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Author Topic:   Is Reproductive Success the Gold Standard?
Wounded King
Member
Posts: 4149
From: Cincinnati, Ohio, USA
Joined: 04-09-2003


Message 12 of 20 (497099)
02-01-2009 6:52 PM
Reply to: Message 7 by NosyNed
01-31-2009 5:32 PM


Re: DNA repair and selection
I'm not sure you can be correct that it uses the "other strand" because it comes into play when it is replicating a strand. But I don't know.
Lyx2no can be at least partially right, one mechanism of DNA repair during replication is 'mismatch' repair, which as the name implies is based upon finding mismatches between bases on complementary strands.
And of course the obligatory wiki link, for more information.
TTFN,
WK

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 Message 7 by NosyNed, posted 01-31-2009 5:32 PM NosyNed has not replied

Replies to this message:
 Message 13 by RAZD, posted 02-01-2009 9:08 PM Wounded King has replied

  
Wounded King
Member
Posts: 4149
From: Cincinnati, Ohio, USA
Joined: 04-09-2003


Message 15 of 20 (497171)
02-02-2009 8:54 AM
Reply to: Message 13 by RAZD
02-01-2009 9:08 PM


Re: DNA repair and selection
Hi Razd,
Bluejay has it right, I was talking about the 2 complementary strands making up 1 DNA double helix rather than 2 distinct copies of a gene. There is a mechanism which allows for what you describe, it is called gene conversion and it does involve mismatch repair. During recombination, which can occur when homologous stretches of DNA become aligned as in meiosis, mismatch repair mechanisms can cause non identical stretches to become identical leading to the effective copying of a stretch of genetic material from one chromosome to the other.
TTFN,
WK

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 Message 13 by RAZD, posted 02-01-2009 9:08 PM RAZD has seen this message but not replied

  
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