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Author Topic:   Needed: Info on Human/Chimp ERV's
Loudmouth
Inactive Member


Message 1 of 6 (102252)
04-23-2004 5:49 PM


I am planning on starting a thread on ERV's as evidence of human and chimp/gorilla common ancestory within the next week. If anyone has info on this, please post it here. This thread is not meant as a debate on the issue, only as a repository for online information pertaining to human ERV's. All types of resources, including those that attempt to refute human/chimp common ancestory, are welcome.
Specifically, I am looking for:
--Specific placement of ERV's within genomes.
--Mutational analysis
--Arguments pertaining to the randomness of viral insertion.
--Possible ERV role in gene regulation.
Thanks.

Replies to this message:
 Message 3 by Mammuthus, posted 04-26-2004 4:20 AM Loudmouth has replied

  
Mike
Inactive Member


Message 2 of 6 (102340)
04-23-2004 11:48 PM


Loudmouth,
A while back I found an online creationist piece that cites some ERV (HERV-K) data to refute evolution. The article is a bunch of quotes and citations taken completely out of context, with the argument being something along the lines of if scientists can not define with extreme precision exactly how similar humans and chimps are (is it 98.4%? or 97.6%?), then evolution must be false. Anyway, the article discusses human evolution, creationism, and HERVs so it fits your query. it is here: Page not found - Apologetics Press
more later,
Mike

  
Mammuthus
Member (Idle past 6583 days)
Posts: 3085
From: Munich, Germany
Joined: 08-09-2002


Message 3 of 6 (102748)
04-26-2004 4:20 AM
Reply to: Message 1 by Loudmouth
04-23-2004 5:49 PM


quote:
human and chimp/gorilla common ancestory
Barbulescu, M., G. Turner, M.I. Seaman, A.S. Deinard, K.K. Kidd, and J. Lenz. 1999. Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. Curr Biol 9: 861-868.
Barbulescu, M., G. Turner, M. Su, R. Kim, M.I. Jensen-Seaman, A.S. Deinard, K.K. Kidd, and J. Lenz. 2001. A HERV-K provirus in chimpanzees, bonobos and gorillas, but not humans. Curr Biol 11: 779-783.
quote:
Possible ERV role in gene regulation
Blaise, S., N. de Parseval, L. Benit, and T. Heidmann. 2003. Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution. Proc Natl Acad Sci U S A 100: 13013-13018.
Samuelson LC, Phillips RS, Swanberg LJ.
Amylase gene structures in primates: retroposon insertions and promoter evolution.
Mol Biol Evol. 1996 Jul;13(6):767-79.
quote:
Mutational analysis
Bosch E, Jobling MA.
Duplications of the AZFa region of the human Y chromosome are mediated by homologous recombination between HERVs and are compatible with male fertility.Hum Mol Genet. 2003 Feb 1;12(3):341-7.
Landry JR, Rouhi A, Medstrand P, Mager DL.
The Opitz syndrome gene Mid1 is transcribed from a human endogenous retroviral promoter.
Mol Biol Evol. 2002 Nov;19(11):1934-42.
Guasch G, Popovici C, Mugneret F, Chaffanet M, Pontarotti P, Birnbaum D, Pebusque MJ. Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem-cell myeloproliferative disorder with t(8;19)(p12;q13.3).Blood. 2003 Jan 1;101(1):286-8. Epub 2002 Jun 28.
quote:
Arguments pertaining to the randomness of viral insertion.
Lapuk AV, Khil PP, Lavrentieva IV, Lebedev YB, Sverdlov EDA human endogenous retrovirus-like (HERV) LTR formed more than 10 million years ago due to an insertion of HERV-H LTR into the 5' LTR of HERV-K is situated on human chromosomes 10, 19 and Y.
J Gen Virol. 1999 Apr;80 ( Pt 4):835-9.
Voisset C, Bouton O, Bedin F, Duret L, Mandrand B, Mallet F, Paranhos-Baccala G.
Chromosomal distribution and coding capacity of the human endogenous retrovirus HERV-W family.
AIDS Res Hum Retroviruses. 2000 May 20;16(8):731-40.
Reus K, Mayer J, Sauter M, Scherer D, Muller-Lantzsch N, Meese E.
Genomic organization of the human endogenous retrovirus HERV-K(HML-2.HOM) (ERVK6) on chromosome 7.
Genomics. 2001 Mar 15;72(3):314-20.

This message is a reply to:
 Message 1 by Loudmouth, posted 04-23-2004 5:49 PM Loudmouth has replied

Replies to this message:
 Message 4 by NosyNed, posted 04-26-2004 11:55 AM Mammuthus has not replied
 Message 5 by Loudmouth, posted 04-26-2004 7:41 PM Mammuthus has replied

  
NosyNed
Member
Posts: 9007
From: Canada
Joined: 04-04-2003


Message 4 of 6 (102791)
04-26-2004 11:55 AM
Reply to: Message 3 by Mammuthus
04-26-2004 4:20 AM


Good to see you again, Mammuthus
But I don't get the point of your post.
added by edit
sorry, yes I do
[This message has been edited by NosyNed, 04-26-2004]

This message is a reply to:
 Message 3 by Mammuthus, posted 04-26-2004 4:20 AM Mammuthus has not replied

  
Loudmouth
Inactive Member


Message 5 of 6 (102901)
04-26-2004 7:41 PM
Reply to: Message 3 by Mammuthus
04-26-2004 4:20 AM


Mammuthus,
Long time, no see. When I wrote the OP I had you in mind, but felt a little depressed because I hadn't seen you around for a while. Thanks for the refs, it looks like I have my work cut out for me. Been a while since I wrote anything resembling a review paper, much less a version for general consumption.
And thanks to Mike as well. All evidence is welcome, and I will try to incorporate the creationist/apologetic criticisms.

This message is a reply to:
 Message 3 by Mammuthus, posted 04-26-2004 4:20 AM Mammuthus has replied

Replies to this message:
 Message 6 by Mammuthus, posted 04-27-2004 5:28 AM Loudmouth has not replied

  
Mammuthus
Member (Idle past 6583 days)
Posts: 3085
From: Munich, Germany
Joined: 08-09-2002


Message 6 of 6 (103006)
04-27-2004 5:28 AM
Reply to: Message 5 by Loudmouth
04-26-2004 7:41 PM


Around but not back
Hi Loudmouth,
There is a textbook on all things HERV coming out soon but I don't think it hit the market yet. If you go to PubMed, look up Lwer R and you will also get a bunch of review articles on HERVs, though they are a bit dated. Not exactly a ton of us working on the subject
Unfortunately because of time constraints I will continue to be in lurker mode (so I can't cure your depression ). Also, the new overwhelming Administrator control and intrusiveness I find is stifling debate, driving some of my favorite people off the site (or at least shutting down their participation), and generally lowering the quality of the forum. So I still feel no reason to post..at least not regularly anymore. When I stated that I felt the coddling of creationists was an error, Moose made it clear where I could stick my opinion, so...I left/became a lurker....but your request for information was something I could not resist (though I almost could not post it since I could not remember my password anymore )..I am writing a paper on a very similar subject..most of the references were right in front of me
cheers and keep up the good fight
M
[This message has been edited by Mammuthus, 04-27-2004]

This message is a reply to:
 Message 5 by Loudmouth, posted 04-26-2004 7:41 PM Loudmouth has not replied

  
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