EvC Forum: Human Mutation Rate

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Topic: Human Mutation Rate

Blue Jay

Member (Idle past 2718 days)

Posts: 2843

From: You couldn't pronounce it with your mouthparts

Joined: 02-04-2008

Blue Jay Posts Only

Message 1 of 5 (550000)
03-11-2010 10:13 PM

Here is an article from ScienceDaily about a new study that uses the whole-genome sequences of a husband and wife, and their son and daughter to determine the number of mutations that occur between generations.

Their results suggest that about 30 mutations are passed from each parent to each child (so, any child will have 60 new genetic mutations).

Granted, it's only one couple and two children, but it does shed some light on the topic, and may prove useful here on EvC. There have been a lot of comments on various threads here recently, and I thought everybody would be interested in seeing this.

Edited by Bluejay, : No reason given.

-Bluejay (a.k.a. Mantis, Thylacosmilus)

Darwin loves you.

Replies to this message:
	Message 2 by Wounded King, posted 03-12-2010 4:53 AM		Blue Jay has replied

Wounded King

Member

Posts: 4149

From: Cincinnati, Ohio, USA

Joined: 04-09-2003

Wounded King Posts Only

Message 2 of 5 (550025)
03-12-2010 4:53 AM

Reply to: Message 1 by Blue Jay
03-11-2010 10:13 PM

Wow, that article has some issues.

Everybody has about 22,000 genes, which contain the genetic blueprint for human life. This blueprint, called DNA, comprises more than 3 billion "base pairs" that determine genetic makeup. In 1990, scientists worldwide began assembling the entire sequence of base pairs in all 22,000 human genes, a process called sequencing. When they completed the project in 2003, the scientists had put together the complete picture of the proper sequence of base pairs in the human genome.

When all 22,000 human genes had been sequenced that was the sequence of the human genome? No it wasnt!! There was a whole shedload of other genetic sequence needed to make a complete human genome.

Having said that the paper itself is pretty interesting, though it doesn't seem that their estimates are really much different from previous ones.

TTFN,

This message is a reply to:
	Message 1 by Blue Jay, posted 03-11-2010 10:13 PM		Blue Jay has replied

Replies to this message:
	Message 3 by Blue Jay, posted 03-12-2010 10:45 AM		Wounded King has replied

Blue Jay

Member (Idle past 2718 days)

Posts: 2843

From: You couldn't pronounce it with your mouthparts

Joined: 02-04-2008

Blue Jay Posts Only

Message 3 of 5 (550052)
03-12-2010 10:45 AM

Reply to: Message 2 by Wounded King
03-12-2010 4:53 AM

Hi, Wounded King.

Wounded King writes:

When all 22,000 human genes had been sequenced that was the sequence of the human genome? No it wasnt!! There was a whole shedload of other genetic sequence needed to make a complete human genome.

Are you directing your complaint towards the news article, or the research paper?

Did they not actually sequence the whole genome?

For everyone else, I didn't post the citation itself. This is the abstract (a premium membership is required to view Science Express articles, though).