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Author Topic:   Adding information to the genome.
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 46 of 280 (532243)
10-22-2009 9:13 AM
Reply to: Message 40 by Dr Jack
10-22-2009 5:55 AM


Now, the -lactalbumin gene has substantial sequence similarity to a gene family that code for lysozymes (specifically to Ca2+ binding c-lysozymes).
The material I found suggested the similarity was in the order of 35-40%. Hardly "substantial" when you consider human and mouse DNA is 92% similar.
The calcium-binding lysozyme that's so strikingly similar to -lactalbumin isn't present in humans, is it? So it has to be a case of gene duplication followed by "whoops, we've lost one".
All in all, not a great example of growing the genome through gene duplication.
Edited by Kaichos Man, : No reason given.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 40 by Dr Jack, posted 10-22-2009 5:55 AM Dr Jack has replied

Replies to this message:
 Message 47 by Dr Jack, posted 10-22-2009 9:56 AM Kaichos Man has replied
 Message 48 by Dr Jack, posted 10-22-2009 10:02 AM Kaichos Man has replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


(1)
Message 53 of 280 (532383)
10-23-2009 5:50 AM
Reply to: Message 50 by Briterican
10-22-2009 5:53 PM


Re: deleted
Edited by Briterican, 23-Oct-2009 9:40 AM: Added nothing to the discussion. Please accept my self-censorship as an apology.
Oh, don't be so self-deprecating, Briterican. Adding nothing to the discussion never stopped Doctor Adequate...

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

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Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 54 of 280 (532389)
10-23-2009 5:58 AM
Reply to: Message 47 by Dr Jack
10-22-2009 9:56 AM


It's possible we've subsequently lost it, but that is hardly relevant to the point, is it?
It is when the point is adding information to the genome. Losing one gene and gaining another puts you back at even.
Incidentally, some of the research suggested the a-lactalbumin gene evolved from Ca++ lysozyme, but most of it suggested they both evolved from a 'common ancestor' gene. Can you cast any light on this?

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
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Replies to this message:
 Message 59 by Blue Jay, posted 10-23-2009 11:20 AM Kaichos Man has replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 55 of 280 (532390)
10-23-2009 6:03 AM
Reply to: Message 48 by Dr Jack
10-22-2009 10:02 AM


Re: An aside on similarity
Figures such as the 92% mouse DNA figure come from a completely different method which simply involves dropping DNA from both into solution and measuring temperature changes. These methods give completely different numbers.
You learn something new every day. While I don't doubt that what yousay is true, there are significant "ultraconserved" areas of identical sequence between humans and mice aren't there? (Not suggesting they are anything like the order of 92%, but it's interesting).

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 48 by Dr Jack, posted 10-22-2009 10:02 AM Dr Jack has not replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 56 of 280 (532392)
10-23-2009 6:19 AM
Reply to: Message 45 by Modulous
10-22-2009 8:59 AM


Re: laugh first think second?
Two hundred years after Darwin's birth, the theory of evolution by natural selection remains a cornerstone of biology, as it has withstood this and other challenges
You, and Mr Jack, and RADZ, fail to see the point of the humour. It's not that Darwin got it wrong. It's that this scientist decided to make an editorial point about the theory and used, as it turned out, a very poor example to do so.
I don't know if you're old enough to have been exposed to Monty Python, but it's in the same vein as:
"They said I was mad to build a castle in a swamp, but I built it anyway- just to show them!...it sank into the swamp...

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

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Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


(1)
Message 58 of 280 (532397)
10-23-2009 6:44 AM
Reply to: Message 51 by RAZD
10-22-2009 6:28 PM


Re: laugh first think second?
Lactation appears to be an ancient reproductive feature that pre-dates the origin of mammals.
"Appears to be". Uh-huh.
A cogent theory for the evolution of the mammary gland and lactation has been provided
Oh good. Cogent. We can relax.
The features of current mammals were gradually accrued through radiations of synapsid ancestors
What, no "Once upon a time, long, long ago"?
and the mammary gland is hypothesized to have evolved from apocrine-like glands associated with hair follicles
Oh dear, an hypothesis. Let's hope it's cogent.
Oftedal suggests that these glands evolved from providing primarily moisture and antimicrobials to parchment-shelled eggs
Oh dear. He's got the proto-mammal suckling an egg on her hair follicle. Cogency alert!
Fossil evidence indicates that some of the therapsids and the mammalia-formes, which were present during the Triassic period more than 200 million years ago, produced a nutrient-rich milk-like secretion.
Amazing! 200 million year old fossils, and not only can they tell that they secreted stuff, they even know what was in it!
later evidence and increased knowledge can result in revisions of such ideas
Hmm. You know, I'm starting to like Darwin's version more and more...
Enjoy.
I did. Immensely.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 51 by RAZD, posted 10-22-2009 6:28 PM RAZD has replied

Replies to this message:
 Message 60 by Blzebub, posted 10-23-2009 12:37 PM Kaichos Man has not replied
 Message 62 by Dr Jack, posted 10-23-2009 2:19 PM Kaichos Man has replied
 Message 63 by RAZD, posted 10-23-2009 8:23 PM Kaichos Man has replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 64 of 280 (532639)
10-25-2009 8:06 AM
Reply to: Message 59 by Blue Jay
10-23-2009 11:20 AM


Re: Addition of Information
So, you agree that information can be added, as long as other information is taken away simultaneously?
No. I'm saying that if information is added, and other information is taken away simultaneously, then there's no nett increase in information.
And, you also realize that this requires every mutation that increases information to be accompanied by a simultaneous mutation that decreases information to the same or greater extent, right?
No. See above.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 59 by Blue Jay, posted 10-23-2009 11:20 AM Blue Jay has replied

Replies to this message:
 Message 70 by Blue Jay, posted 10-25-2009 7:32 PM Kaichos Man has not replied
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Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 65 of 280 (532640)
10-25-2009 8:08 AM
Reply to: Message 62 by Dr Jack
10-23-2009 2:19 PM


Re: laugh first think second?
The style you're bizarrely mocking is standard scientific style
No, it's standard evolution style. It would be an embarrassment to any other field of science.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 62 by Dr Jack, posted 10-23-2009 2:19 PM Dr Jack has replied

Replies to this message:
 Message 68 by Dr Jack, posted 10-25-2009 2:38 PM Kaichos Man has not replied
 Message 69 by Larni, posted 10-25-2009 3:42 PM Kaichos Man has not replied
 Message 76 by Dr Adequate, posted 10-26-2009 1:25 AM Kaichos Man has not replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 66 of 280 (532645)
10-25-2009 8:27 AM
Reply to: Message 63 by RAZD
10-23-2009 8:23 PM


Re: The last laugh is that evidence of lactation evolving shows added information
and amazingly these pores are inside the brood pouch for these animals. Who could have predicted that!
So Darwin was right? And the evolutionist scientist I quoted was wrong?
"disaccharide lactose (galactose 1—4 glucose) is contained in all milks, except for those of some marine mammals." This argues for common ancestry of all these organisms
And must therefore, logically, argue against common ancestry for those marine mammals.
Fossil records suggest that caseins were present during the Triassic, because the extensive bone and tooth development evident in the relevant species at stages before independent feeding would have required delivery of ample calcium.
What fossil records "suggest" is that caseins were present. That they were present in mammary secretion is pure conjecture, or to use your own words:
an untested explanation of the facts at this time
But don't worry. It'll soon turn up in a biology textbook near you as "fact".
Curiously, reality in general, and lactation in particular, are completely unaffected by your opinion, or your likes and dislikes.
Yeah. Ain't it the truth.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 63 by RAZD, posted 10-23-2009 8:23 PM RAZD has replied

Replies to this message:
 Message 67 by RAZD, posted 10-25-2009 12:55 PM Kaichos Man has replied
 Message 75 by Dr Adequate, posted 10-26-2009 1:22 AM Kaichos Man has not replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 78 of 280 (532840)
10-26-2009 9:00 PM
Reply to: Message 67 by RAZD
10-25-2009 12:55 PM


Re: The last laugh is that evidence of lactation evolving shows added information
And amusingly, you keep eagerly demonstrating the truth that your opinion is worthless in discussing reality.
RADZ, let's discuss reality.
The reality is that some scientists examined some fossils purported to be 200 million years old. From their examination, they deduced the following:
1. The creatures were too young to feed themselves.
2. The bone and tooth structures suggested an abundance of calcium.
3. The abundance of calcium suggested the presence of caseins.
4. The presence of caseins suggested mammary secretion.
This is the reality. Now let's ask a few questions.
In deciding whether a creature is old enough to feed itself, size is not an issue. The smallest herbivor can graze, the smallest carnivore can hunt small prey. The main consideration (particularly in a fossil) must be the development of teeth and bones. Given that these creatures had well-developed teeth and bones, why did the scientists decide they were too young to feed themselves?
Well developed teeth and bones certainly suggest an abundant supply of calcium, but why does it need to be in the form of caseins? A lot of eggs are primarily composed of calcium, after all. If calcium can be used to build the egg, why not the teeth and bones of the creature inside? Baby crocodiles don't recieve caseins from mammary secretion. Do they exhibit underdeveloped teeth and bones?
Now you may ask why trained scientists would draw the far-fetched conclusion of "mammary secretion" based on such dubious evidence. But to do so is to fail to understand the evolutionary paradigm.
The theory must be supported and explained. Lactation exists, therefore it must have evolved. It is the duty of every scientist to explain how evolution took place.
That's why in evolution, unlike any other field of science, alternative hypotheses are discarded solely on the basis that they don't support the theory. The theory validates the facts, not vice versa. If the facts are at variance to the theory, then they can't be facts. There is no better example of this than the 110 years during which the ToE was soundly falsified by the fossil record, until Gould and Eldredge came up with the theory of Punctuated Equilibrium.
Whether you agree with punctuated equilibrium or not isn't the point. Why wasn't the theory dropped during those 110 years?
Because faith hangs on. And make no mistake about it, atheism is a faith.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 67 by RAZD, posted 10-25-2009 12:55 PM RAZD has replied

Replies to this message:
 Message 79 by Blue Jay, posted 10-26-2009 11:05 PM Kaichos Man has replied
 Message 80 by RAZD, posted 10-26-2009 11:25 PM Kaichos Man has replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 81 of 280 (533018)
10-28-2009 7:09 AM
Reply to: Message 79 by Blue Jay
10-26-2009 11:05 PM


Re: The last laugh is that evidence of lactation evolving shows added information
I'm getting really sick of hearing this crap from you.
Dear me. Perhaps you should hear it from someone else:
"The concept of organic evolution is very highly prized by biologists, for many of whom it is an object of genuinely religious devotion, because they regard it as a supreme integrative principle. This is probably the reason why severe methodological criticism employed in other departments of biology has not yet been brought to bear on evolutionary speculation."
Conklin, Edwin G. (Professor of Biology , Princeton University)

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 79 by Blue Jay, posted 10-26-2009 11:05 PM Blue Jay has replied

Replies to this message:
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Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 85 of 280 (533118)
10-28-2009 10:17 PM
Reply to: Message 80 by RAZD
10-26-2009 11:25 PM


Re: The last laugh is that evidence of lactation evolving shows added information
Let's not try to pretend that atheists are your only adversaries in this debate.
Agreed, and I apologise. Suffice it to say that while not all evolutionists are atheists, it's a safe bet that all atheists are evolutionists.
The main consideration is the level of development of teeth and bones in comparison to earlier fossils and to fossils of other closely related (similar homologies) organisms living at the same time, it isn't just some arbitrary decision.
We know little about cynodontia's diet (that isn't conjecture, no matter how reasonable) and even less about their eating capacity and metabolism. All we know is that the juveniles were well supplied with calcium. Comparison with earlier "relatives" or contemporary homologs is not valid, as we see wide variety in diets/eating capacities/metabolisms in closely related species today.
This is poor logic at best
Why? It's very simple logic. If the presence of disaccharide lactose argues for common ancestory, then its absence must, ipso facto, argue against it. Therefore if the author wanted to argue for common ancestory, he chose a pretty weak premise on which to do so.
Cognitive dissonance is an uncomfortable feeling caused by holding two contradictory ideas simultaneously.
The 110 years during which evolutionists retained the ToE while knowing that the fossil record comprehensively contradicted the theory is probably history's best example of cognitive dissonance.
Amusingly another one of the early ways to deal with cognitive dissonance is to try to change the subject away from the issue where dissonance is getting bothersome.
If you are trying to change the subject, you don't write:
Whether you agree with punctuated equilibrium or not isn't the point.
What is this sentence if not an attempt to keep the discussion on topic?
Look, I obviously haven't made my point clear. I understand that evolution is dealing with events that happened a long time ago, and for which scant physical evidence now exists. I understand that because of these limitations, in most instances inference is the best scientists can hope for, and for that reason they must phrase their hypotheses in appropriatly careful language.
What I object to is the fact that many scientists are treating the difficulties incumbent in studying the deep past as a license to make any claim they like, and present it as "evidence".
For example, your authors use phrases like: "records suggest that...", and "is likely to be similar to..."
and yet you are perfectly comfortable in asserting:
Lactation demonstrates a new feature in members of the Cynodontia Clade that evolved through the adaptation of an existing feature to a new use.
Not a suggestion. Not a likelihood. A fact.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 80 by RAZD, posted 10-26-2009 11:25 PM RAZD has replied

Replies to this message:
 Message 87 by RAZD, posted 10-28-2009 11:16 PM Kaichos Man has replied

  
Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 86 of 280 (533119)
10-28-2009 10:57 PM
Reply to: Message 84 by Blue Jay
10-28-2009 9:07 PM


Re: Lesson learned: do not put extraneous content in posts to Kaichos Man
Any chance you'll comment on my argument that all sciences treat their well-established theories as the baseline from which they create new theories?
No other field of science is based on a fundamental theory that is unrepeatable, unfalsifiable and therefore unscientific.
Or, any chance you'll comment on why additions of information to the genome that don't result in a net increase of information
An addition of information is an increase in information. A change in information isn't. That isn't to say it (a change)can't result in an adaptive advantage, but this thread is specifically about the increase in the size of the functional, non-redundant genome over billions of years.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

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Replies to this message:
 Message 88 by Coyote, posted 10-29-2009 12:12 AM Kaichos Man has replied
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Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 89 of 280 (533134)
10-29-2009 12:57 AM
Reply to: Message 87 by RAZD
10-28-2009 11:16 PM


Re: Lactose added to genome is added information
Suffice it to say that while not all evolutionists are atheists, it's a safe bet that all atheists are evolutionists.
Nope. False logic again.
And you can prove it by naming an atheist who doesn't believe in evolution?
Are you really trying to argue that marine mammals are not related to other mammals based on one milk protein?
Absolutely not. That would be just as absurd as arguing that marine mammals are related to other mammals based on one milk protein. Which is what the author was attempting.
If you disagree with this argument then you need to supply a different explanation for the facts.
Okay, let's try a completely different tack. Let's say that Cynodonts did lactate and supply their young with caseins.
What's to say Cynodonts weren't mammals? As far as I can tell from the research (correct me if I'm wrong) we can't even prove they laid eggs. They had a couple of extra bones in their jaw. Does that mean they weren't mammals? Are there rules a mammal has to abide by in order to be a mammal?
For example, can a mammal be egg-laying? Can a mammal be poisonous?
The Platypus is both.
If Cynodontia were mammals, all arguments about their evolution of lactation become moot.
Edited by Kaichos Man, : typo

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
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Kaichos Man
Member (Idle past 4509 days)
Posts: 250
From: Tasmania, Australia
Joined: 10-03-2009


Message 90 of 280 (533137)
10-29-2009 1:08 AM
Reply to: Message 88 by Coyote
10-29-2009 12:12 AM


Re: Creationist propaganda about science vs. evolutionary sciences
The new field of genetics could have caused a major revision
Motoo Kimura stated that his Neutral Theory showed the "great majority" of evolution at the molecular level was caused by genetic drift and not natural selection. You don't regard this as a major revision?
Perhaps creationists should not try to dabble in science, eh? Being against science and the scientific method because of their religious beliefs, they tend not to learn enough about it to make meaningful comments.
Which ones in particular? Isaac Newton? John Sanford? Simon Conway Morris?
(I still remember the creationist who, on another website, lectured us on "the second law of thermal documents.")
And so he should! I bet you've never even heard of it...
Edited by Kaichos Man, : No reason given.

"Often a cold shudder has run through me, and I have asked myself whether I may have not devoted myself to a fantasy." Charles Darwin

This message is a reply to:
 Message 88 by Coyote, posted 10-29-2009 12:12 AM Coyote has replied

Replies to this message:
 Message 91 by Coyote, posted 10-29-2009 1:33 AM Kaichos Man has replied
 Message 92 by cavediver, posted 10-29-2009 4:48 AM Kaichos Man has replied
 Message 95 by Percy, posted 10-29-2009 8:31 AM Kaichos Man has not replied

  
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