, absolutely. But this observation doesn't change the point I was making, which is that we cannot imagine the precise processes which went on to produce sexually reproducing computer programs.
Can't we use genomes to compare species and then postulate how evolution has progressed?
Up to a point. However, looking at the differences between a chimp genome and a human genome don't reveal to us how (for example) true grammatical speech evolved, nor allow us to imagine how it happened.

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Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 73 of 80 (411435)
07-20-2007 4:31 PM
Reply to: Message 72 by MartinV
07-20-2007 4:05 PM


Re: Really BAD analogy.
You don't think. You just repeat Dawkins arguments like a parrot. Obviously you don't see difference between alleles and genes and that GENES are polymorphic. Because you don't realize that phenotyp of a sexualy reproduced organism is the result of genetic and epistatic interactions of genotype which is in each generation different you consider story about "GENES in boat" as wonderful. You consider any close insight and change of "GENE boat" for more realistic "Allele boat" only as "babbling".
This supposed critique of my posts would be so much more relevant if you'd bothered to read my posts, or if it had anything to do with my posts. But as you have admitted, you can't be bothered to read my posts before replying to them. This is why your babble has no relevance to my posts, or to anything else.
Edited by Dr Adequate, : No reason given.

This message is a reply to:
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Dr Adequate
Member (Idle past 303 days)
Posts: 16113
Joined: 07-20-2006


Message 74 of 80 (411443)
07-20-2007 4:52 PM
Reply to: Message 72 by MartinV
07-20-2007 4:05 PM


Re: Really BAD analogy.
I was going to explain to you further the difference between the real world and the magic delusional fantasy fairyland in your head, but then I noticed that I've already done so in post #70:
Dr Adequate writes:
So, first you tell me that you don't read my posts, then you tell me that you are not interested in my opinions --- and then, in an attempt to refute me, you babble out a load of garbage that has nothing to do with my opinions or my posts.
This is consistent, certainly. Don't you worry that it is also frickin' stupid?
If you can't be bothered to find out what I think, you will never, ever, be able to find an error in my thinking. In particular, your latest babble has nothing whatsoever to do with anything that I said, or that Dawkins said, or that anyone has said. It's just your lonely raving about something you haven't bothered to read.
Let me know when you are capable of understanding that, and then I shall continue your slow and painful introduction to reality.
Edited by Dr Adequate, : No reason given.

This message is a reply to:
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