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Author Topic:   The Bladderwort Test
AZPaul3
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Posts: 8562
From: Phoenix
Joined: 11-06-2006
Member Rating: 4.8


(2)
Message 6 of 25 (699239)
05-16-2013 8:30 AM
Reply to: Message 4 by caffeine
05-16-2013 4:40 AM


Given the new stem cell announcement yesterday we do have a way to resolve this issue.
Clone a chimp that has had its genome stripped of, let's say, half the identified junk DNA and see what kind of "thing" develops.
Better yet we could do this with a human genome. A republican one would help keep the horror to a minimum since it could be argued that republicans show no signs of being sentient beings.
Mengele would be so proud of me.
Edited by AZPaul3, : cuz

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Replies to this message:
 Message 7 by Dr Adequate, posted 05-16-2013 9:52 AM AZPaul3 has replied
 Message 10 by Taq, posted 05-16-2013 10:54 AM AZPaul3 has replied
 Message 15 by sfs, posted 05-16-2013 10:11 PM AZPaul3 has seen this message but not replied

  
AZPaul3
Member
Posts: 8562
From: Phoenix
Joined: 11-06-2006
Member Rating: 4.8


Message 11 of 25 (699250)
05-16-2013 11:35 AM
Reply to: Message 7 by Dr Adequate
05-16-2013 9:52 AM


As I recall, this has been done with mice. They were fine.
Mus musculus zombisus (frankenmouse)
But seriously, excising 0.1% is not much of a test when the present view is that more than half the genome is non-coding.
And a serious question: How do geneticists determine between coding and non-coding areas of the genome? Base pair repeats for 1000s of pairs? What else?

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 Message 13 by Taq, posted 05-16-2013 11:54 AM AZPaul3 has replied

  
AZPaul3
Member
Posts: 8562
From: Phoenix
Joined: 11-06-2006
Member Rating: 4.8


(1)
Message 12 of 25 (699251)
05-16-2013 11:40 AM
Reply to: Message 10 by Taq
05-16-2013 10:54 AM


Clone a chimp that has had its genome stripped of, let's say, half the identified junk DNA and see what kind of "thing" develops.
There are major bioethical problems with these types of experiments.
I let the humor get the better of me. That was not a serious suggestion.

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AZPaul3
Member
Posts: 8562
From: Phoenix
Joined: 11-06-2006
Member Rating: 4.8


(1)
Message 14 of 25 (699276)
05-16-2013 4:44 PM
Reply to: Message 13 by Taq
05-16-2013 11:54 AM


I would assume that gene detections is based on an upstream ribosome binding site, a recognizable promoter region, and intact reading frames. Eukaryotic genes will also have exon excision sites
Your are quite correct.
I keep forgetting that you do not have to look at the gene itself through mixing it in a bunch of chemicals to see what falls out the bottom anymore. These things are transcripted in data files in raw ATCG format. Computer programs then are used to search the files for specific sequences (known sequences from other genomes) or using AIs to identify likely novel sequences.
It gets quite complex.
Gene finding Strategies
And then this popped up:
quote:
Even the concept of a 'gene' is under revision. Genes have long been regarded as discrete entities located linearly along chromosomes, but recent investigations have demonstrated extensive transcriptional overlap between different genes. Specifically, genomic regions from otherwise distinct and apparently well characterized protein-coding loci (which may be very far apart in linear genomic space) often appear to combine to produce transcripts with the potential for encoding novel protein species.
source
Now even a gene may not be just its own gene but part of several different genes using this specific sequence.
Cool.
Edited by AZPaul3, : cuz

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AZPaul3
Member
Posts: 8562
From: Phoenix
Joined: 11-06-2006
Member Rating: 4.8


Message 19 of 25 (699392)
05-18-2013 12:50 PM
Reply to: Message 18 by Dr Adequate
05-18-2013 10:29 AM


Re: Virus infections?
Am I missing something?
Yes. You're missing the possibility that Taq may have momentarilly slipped a cog and relayed a picture to us that was not same one in his mind.

This message is a reply to:
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