In my opinion. Everything affects everything. The big bang effects my wardrobe decision this morning to wear a suede jacket. The determistic effects of physics are undeniable on future events. However things can happen and play out in a myriad of ways all dependent on cascades of other outcomes. In short we are who our brain is. Our brain is a product of both nature and nurture. Those things shape our minds and personalities. If someone has a sick brain then He will possibly do sick things. But that does not mean someone born with deficits can not overcome them.