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Author Topic:   Alzheimers cure?
RAZD
Member (Idle past 1405 days)
Posts: 20714
From: the other end of the sidewalk
Joined: 03-14-2004


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Message 1 of 3 (755002)
04-03-2015 9:39 AM


Possibly
quote:
New Alzheimer’s treatment fully restores memory function
Of the mice that received the treatment, 75 percent got their memory functions back.
Australian researchers have come up with a non-invasive ultrasound technology that clears the brain of neurotoxic amyloid plaques - structures that are responsible for memory loss and a decline in cognitive function in Alzheimer’s patients.
If a person has Alzheimer’s disease, it’s usually the result of a build-up of two types of lesions - amyloid plaques, and neurofibrillary tangles. Amyloid plaques sit between the neurons and end up as dense clusters of beta-amyloid molecules, a sticky type of protein that clumps together and forms plaques.
Neurofibrillary tangles are found inside the neurons of the brain, and they’re caused by defective tau proteins that clump up into a thick, insoluble mass. This causes tiny filaments called microtubules to get all twisted, which disrupts the transportation of essential materials such as nutrients and organelles along them, just like when you twist up the vacuum cleaner tube.
Publishing in Science Translational Medicine, the team describes the technique as using a particular type of ultrasound called a focused therapeutic ultrasound, which non-invasively beams sound waves into the brain tissue. By oscillating super-fast, these sound waves are able to gently open up the blood-brain barrier, which is a layer that protects the brain against bacteria, and stimulate the brain’s microglial cells to activate. Microglila cells are basically waste-removal cells, so they’re able to clear out the toxic beta-amyloid clumps that are responsible for the worst symptoms of Alzheimer’s.
The team reports fully restoring the memory function of 75 percent of the mice they tested it on, with zero damage to the surrounding brain tissue. ...
Could be good news. May also open up a new technique for getting medicines past the blood-brain barrier.
Interesting to see how this research hold up in further testing.
Enjoy
Edited by RAZD, : quote

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Replies to this message:
 Message 2 by AdminNosy, posted 04-03-2015 10:09 AM RAZD has seen this message but not replied

AdminNosy
Administrator
Posts: 4754
From: Vancouver, BC, Canada
Joined: 11-11-2003


Message 2 of 3 (755005)
04-03-2015 10:09 AM
Reply to: Message 1 by RAZD
04-03-2015 9:39 AM


From one old man....
This is very good to hear. But I have an understanding that the plaques are not always associated with Alzheimer's.

This message is a reply to:
 Message 1 by RAZD, posted 04-03-2015 9:39 AM RAZD has seen this message but not replied

AdminNosy
Administrator
Posts: 4754
From: Vancouver, BC, Canada
Joined: 11-11-2003


Message 3 of 3 (755029)
04-03-2015 2:44 PM


Thread Copied to Coffee House Forum
Thread copied to the Alzheimers cure? thread in the Coffee House forum, this copy of the thread has been closed.

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