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Author Topic:   Any practical use for Universal Common Ancestor?
edge
Member (Idle past 1706 days)
Posts: 4696
From: Colorado, USA
Joined: 01-09-2002


(3)
Message 1246 of 1385 (854785)
06-12-2019 6:10 PM
Reply to: Message 1244 by Dredge
06-12-2019 2:22 AM


Re: Another useful application of evolutionary theory
I can feel the pain and anguish of your confusion from here.
The only pain I'm aware of is from dying brain cells absorbing effluent emitted by anti-evolution posts.

This message is a reply to:
 Message 1244 by Dredge, posted 06-12-2019 2:22 AM Dredge has not replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1247 of 1385 (854926)
06-14-2019 3:20 AM
Reply to: Message 871 by JonF
05-08-2019 6:32 PM


JonF writes:
So this thread is pointless.
In retrospect, I should have asked for practical uses in applied science for the Darwinian (or neo-Darwinian) theory/explanation for the history of life on earth (as opposed to the theory of common descent).
(Someone (Stile, I think) implied that there might be such uses in "medicine" but I (my research team is on holidays at the moment) lost track of this part of the thread.)
P.S. Everyone who knows me says my whole life has been pointless from the very beginning, so I guess it's hardly surprising that I came up with what you perceive to be a "pointless" thread.
Edited by Dredge, : No reason given.
Edited by Dredge, : No reason given.
Edited by Dredge, : No reason given.

This message is a reply to:
 Message 871 by JonF, posted 05-08-2019 6:32 PM JonF has not replied

Replies to this message:
 Message 1248 by ringo, posted 06-14-2019 12:37 PM Dredge has replied
 Message 1249 by Taq, posted 06-14-2019 12:44 PM Dredge has replied

  
ringo
Member (Idle past 412 days)
Posts: 20940
From: frozen wasteland
Joined: 03-23-2005


Message 1248 of 1385 (854965)
06-14-2019 12:37 PM
Reply to: Message 1247 by Dredge
06-14-2019 3:20 AM


Dredge writes:
P.S. Everyone who knows me says my whole life has been pointless from the very beginning, so I guess it's hardly surprising that I came up with what you perceive to be a "pointless" thread.
Well, you have a nice avatar.
Edited by ringo, : Fixed quote.

All that are in Hell, choose it. -- CS Lewis
That's just egregiously stupid. -- ringo

This message is a reply to:
 Message 1247 by Dredge, posted 06-14-2019 3:20 AM Dredge has replied

Replies to this message:
 Message 1250 by Dredge, posted 06-19-2019 10:08 PM ringo has seen this message but not replied

  
Taq
Member
Posts: 9972
Joined: 03-06-2009
Member Rating: 5.5


(2)
Message 1249 of 1385 (854967)
06-14-2019 12:44 PM
Reply to: Message 1247 by Dredge
06-14-2019 3:20 AM


Dredge writes:
(Someone (Stile, I think) implied that there might be such uses in "medicine" but I (my research team is on holidays at the moment) lost track of this part of the thread.)
Conservation and overall evolution of gene sequences between species is being leveraged to study human genetic diseases:
quote:
Data on replacement mutations in genes of disease patients exist in a variety of online resources. In addition, genome sequencing projects and individual gene sequencing efforts have led to the identification of disease gene homologs in diverse metazoan species. The availability of these two types of information provides unique opportunities to investigate factors that are important in the development of genetically based disease by contrasting long and short-term molecular evolutionary patterns. Therefore, we conducted an analysis of disease-associated human genetic variation for seven disease genes: the cystic fibrosis transmembrane conductance regulator, glucose-6-phosphate dehydrogenase, the neural cell adhesion molecule L1, phenylalanine hydroxylase, paired box 6, the X-linked retinoschisis gene and TSC2/tuberin. Our analyses indicate that disease mutations show definite patterns when examined from an evolutionary perspective. Human replacement mutations resulting in disease are overabundant at amino acid positions most conserved throughout the long-term history of metazoans. In contrast, human polymorphic replacement mutations and silent mutations are randomly distributed across sites with respect to the level of conservation of amino acid sites within genes. Furthermore, disease-causing amino acid changes are of types usually not observed among species. Using Grantham’s chemical difference matrix, we find that amino acid changes observed in disease patients are far more radical than the variation found among species and in non-diseased humans. Overall, our results demonstrate the usefulness of evolutionary analyses for understanding patterns of human disease mutations and underscore the biomedical significance of sequence data currently being generated from various model organism genome sequencing projects.
Understanding human disease mutations through the use of interspecific genetic variation | Human Molecular Genetics | Oxford Academic

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 Message 1247 by Dredge, posted 06-14-2019 3:20 AM Dredge has replied

Replies to this message:
 Message 1251 by Dredge, posted 06-20-2019 7:04 PM Taq has replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1250 of 1385 (855454)
06-19-2019 10:08 PM
Reply to: Message 1248 by ringo
06-14-2019 12:37 PM


ringo writes:
Well, you have a nice avatar.
Merci beaucoup. Your kind words are appreciated. Dredges (the machines) are truly lovely things.
Edited by Dredge, : No reason given.

This message is a reply to:
 Message 1248 by ringo, posted 06-14-2019 12:37 PM ringo has seen this message but not replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1251 of 1385 (855599)
06-20-2019 7:04 PM
Reply to: Message 1249 by Taq
06-14-2019 12:44 PM


That's all fine and dandy, but I fail to see how it demonstrates that accepting the Darwinian explanation is necessary to utilize knowledge of genetics in a practical sense. Are you saying a YEC biologist couldn't understand the genetics of extant organisms?
Edited by Dredge, : No reason given.

This message is a reply to:
 Message 1249 by Taq, posted 06-14-2019 12:44 PM Taq has replied

Replies to this message:
 Message 1252 by edge, posted 06-21-2019 6:05 PM Dredge has replied
 Message 1253 by Taq, posted 06-24-2019 6:38 PM Dredge has replied

  
edge
Member (Idle past 1706 days)
Posts: 4696
From: Colorado, USA
Joined: 01-09-2002


(3)
Message 1252 of 1385 (855692)
06-21-2019 6:05 PM
Reply to: Message 1251 by Dredge
06-20-2019 7:04 PM


That's all fine and dandy, but I fail to see how it demonstrates that accepting the Darwinian explanation is necessary to utilize knowledge of genetics in a practical sense. Are you saying a YEC biologist couldn't understand the genetics of extant organisms?
If the concept of a common ancestor is used by just one scientists to make sense of life on earth, then it is useful. Period.
I don't care that it is necessary or not, nor if YECs might understand genetics. This entire thread has been a specious argument based on one person's rather limited opinion.

This message is a reply to:
 Message 1251 by Dredge, posted 06-20-2019 7:04 PM Dredge has replied

Replies to this message:
 Message 1254 by Dredge, posted 06-24-2019 10:37 PM edge has replied

  
Taq
Member
Posts: 9972
Joined: 03-06-2009
Member Rating: 5.5


Message 1253 of 1385 (855925)
06-24-2019 6:38 PM
Reply to: Message 1251 by Dredge
06-20-2019 7:04 PM


Dredge writes:
That's all fine and dandy, but I fail to see how it demonstrates that accepting the Darwinian explanation is necessary to utilize knowledge of genetics in a practical sense.
Then why did you ask for practical uses for UCA?
Are you saying a YEC biologist couldn't understand the genetics of extant organisms?
Can you show me a YEC biologists who can predict which regions in a genome have function by using comparative genomics?

This message is a reply to:
 Message 1251 by Dredge, posted 06-20-2019 7:04 PM Dredge has replied

Replies to this message:
 Message 1255 by Dredge, posted 06-24-2019 10:39 PM Taq has replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1254 of 1385 (855936)
06-24-2019 10:37 PM
Reply to: Message 1252 by edge
06-21-2019 6:05 PM


edge writes:
If the concept of a common ancestor is used by just one scientists to make sense of life on earth, then it is useful.
Irrelevant to the OP

This message is a reply to:
 Message 1252 by edge, posted 06-21-2019 6:05 PM edge has replied

Replies to this message:
 Message 1264 by edge, posted 06-26-2019 11:55 AM Dredge has replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1255 of 1385 (855937)
06-24-2019 10:39 PM
Reply to: Message 1253 by Taq
06-24-2019 6:38 PM


In other words, you can't provide a practical use in applied science for the Darwinian explanation for the fossil record.

This message is a reply to:
 Message 1253 by Taq, posted 06-24-2019 6:38 PM Taq has replied

Replies to this message:
 Message 1256 by Pressie, posted 06-25-2019 4:55 AM Dredge has not replied
 Message 1258 by Taq, posted 06-25-2019 11:27 AM Dredge has replied

  
Pressie
Member
Posts: 2103
From: Pretoria, SA
Joined: 06-18-2010


(3)
Message 1256 of 1385 (855945)
06-25-2019 4:55 AM
Reply to: Message 1255 by Dredge
06-24-2019 10:39 PM


Dredge writes:
In other words, you can't provide a practical use in applied science for the Darwinian explanation for the fossil record.
I can. The very idea of it pisses creationists off. That's more than enough practical use for me!
Edited by Pressie, : No reason given.

This message is a reply to:
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Sarah Bellum
Member (Idle past 595 days)
Posts: 826
Joined: 05-04-2019


Message 1257 of 1385 (855967)
06-25-2019 8:44 AM
Reply to: Message 1071 by Dredge
05-26-2019 10:26 PM


I didn't say that the OP took the attitude that "practical" is the only measure of the need for knowledge. But the OP does begin with "I've been looking for a practical use in applied science for the information..." And you, of course, just wrote, "...no practical yet..."
The idea of a universal common ancestor is a concept in a branch of science with enormous practical applications. If you look it up, you'll find applications to patterns of disease mutation, relative virulence of parasites, handling drug or pesticide resistance, selective breeding ("artificial" selection finds knowledge of "natural" selection useful!), evaluation of possible hazards from genetically modified crops, preservation of endangered species, understanding of gene function (if you know the pattern of descent it helps in learning about genes with still-unknown function), development of biological strains to decompose hazardous materials, genetic algorithms . . .

This message is a reply to:
 Message 1071 by Dredge, posted 05-26-2019 10:26 PM Dredge has replied

Replies to this message:
 Message 1260 by Dredge, posted 06-26-2019 12:41 AM Sarah Bellum has replied

  
Taq
Member
Posts: 9972
Joined: 03-06-2009
Member Rating: 5.5


Message 1258 of 1385 (855981)
06-25-2019 11:27 AM
Reply to: Message 1255 by Dredge
06-24-2019 10:39 PM


Dredge writes:
In other words, you can't provide a practical use in applied science for the Darwinian explanation for the fossil record.
I already supplied that practical use.

This message is a reply to:
 Message 1255 by Dredge, posted 06-24-2019 10:39 PM Dredge has replied

Replies to this message:
 Message 1259 by Dredge, posted 06-26-2019 12:37 AM Taq has replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1259 of 1385 (856059)
06-26-2019 12:37 AM
Reply to: Message 1258 by Taq
06-25-2019 11:27 AM


Taq writes:
I already supplied that practical use.
The practical use you supplied involves information relating to extant organisms - in other words, a biologist could believe the world is a hundred years old and still gain and use that information. So the "information" that life on earth is the result of Darwinian evolution is completely irrelevant to gaining and using the genetic information you mentioned.

This message is a reply to:
 Message 1258 by Taq, posted 06-25-2019 11:27 AM Taq has replied

Replies to this message:
 Message 1265 by Taq, posted 06-26-2019 1:58 PM Dredge has replied

  
Dredge
Member
Posts: 2850
From: Australia
Joined: 09-06-2016


Message 1260 of 1385 (856060)
06-26-2019 12:41 AM
Reply to: Message 1257 by Sarah Bellum
06-25-2019 8:44 AM


Sarah Bellum writes:
The idea of a universal common ancestor is a concept in a branch of science with enormous practical applications. If you look it up, you'll find applications to patterns of disease mutation, relative virulence of parasites, handling drug or pesticide resistance, selective breeding ("artificial" selection finds knowledge of "natural" selection useful!), evaluation of possible hazards from genetically modified crops, preservation of endangered species, understanding of gene function (if you know the pattern of descent it helps in learning about genes with still-unknown function), development of biological strains to decompose hazardous materials, genetic algorithms . . .
. all this information would have be gained and these uses would have been developed if everyone believed life on earth was 100 years old - which means the Darwinian explanation for the history of life on earth is completely irrelevant to them.
Edited by Dredge, : No reason given.
Edited by Dredge, : No reason given.
Edited by Dredge, : No reason given.

This message is a reply to:
 Message 1257 by Sarah Bellum, posted 06-25-2019 8:44 AM Sarah Bellum has replied

Replies to this message:
 Message 1261 by AZPaul3, posted 06-26-2019 1:57 AM Dredge has not replied
 Message 1263 by ringo, posted 06-26-2019 11:44 AM Dredge has not replied
 Message 1266 by Sarah Bellum, posted 06-27-2019 10:50 AM Dredge has replied

  
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