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Author Topic:   Iconic Peppered Moth - gene mutation found
Taq
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Joined: 03-06-2009
Member Rating: 5.3


Message 17 of 76 (785372)
06-03-2016 4:55 PM
Reply to: Message 2 by Faith
06-02-2016 4:48 AM


Faith writes:
how is it that a mutation so suited to the needs of the creature just happened to come along at the right time? Aren't mutations random accidents in DNA replication, and very rare and so on? Or is the ToE now reverting to Lamarckianism?
Where is there any evidence that the mutation only came about when it was needed?

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Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


Message 18 of 76 (785373)
06-03-2016 4:57 PM
Reply to: Message 11 by Faith
06-02-2016 11:29 PM


Re: not wierd at all.
Faith writes:
Even a dominant can more or less disappear in a large population where the recessive is strongly selected. That's how you can get a predominantly blue-eyed population.
The only way you get dominant and recessive alleles of the same gene is through mutations. The reason that they are dominant and recessive is due to DNA sequence differences brought on by mutations.
Edited by Taq, : No reason given.

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Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


Message 57 of 76 (785544)
06-06-2016 5:52 PM
Reply to: Message 19 by Faith
06-03-2016 7:43 PM


Re: not wierd at all.
Faith writes:
That's pure theory, not something known by observation.
It is known by observation as is being discussed in this thread. Another example is brown and black colored pocket mice:
Just a moment...
We have those exact observations.
If genetic material was built in from the Creation it included all the dominant and recessive forms of alleles and their combinations just as Mendel spelled them out.
Of the sequence differences between these alleles, which are you saying could not be produced by the observable mechanisms of mutation?
Edited by Taq, : No reason given.

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Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


Message 58 of 76 (785545)
06-06-2016 5:53 PM
Reply to: Message 20 by Faith
06-03-2016 7:50 PM


Faith writes:
In Tangle's original post where he quoted the date for its appearance in the late 1800s at the height of the Industrial Revolution.
Where did you show that this was the ONLY time the mutation occurred?
Edited by Taq, : No reason given.

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Taq
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Posts: 10045
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Member Rating: 5.3


(1)
Message 59 of 76 (785546)
06-06-2016 6:00 PM
Reply to: Message 24 by jar
06-03-2016 10:12 PM


The thing Faith needs to remember is that it really is a multipart system. Mutations causing dark moths may well have been happening all along but before the soot phase of the industrial revolution they were simply dinner. It was only when the selection pressure changed that the dark moths had an advantage.
It was selection that determined this particular mutation got preserved. Any earlier examples of a similar mutation would have just been putting food on the table.
The same thing happened in pocket mice. They also evolved black coloration, and it was a dominant allele. However, the gene is strongly selected against in the normal light beige desert. Only when volcanic eruptions produced black volcanic rock was there a niche for the black mice to be selected for. What we see are islands of black mice in and around old black lava flows, surrounded by a sea of light beige mice.
The interesting part is that the black allele is dominant. However, you can't find black mice at any appreciable distance away from the black lava fields, which act as islands for the black allele. They were even able to show that there is free interbreeding between the black mice and the brown mice, but the black allele still doesn't spread far from the black volcanic islands in the light brown desert.
Just a moment...
What is also interesting is that the black lava flows are relatively recent compared to the much older light beige desert.
Edited by Taq, : No reason given.

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 Message 64 by Dr Adequate, posted 06-08-2016 2:02 PM Taq has replied

  
Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


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Message 61 of 76 (785633)
06-08-2016 12:13 PM
Reply to: Message 60 by Faith
06-06-2016 11:26 PM


I kept thinking of the pocket mice through this whole discussion too. Same situation.
Indeed, it is. In both situations we have a long history of strong negative selection against a dominant allele. This means that any mutations leading to dark coloration would be almost immediately eliminated from the population in past environments. Therefore, the mutations had to occur after the negative selective pressure was removed.
Do you agree?
Edited by Taq, : No reason given.

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 Message 67 by Faith, posted 06-08-2016 6:35 PM Taq has replied

  
Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


Message 63 of 76 (785639)
06-08-2016 12:27 PM
Reply to: Message 62 by jar
06-08-2016 12:22 PM


jar writes:
If such a mutation happened before the soot(lava) filled world the moth (mouse) would get eaten and so the trait, even though a dominate one, would not get passed on to future generations. The gene that would get passed to future generations would be the recessive one.
This is especially true of a dominant allele. Every individual carrying a single allele for dark coloration would experience negative selection. For a recessive gene, only individuals carrying two copies of the allele will experience negative selection. Recessive alleles will not be eliminated as quickly from a population, but given strong enough selective pressures they will be removed. As examples, there are many lethal recessive genetic diseases that are still circulating in the human population (e.g. Tay-Sachs disease).
Edited by Taq, : No reason given.

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Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


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Message 65 of 76 (785658)
06-08-2016 2:49 PM
Reply to: Message 64 by Dr Adequate
06-08-2016 2:02 PM


It is interesting to note from the paper that different populations of black mice have different genetic bases for their color.
Just as there is more than one way to skin a cat, there is more than one way to produce dark coloration. There are several different proteins and genes involved in the timing and extent of melanin production. Any one of those genes is a target for mutations that can change fur and skin coloration.
The fact that you have islands of black lava each with their population of mice with unique alleles is an indication that they evolved independently of one another and did not originate from a common mutation found in an ancestral population.

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Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


Message 73 of 76 (785937)
06-13-2016 3:22 PM
Reply to: Message 67 by Faith
06-08-2016 6:35 PM


I don't think this situation proves either the usual idea about mutations or the built-in allleles idea. Mutations are not supposed to come along on cue to meet a need, so there is something different going on here that has not been explained yet.
First, the idea of a pre-existing dark allele is thoroughly disproven. The allele would have been removed from the population in the absence of these lava fields due to negative selection. Therefore, it had to come about through mutation after the lava fields were produced by relatively recent volcanic eruptions.
Second, you haven't shown that it showed up on cue. There could have been hundreds of thousands of years between the volcanic eruptions and the occurrence of the mutation. You also haven't shown the rate at which the mutation appears in the absence of the black lava fields. What we do know is that the reason for the difference in fur color is mutations.

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Taq
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Posts: 10045
Joined: 03-06-2009
Member Rating: 5.3


Message 74 of 76 (785939)
06-13-2016 3:25 PM
Reply to: Message 69 by Faith
06-09-2016 12:07 PM


You are invited to do the probability calculations, but my rough guess is that to get a specific adaptive trait like a color that matches the background, you'd need something in the thousands or maybe millions of tries before it would show up.
As shown above, that is easily done in a mouse population. Even using your number of a million births in order to get one black mouse, that is easily done with even a small population of 10,000 mice. That is just 100 generations for a species with a 3 month generation time. That would be about once every 30 years, by my calculations.

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