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Author Topic:   Intelligent Design in Universities
Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 176 of 310 (205712)
05-06-2005 6:56 PM
Reply to: Message 175 by Jerry Don Bauer
05-06-2005 6:33 PM


I'm trying to understand here, why does something being random mean it has to be equiprobable? Can't the probability of something be impossible to calculate (and thus random according to yourself) but simply more likely to occur than something else?
Now is there anyone you know who can sit down and calculate the probabilities of what will mutate the next time an organism reproduces? No. Therein lies the answer. They ARE random.
An illustrative example: If I have two dice, one has 6 sides, the other has 100. They are both random, but the chances of either one rolling a '4' is not equiprobable is it? Naturally, we can sit down and calculate the probabilities in this case, so to make it better, how about we use dice with a random number of sides (equal to or greater than 4)? Are they equiprobable now?
Please, tell me if I am misrepresenting you here.

This message is a reply to:
 Message 175 by Jerry Don Bauer, posted 05-06-2005 6:33 PM Jerry Don Bauer has replied

Replies to this message:
 Message 177 by Jerry Don Bauer, posted 05-06-2005 7:12 PM Modulous has replied

Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 179 of 310 (205728)
05-06-2005 7:28 PM
Reply to: Message 177 by Jerry Don Bauer
05-06-2005 7:12 PM


I would certainly enjoy you being in my craps game! This does not relate to the discussion, IMHO, because your die do not have the same number of sides and therefore are not equiprobable. There are exactly 4 bases that form the codons in DNA. Any of these bases can mutate, so is one base more probable to mutate than another? I don't think so and I would have to see the math and what it based on before I would be convinced otherwise.
OK, good I'm not going crazy. This basically is a respsonse to your dismissal of Message 134. It seems to me that certain phenemenon can 'load the dice', or to quote one of the abstracts:
quote:
Mutation frequencies vary significantly along nucleotide sequences such that mutations often concentrate at certain positions called hotspots.
The term 'mutation frequencies vary' seems to me to be saying that mutation probabilities aren't equiprobable.
  1. Have I interpreted the abstract correctly?
  2. Do you agree with the abstract?
**********edit*************
At first I didn't understand what you meant when you said:
I don't see how. We have PhDs that do this kind of math...I would see no cases where probabilities cannot be calculated when probabilities are known to occur.
in response to my question "Can't the probability of something be impossible to calculate but be simply more likely to occur than something else?" I understand why I'm confused now. It lies in your earlier statement:
Now is there anyone you know who can sit down and calculate the probabilities of what will mutate the next time an organism reproduces? No. Therein lies the answer. They ARE random.
You seemed to be implying that since someone cannot calculate a probability it must be random. Am I right? The problem of course, is that you then say that we have eggheads that can do the math, and that (as far as you know) probabilities are calcuable if we know probabilities occur.
So either you made a slip up, which is fine, I understand, no problem. Or there isn't a probability involved in mutations, which seems odd to me. Perhaps there is another option I haven't perceived?
********end edit*********
This message has been edited by Modulous, 05-06-2005 07:37 PM
This message has been edited by Modulous, 05-06-2005 07:39 PM

This message is a reply to:
 Message 177 by Jerry Don Bauer, posted 05-06-2005 7:12 PM Jerry Don Bauer has replied

Replies to this message:
 Message 180 by Jerry Don Bauer, posted 05-06-2005 7:44 PM Modulous has not replied
 Message 183 by Brad McFall, posted 05-06-2005 7:55 PM Modulous has not replied
 Message 185 by Jerry Don Bauer, posted 05-06-2005 10:00 PM Modulous has replied

Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 195 of 310 (205831)
05-07-2005 10:55 AM
Reply to: Message 185 by Jerry Don Bauer
05-06-2005 10:00 PM


I don't know if I agree with the abstract, because I cannot get past the abstract to find the paper.
Fair enough, you just seemed overly dismissive of it in 'tone' and I wondered why.
To me, unknown probability seems an oxymoron. How can something be said to have a probability of happening when we don't know enough about the probability to calculate it? How then, would we even know it is probable to begin with?
I don't know it depends on how we define our terms I suppose. I could say that there is no probability in horse racing. After all, if we can know all the information about any situation we can deduce who has to win. Unfortunately to do that we have to pull together an obscene amount of information, including the thoughts and memories of all the racers and the horses. In this case calculating who will win is done on probabilities based on what is known, but we cannot calculate the exact probabilities. Hence, our probabilities are unknown.
Is the winner of a horse race random? Not really, its just so complicated as to be inherently unpredictable. When some thing is unpredictable the results might appear to be random, but just be due to incomplete information.
DNA mutation surely comes under this definition of random? I'm sure quantum uncertainty will play its part to ensure true randomness, it will be insignificant compared with larger factors such as the presence of strong radioactive sources.
Am I barking up the wrong tree here? I think what I am saying is that DNA mutation is unpredictable but its not arbitrarily random.
Incidentally, I'm not trying to debate your central theme here, I'll leave that to others who understand (or not depending on opinion) the subject better than I. I appreciate that it might be that, on average, it is as good as totally random.

This message is a reply to:
 Message 185 by Jerry Don Bauer, posted 05-06-2005 10:00 PM Jerry Don Bauer has replied

Replies to this message:
 Message 208 by Jerry Don Bauer, posted 05-07-2005 6:09 PM Modulous has replied

Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 210 of 310 (205910)
05-07-2005 6:20 PM
Reply to: Message 208 by Jerry Don Bauer
05-07-2005 6:09 PM


Probabilities are known, but probabilities are not sure things or they wouldn't be probabilities. How do you think the bookies make money on horse races?
Well obviously. What I was saying was, that a bookie can't predict the exact probability of a horse winning a race, but we assume that a horse has a probability of winning.
Let's forget random and go to the word spontaneous, which in chemistry means something that will happen without a cause, with no inputted energy--for no reason. Some mutations are not spontaneous because they are caused to happen by mutagens--radiation, carcinogens, etc. But by and large, most mutations are spontaneous which means they just happen. And things that just happen are not predictable.
Excellent word 'spontaneous', that clears things up a lot, thank you. May I ask though: Are these mutations spontaneous in the same way that a radioactive nucleus decaying at any given moment is spontaneous, or is it spontaneous in that it has a cause, but its impossible to isolate what that cause is?
This message has been edited by Modulous, 05-07-2005 06:20 PM

This message is a reply to:
 Message 208 by Jerry Don Bauer, posted 05-07-2005 6:09 PM Jerry Don Bauer has replied

Replies to this message:
 Message 239 by Jerry Don Bauer, posted 05-07-2005 11:13 PM Modulous has not replied

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