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In this paper the authors describe a series of crosses for 9 lines of Acantocyclops which had well characterised gentics and morphology and measured their comparative reproductive isolation on these bases (Grishanin et al., 2006). This set of species/subspecies showed multiple viable crosses betweeen partners with different chromosome numbers.
The common European shrew (Sorex araneus) has a highly variable number of chromosomes within a single species. There is some genetic isolation of karyotypic races, but also hybridization.
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