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Author Topic:   Genetic Similarities
Coragyps
Member (Idle past 760 days)
Posts: 5553
From: Snyder, Texas, USA
Joined: 11-12-2002


Message 5 of 10 (66049)
11-12-2003 1:23 PM
Reply to: Message 1 by TheoMorphic
10-28-2003 2:12 PM


my second question is what are the respective genetic differences between very dissimilar dogs (lets say st. bernards and chihuahuas... but i'll take anything really) and chimps and humans?
I'm guessing that even St Bernards and chihuahuas are more similar in DNA sequence than humans and chimps, but I have no data to back that up. I have, however, seen a study (the paper is at home - link tonight) that shows a couple of mice - different species of the genus Mus - that are considerably more different over 12,000 genes than are chimps and people.

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 Message 1 by TheoMorphic, posted 10-28-2003 2:12 PM TheoMorphic has not replied

  
Coragyps
Member (Idle past 760 days)
Posts: 5553
From: Snyder, Texas, USA
Joined: 11-12-2002


Message 6 of 10 (66150)
11-12-2003 10:18 PM
Reply to: Message 4 by TheoMorphic
11-12-2003 1:13 PM


i'm looking more for a specific example. is there an essential sequence of genetic material that all (or most) life has in common (maybe not exactly the same, but significantly similar)?
A biochem book that I have borrowed (I never had a biochem course!) shows that histone H4 changes 30 times more slowly after species branching events than does cytochrome C, and 100 times more slowly than hemoglobin. So plant and animal histone is very nearly identical - 3%, maybe, difference in amino acids. Cytochrome C is more like 45% different. Is this more like what you're after?
Re my post above: Enard, et al., Science, 296, pp 340-343, (2002). It's online with free registration at Science | AAAS
Their data, along with some they quote, has humans 1.08% divergent in some measure of our DNA from chimps, and 2.98% from orangutans. The common house mouse, Mus musculus, is 2.5% different from M. spretus and 4.5 from M. caroli.
The article is actually about how gene expression is very different in human vs. other ape brains, which may be why we (claim to be/are) smarter than them. It's worth a read.

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