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Author | Topic: Exposing the evolution theory. Part 2 | ||||||||||||||||||||||||||||||||||
WookieeB Member Posts: 163 Joined: |
How does it accumulate mutations?
Please, can you explain what is being searched for in an 'evolutionary' search? And how is that different from a random search?
No, I have no problem with the hill-climbing algorithm. It's not an issue of whether it can move up. It is an issue of whether it will move up. If you have a 1 in 10 chance to move up (where all the other 9 chances is not moving up), then it will only move up 1 in 10 tries. Now, if you are only allowed 2 tries, it is more likely to miss than to move up. No hill is climbed unless you happen to hit that '1' successful option.
Oh, so your hinging your statement on the "absolutely needed" part? You've got to be kidding me. Intuition, testing, and all experience indicates that mutating something is FAR, FAR more likely to break the thing being mutated than it is to help it. Even neutral changes would outnumber beneficial changes by a large factor. So mutations will heavily be tilted more to to break than to benefit. If you assume there are mutations that can benefit an organism, they will logically be far more specific than all other types of mutations.
What? Protein relation is irrelevant at this point. You have to explain how to get protein from RNA. There is a lot involved, including two separate code systems to create. You need to identify how RNA nucleotides form a digital code, how particular nucleotide sequences map to a particular amino acid, and then a system to marry the two together to form a protein chain. There are more critical pieces even than that, but just explain those 3. Any of three coming about by itself does nothing. You need all three together to function. There is a high level example of IC.
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WookieeB Member Posts: 163 Joined: |
So NS keeps a successful variant. Why? We would have to assume whatever you are constituting is a "variant" improves fitness. But NS cannot act on anything until the variant appears. So what is the probability of a variant appearing? NS cannot affect that probability. Which leads to....
Pardon??? Can you read that statement again and tell me you're serious?
No, you haven't explained the difference because I think you are confused over how a hill-climb actually searches. The only comment you made in trying to differentiate them was -
I didn't really notice it before, but you are not using consistent terms here when comparing both. When you mention hill-climbing, you said it "perturbs a parameter". No, it doesn't. In the context of what you are describing (the search itself), NS cannot do anything to a parameter, it cannot 'make' (perturb, influence, nudge, etc) a higher point into being. All it can do is wait for a search to reveal a higher point (and not necessarily the highest point to be found) and the lock that one in if found. The search process itself is RANDOM. The search process itself is mutations occurring. NS cannot affect what/where/how mutations occur. It is a wholly random process, thus the search itself is a RANDOM SEARCH. "A random search simply chooses completely random points until it hits the target" is true, which is what is going on with your hill search when it actually is searching. "...with no feedback at all." is a bit misleading, since a random search is looking for a target too (same as NS), and that is the feedback it gets.
But in many cases we do have the numbers. Like the malaria resistance to chloroquine. Without making unsubstantiated assumptions (like isolation) we can get a pretty good idea of the chances of new protein formation based on presumed times between ancestors. With orphan genes, you pretty much throw the isolation argument out the window, and you can estimate with a lot of wiggle room the likelyhood of genes appearing de novo. When it comes down to it, Darwinian processes do not have enough time or resources to do what it is claimed to have done.
Nobody is questioning that there may be multiple mutations vs one, or that there are multiple routes up the hill. It's not about the number so much as it is about the rarity of beneficial mutations. Take the malaria example again. It's acknowledged there are various ways resistance can occur. But the best chances for resistance is 10^20. That could possibly be due to a number of routes, but that number is still your floor. There is nothing to suggest that the chances are better than that. If that number can be taken in any way as an example of how Darwinian processes work in general (and there is no reason why it cannot), then it doesn't look good for the Darwinian paradigm to explain much.
I agree. And if that is the case, it doesn't provide much confidence in evolution to explain much. Edited by WookieeB, : No reason given.
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WookieeB Member Posts: 163 Joined: |
success = improved fitness. We're saying the same thing.
Ya, so what. Mutations happen. NS in a search cannot affect the rate, location, or type of mutation that occurs. It can only just view the mutation and do something AFTER a beneficial mutation occurs (assuming there is a beneficial mutation to be had - not a at a local peak or flat plateau). And depending on the landscape, the rate of mutation can limit what NS can do.
If not, you tell me what a random search is looking for. It has to have a target, all searches do.
....and then does what? I think you misunderstand what a random search is. It is not just picking some random point and moving there. That is a random move. That is NOT a search! A random search has a target like any search does. And what a random search is searching for in our context is "fitness" also. Same as your hill-climbing search. So what does a random search do when it finds fitness, it moves to that point and starts exploring, at random, again.
How does it "explore"? It looks in a random manner around it, just like in a random search. Random search is same as your hill-climbing search.
Ya, and it's incorrect because you are not characterizing a random search properly.
Mutating = perturbing. It's all random. So logically you must mean then that hill climbing is randomly changing the gene, which equates to a random search.
You cannot justify that. NS cannot affect the 'perturbation in any way. It has no influence. It can only move after it has evaluated a random change to see whether it is a successful hit or not. A random search does the same thing.
No! That is not what a random search is. What you just said is like morphing the landscape, then picking a random direction and moving that way. But in search, the landscape is static. The point you are starting form is the current state of things. A different point in the landscape is a different state of things, like a change to nucleotide(s) (mutation). A random search will look at a random point other than where it is, see whether it fits the search criteria, and either move or not move based on that criteria.
Same difference. Random Search
I do agree that Darwinian processes can explain some things in biology. But it cannot explain everything. Things categorized as microevolution - sure. But for the origins of life and macroevolution, which includes new proteins and body plans, IC structures, and all the new information that is required for them - Darwinism is not up to the task. And at least that is starting to be acknowledged by some the scientific community.
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WookieeB Member Posts: 163 Joined: |
Yes, in general I agree with you in this section. But we've been talking in terms of search. In a search, other points around a starting point are considered against a 'target' criteria. In the search context we are considering, NS has to evaluate a point presented to it. And what point(s) are presented to NS for evaluation is determined by the mutation process that you described. NS 'evaluates' the point based on the target criteria, which we have been generally referring to as "improved fitness" (or a "successful variant" that you quoted me on). NS then 'selects" the first target hit as presented to it. This evaluation and selection roughly equates to what you referred to later as "the "reproductive differential".
But it is important to understand generally the ratio of deleterious to neutral to beneficial mutations. By far, the majority seem to be deleterious. And it seems that beneficial is extremely rare. This fits with our intuition on things. When making random changes to a working system, it is much easier to break or blunt things than to improve them. The malaria resistance case is an good example. When a selective pressure was put on the malaria parasite, it showed a beneficial result (resistance) at a rate of 10^20. That number is based on empirical results, not probabilities of mutating the proteins. But when it was identified that at minimum, 2 specific point mutations (and possibly a third neutral one) were needed to confer some resistance, matching up the combinatorial options of the mutations with the 10^20 figure is not unreasonable. But in essence, what occurred was a breaking of a regulatory piece in the protein that allowed the protein to survive. When you then take the population of the malaria parasite in the relevant time and compare that to populations and time for eukaryote life forms (especially vertebrates), you run into resource limits that suggest similar beneficial mutation options would not be likely. Edited by WookieeB, : No reason given. Edited by WookieeB, : No reason given.
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WookieeB Member Posts: 163 Joined: |
Context!? Guess you don't know what that is. And your further comments suggest you have no concept of what 'search' is. OK, then..... By the way, if Natural Selection cannot do anything, why is the word "Selection" used at all?
Never said they acknowledged ID. Doesn't matter. What does matter is that they are questioning Darwinian processes. Why? Cause all the numbers and experiments and data show that it cannot do the big things it is claimed that it does. Edited by WookieeB, : No reason given.
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WookieeB Member Posts: 163 Joined: |
No objection here. Random search behaves exactly the same. The real number possibilities is where the question comes in. If NS only allows moves up, what happens if no up perturbation is presented to it?
Don't try to change the frame of reference on me. We've been couching this subject in the terms of 'Search'. In a search, there is ALWAYS a target.
So...then your hill-climb is the same as a random search. You haven't distinguished a difference.
Those are your statements. If you are suggesting that a random search randomizes the entire genome, you are incorrect. A random search just looks in a random direction from the current position. The closest point around it's current position corresponds to the simplest of changes, or a single point mutation. So that is no different than your 'evolution' search.
Interesting phrase - manage. What does that mean? As for creating those things, evolution cannot account for them. As for body plans, since it hasn't really been identified where the information for them resides, you cannot infer why evolution WOULD be able to manage them.
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WookieeB Member Posts: 163 Joined: |
You can equivocate all you want on the terms. 'Search" is a common explanatory analogy used by scientists to explain how changes in your "reproductive differential" happens. All searches have a target. In this case, the target is fitness, which come about by mutations (or other causes of change to the genome), and if beneficial may lead to a fixation in the population and ultimately lead to your reproductive differential. Cry all you want, but search is a commonly used idea in the literature.
So which is it? Nothing?.... A little?..... Often does? Obviously mutation rate can have some effect. I never stated how significant. That would depend I suppose on the rate on one item vs the rate on another. It's not equal across the board.
.... which is the landscape.
To some extent you are correct. Despite the change in positive-result rates, as long as the 2 fitness-increasing-fertility mutations appear, and assuming continued existence of the species, that's all you need. But note your numbers for this positive event. Even if we assume (as your example does) that the fixation is 100% guaranteed to spread given the appearance of the 2 beneficial mutations, you're showing mutation rates of 10000% (1x10^2) and 500% (5x10^1). That is nowhere near reality. For bacteria, the mutation rate is around 1x10^-8, and probably an order of magnitude less for eukaryotes. So ya, with a mutation rate 10-100 billion times more than normal, you're virtually guaranteed to see your 2-mutations-to-increased-fertility appear with a very modest population. But unfortunately for you, that is not realistic. Go to malaria resistance to chloroquine example. Despite how many varying paths that ultimately can lead to an increased-fertility situation, the odds still come out to 1x10^20 per individual for just needing a minimum of 2 specific point mutations occurring. Can you really expect the rest of life does better than those odds to accumulate what would have to be many, many mutations in concert?
Well, I would think it has to be both? If there are only 1 in 1 million rate of quality mutations out there in your mutation space (assuming 100% fixation), you'll probably progress if you have a million events. But what if you only have 10,000 events occurring. Then you probably wont have any progress. Realistic numbers are way worse than that.
Wow! So we actually can have an abstract description of NS to describe its effects as 'selecting' something. Go figure.
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WookieeB Member Posts: 163 Joined: |
"Darwinian processes", "Darwinism", "Neo-Darwinism", "Neo-Darwinian Synthesis" and "The Modern Synthesis" - are all colloquial terms to refer to the basically the same thing.
I'm not sure why you're so flustered by the term. Mayr, Gould, Marguilis, and many other all used the term(s).
Really? Go check out the review articles that the Royal Society put out. First article from Muller is pretty clear on the doubts for efficacy of the Modern Synthesis. https://royalsocietypublishing.org/...10.1098/rsfs.2017.0015 I'm in no way saying they are ready to take up the gauntlet of ID. Just pointing out that scientists are seeing the flaws in the traditional evolutionary view of M+NS.
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WookieeB Member Posts: 163 Joined: |
It's a very general idea. https://www.pnas.org/...nt/early/2014/07/08/1410107111.short http://science.sciencemag.org/content/261/5123/872 https://pdfs.semanticscholar.org/...8010e43d72b9dfb0d022.pdf https://pdfs.semanticscholar.org/...f43aea73e3c8e8581e9d.pdf https://medium.com/...-behind-genetic-algorithm-df75af08d5d6 https://www.pnas.org/...early/2016/08/04/1606195113.abstract Explaining general ideas of genetic algorithms Read a book - Look at what a Genetic Algorithm is.
So if NS doesn't do anything, why is it even mentioned with regards to evolution. How does it have anything to do with your "reproductive differential"? Why is it even named the way it is? "Natural Selection" as a term has nothing to do with accounting logs".
Yes I do. That would violate the laws of logic (PNC). It either does have an effect or it doesn't. It cannot be both.
The numbers matter. I'm sorry if you cannot handle realistic numbers, or even your own. That's your problem. The purpose of using an illustration is to relate it to things that are real or likely to be real. Your illustration wasn't. I pointed that out. I'm sorry that your fantasy situation wasn't logical, but that is not my problem.
LOL! Go re-read yourself! I asked how the word "selection", which by definition implies doing something, applies to the term 'Natural Selection" when you claim that 'Natural Selection' doesn't do anything. And you're response is that we can have abstract thoughts and say that NS is selecting mutations when it is actually doing no such thing and instead just keeping a ledger. Umm, ok. Still not logical, but if you say that the thing that evolutionary theory is hanging on is not doing anything, so be it. That's much more critical of the process (oh wait,,, non-process) than even I would say, but so be it.
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WookieeB Member Posts: 163 Joined: |
LOL!!! You're going to be the arbiter of what is a science term? You, who has problems with simple laws of logical thought? And then your example of an acceptable 'specific terms for quite specific items" is is "EVOLUTION"????? LOL!!! No! Please stop!!! My sides are hurting!!! Puhleazzzze! Darwinism is a common term used today. Even wikipedia acknowledges that. But even if we restrict it to the classic meaning (Darwin's time and forward till Mendelian genetics was used) it still encompasses the following: --More individuals are produced each generation than can survive. So, then according to you, "evolution" has no relation to the above?
(This section is a bit long, and deals with THIS article by Gerd Muller.) But I find it interesting, if "evolution" is so firmly established, why the need for changes? What you quoted from the article is fine, it just shows that the "theory of evolution" hasn't been able to keep up with modern data and needs refinement. I wish you had continued your quote. His very next sentences were: quote: And just to show that his view, of the standard evolutionary theory being in need of some serious changes (and just before he introduces his idea of the Extended Evolutionary Synthesis), is not some unique idea, he says: quote: And what are some of the problems with the theory? [I'm editing it a bit for the sake of space] - quote: and... quote: Did you not even read through his section 2? He talks about problems with a lot of the core MS ideas, like gradualism, adaptation, natural selection (which by the way he mentions does a lot more than just tally accounts), and how they're not standing up to more modern data and thinking. Here are a few other highlights. 1) How "evolution" is a variable term (in a manner just like I say 'Darwinian processes' are) - quote: ... and then he goes on to list 4 examples. 2) How criticism of evolution is usually taken (like on these forums) - quote: 3) How the concept of what I've been calling "search" is related to evolutionary theory. quote: Did you note words like "mathematical account" (that's numbers for you), "fitness landscapes", "algorithms". Go read it again. Maybe you will then understand why he and a lot of other scientists are looking for a Third Way apart from the Modern Synthesis/Neo-Darwinism
No. It obviously threw you though. LOL. The "pre-" stuff was before Darwin. Not Darwin's old stuff. Darwin's "post-" stuff, uses Darwin as the starting point and includes any related ideas of his up to today. Academically speaking. PRE means 'before', POST means after. Edited by WookieeB, : No reason given. Edited by WookieeB, : No reason given. Edited by WookieeB, : No reason given. Edited by WookieeB, : No reason given.
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WookieeB Member Posts: 163 Joined: |
So we see here a common tactic of evolution supporters on these forums. Make a general request - "Cite some literature treating NS as a "search";" When some literature is provided (not an exhaustive list by any measure), take just one of the multiple examples and focus on it. Focus how? By using an anecdotal example of someone doing something that is at best, just generally related but had a focus and hand in things other than biological systems. Then treat the results of this anecdotal example as directly relating to what the original topic was. And then the coup de grace?......
Ya, finally finish that strawman and set it on FIRE!!! Sorry. Doesn’t work. Now on to the NS definitions....
Yes, already acknowledged and understood. I'm also referring to NS in such a manner, the commonly understood manner where.....
Glad to see that NS actually does something, in the abstract way of thinking.
Yes! It is doing something again. Hallelujah! The whole process after the mutations occur, which includes the effect mutations have on the phenotype that leads to differential reproduction which leads to some versions becoming the dominant type (the being selected part).....that whole process in symbolic language is called NS. NS isn't just the spreadsheet, which you have been implying. It's the whole enchilada.
YES!!!! That "interface" is what I have been referring to, and what practically everyone else (including you outside of your need to restrict it to a spreadsheet) has been relating to when we say NS. In the symbolic language, in the abstract, in the analogous examples, in search algorithms - 'Natural Selection' selects!
I have no problem with what he called it or meant. You are the one with the semantic issues.
What an irrelevant statement. A mutation rate (other than zero) either has an effect or it doesn't. You seem to think it could be both at the same time.
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WookieeB Member Posts: 163 Joined: |
You're words that apply to "Evolution". And you don't see the discrepancy in those statements?
ROFLMAO! When AZPaul3 says "Let me paraphrase", you can take that to mean "Let me setup a strawman". You don't check your references very well. quote: And Eugenie Scott's beef with the term was that despite that "scientists and teachers use “Darwinism†as synonymous with evolutionary biology", she didn't like it because the term sometimes has ambiguous or bad connotations associated with it. You make it too easy. But if it really is a sore point for you, replace "evolution" with every instance I used "Darwinian processes" and I'll stand by it.
which I assume links to your "differential reproduction". And may I assume that your talk of "differential reproduction" is involved with "evolution"? I would hope that is a safe bet, since your phrase above about "making babies" was in reference to the concepts of - quote: ...which are the central ideas of Darwinism (yes, the classical, from Darwin himself - version). But wait!!! I guess now those concepts do NOT have anything to do with evolution. Since....
So, I guess you're saying that if those concepts, which would include differential reproduction and any concept of Natural Selection, are not part of "Evolution" (that term that is oh so specific and the only one authentically used by scientists),..... what exactly are you referring to when you say "Evolution"???? Really. If you want to equivocate on your terms, at least try to spread apart you're varying meanings by a few posts. Doing it all in the same post? You make it too easy.
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WookieeB Member Posts: 163 Joined: |
I'm tired of asking you if you understand logic, cause you evidently do not. So my asking: "Do you realize that a strawman is a logical fallacy, and you're cheering your strawman means your argument lacks merit?" So then...you using a strawman, which you just admitted to, is a logical fallacy, and that means your argument is without any logical merit.
Which cements that you still don't understand 'search'. In a search process, there is always a target. But that target may have nothing to do with how things move in a search space. In the case of a random search, and in the case of PaulK's search, the target does not have anything to do with how the search is performed. So the location of where a search looks, the accounting of YOUR description of NS, is randomly determined. So what is the target? It is that part of the accounting, or a very specific subset of your NS spreadsheet, that notes a movement 'up' the landscape. This all translates to a beneficial mutation occurring that leads to a more fit organism that is shown, accounted for, demonstrated, selected as..... "more babies". So essentially, in all these evolutionary searches that are being discussed, we do recognize that there will be cases of less babies, same number of babies, and more babies (in comparison to each other category). The more babies is really the only one we are concerned with, the target, because that corresponds to a forward move of evolution.
And yet you will proceed to do so over the next few paragraphs. But I especially like these two sentences - together at that....
So NS, in some manner, "selects". But in the same sentence, NS "does no such thing". Really??? LOL! Don't give this guy any more rope, please!
Thought you didn't like the numbers. You seem afraid of them. The NS numbers is what I have been using. Why can't you face them?
One or several, doesn't matter. It's irrelevant. Any mutation rate has an effect. You seem to be fighting that, and other than just to philosophically disagree with me, I can't figure why.
Ah, but "Darwin-anything" IS used as a synonym for TOE, Modern-Synthesis. "Neo-Darwinism" is explicitly a term that corresponds to the modern theory. Even your hero Mayr advocated that term. And do you really think you can say you don't like using any term like "Darwin-anything" and not be repudiating Darwin's related ideas? Are you serious?!? And you think I am the one being pedantic? And you think it is creationists that a quibbling over terms? Pot, meet kettle. LOL! And as I said, since it is YOU that is hung up about the wording, replace every prior instance where I said "Darwinian process(es)" with "evolution" and I am fine with it. As for Neo-Newtonianism being used in place of General Relativity, I would have no problem with that. If that was a common phrasing for the idea, why would I object? Edited by WookieeB, : No reason given. Edited by WookieeB, : No reason given.
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WookieeB Member Posts: 163 Joined: |
Sure, because you asked nicely. ![]()
No. They are not the same.
No. ID makes no attempt to identify the designer, it only infers there is a designing intelligence behind many of the features seen in nature. The designer could be the Christian God, a Hindu God, (in some contexts) a super-intelligent alien species, or any from a host of other potential intelligent entities (known or not) - but ID doesn't care. In other words, design is detectable by science, who the designer is is beyond science. I would assume that the method of design would involve some genetic engineering. I'm not sure what you mean by "guided evolution", as that term is somewhat an oxymoron, though that may depend on how you define "evolution".
That is a bit of a vague statement, but IMO that would not be an accurate characterization. Behe in the past has indicated agreement in the idea of Common Descent, but he does not subscribe to M+NS as the sole mechanism.
That might be true, but the statement is potentially a red-herring. I do know Behe is religious and does believe in God. But that is rather irrelevant for his ID position. In his ID writings, he doesn't try to identify the designer, he just infers there is one. So, as it would refer to ID, it might be more accurate to say 'he thinks that a designer had its fingers in the operation in some subtle* way'. * - "subtle" is a quantitative description that is as yet undefined, and it is not needed in the statement.
No. Design would be detectable, or at least inferred from the data. Standard evolutionary theory would not be the mechanism for bringing about many of nature's features.
Maybe, or maybe not. It is irrelevant to ID
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WookieeB Member Posts: 163 Joined: |
If you are asking about how "Design would be detectable", it is a technique that is used in other scientific endeavors. Information theory has a big hand in it, but design detection is used in Archaeology, Forensics, Crytography, search endeavors like SETI, and in many historical sciences. If you are asking about what Standard evolutionary theory can produce? It can produce some things very easily, but they are usually small changes that correspond to minor phenotypic traits, what is often referred to as micro-evolution. This is demonstrable, has an empirical justification, and ID doesnt dispute this kind of natural change. There are other features though that would be extremely difficult, if not practically impossible, for it to produce. Things that would be considered irreducibly complex would rarely, if ever, be able to be formed. Things like new body plans and regulatory networks. Anything that require an measure of complex and specified information have never been demonstrated to be formed via a random process, but in all cases where we do have knowledge of the origins, it has always been by a mind, intelligence. M + NS are just not up to the task of producing such things.
Yes, an old thread. From the OP, I can say there are some parts that I agree with, but I also was finding some things that are badly mis-characterized. On the whole, unfortunately, since I was finding many of the axioms put forward are not true, it ends up being a flawed argument.
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