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Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
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Author | Topic: Life - an Unequivicol Definition | |||||||||||||||||||||||||||||||||||
AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Genomicus writes: An absurdly tautological statement. "This definition of life...covers all known life." The perisylvian areas of my brain feel like bursting at this egregiously tautological statement. No -- what your definition covers is an arbitrary portion of the natural world, which presumably fits some pragmatic objective. Maybe you ought to try and understand what a tautology is before you accuse some one of creating a tautology. Definitions are not tautologies. Definitions should always be true for the word they are defining. A definition describes the meaning of a word. If the word is readily used in the language then the definition should apply to how that word is used in the language .ie "all known life"
Gen writes: 1. How many ATP molecules must be consumed in order for a self-contained entity to be considered alive? You may think this is an irrelevant question. It is not, because some biological entities need not consume any ATP at all, and some consume different and varying levels of ATP molecules. Your definition requires ATP consumption -- but how much and to what extent? Enough ATP to metabolize the synthesis of the enzymes required for the synthesis of the ATP. Definitely more than one molecule.
Gen writes: 2. Why do you have the requirement for genetic transfer from DNA to RNA? What is your non-tautological reason for stipulating this requirement? Because there a basically two camps of thought within OOL. One is metabolism first, and the other is genetics first. The RNA world is the genetics first camp. My definition covers both, because both are in all known cellular life. I am amazed that you challenge this as arbitrary. This definition is the furthest thing from arbitrary. So this definition requires the genetic transfer of information from DNA to RNA to proteins to synthesize at a minimum the enzymes necessary to synthesize the ATP necessary to metabolize.
Gen writes: Because living things need catalysts to speed up the chemical reactions. In the synthesis of ATP, those catalysts are enzymes. Certainly living things do a whole lot more than this, but this level of complexity is the minimal amount that a cell could be called "living"
3. It must be a "protein factory," you say. But why? What is uniquely special about amino acid chains that somehow gives "life" to something? Why did you choose protein production, and not lipid production? Or carbon production? Gen writes: Au contraire! It is 100% measurable. All facets of the definition. Therefore it is rigorous.
No -- your definition isn't any more rigorous and "measurable" than other definitions of "life."
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Cat Sci writes: Look at this image:
I can point to the middle of it and say that it is not black. But nobody can say where white stops and black starts. Well not to make a big deal about this, but it is done all the time. There is black paint, and there is white paint. Grey is a mixture of the two.
Cat Sci writes: Well No! Either you drastically misunderstand or this is a severe strawman. Let's examine your example. You're insisting that only the far right edge be called black, and everything else besides that be called white. Denying the existence of all that grey space is a disservice to everyone. Why do you insist on it? Let's say since black symbolically represents death, that black is dead stuff. Since white is the combo of all colors, let's say that that is life! Anything white is cellular life which is uncontroversial, unequivocal, and meets most if not all of the seven characteristics of life. Now to the naked eye, one cannot differentiate white from grey for about 10% of the gradient on the left side. It all looks white! The same is true for about 10% of the gradient on the right side. That leaves about 80% which is some shade of grey. My definition is on the grey side of white. It is not 100% white, but very close, and within the 10% gradient line as an analogy. It is a minimalist definition of life. So I disagree with your statement that I am denying the "grey gradient" of life. However, I am saying that "white" (10% margin) and Black (10% margin) is not so fuzzy, and it is definable. Now let's look at some examples with the current 7 characteristics of Life that are in most Biology textbooks: 1. Homeostasis2. Metabolism 3. Growth 4. Adaptation 5. Response to stimuli 6. Reproduction 7. Organization / Cellular Self replicating molecules - 2 and 6 and 4?Fire - 2 and 3 and 4? and 5? and 6? Crystals - 3 and 6 virions - 7 The only reason "life is fuzzy" is because of the equivocal terms used to define it. With my definition, only one of these terms is used in a very specific way. My definition allows all of these characteristics, but requires a certain minimal level of self sustainment which is identifiable in living things. No equivocation needed. My definition does not remove the grey, but it limits what can be identified as white.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Dr. A writes: Part 1 Well, I can see some problems with your definition. Hypothetically, suppose we met a bunch of intelligent space aliens that could discuss poetry with us and play chess with us, but had a different basis for their biology, no DNA, no ATP. According to your definition, they're not alive. They're not as alive as a bacterium. They're as alive as a rock, i.e. not alive. They don't use ATP. But surely a definition of life should include them? Why? They are imagination. They are fiction. What scientific principle requires such an inclusion?
Dr. A writes: By analogy, imagine an island where a bunch of white people live, and where all the animals are black. Now, these islanders might come up with a definition of human that says: "Humans are white, anything that's black is a mere animal". But their definition is parochial, it only works for their particular island in the particular time that they're inhabiting it. A definition of life has to include everything that we'd acknowledge as being alive if we saw it. And keeping with your example, once the definition no longer works, it must be abandoned or modified. No big deal. "Science" does posit the theory of panspermia though doesn't it. And within that theory, the life that is seeded on this earth is what we currently identify as organic life. No need to deal with fiction or imagination. "science" is about knowing, and we know what life is. Therefore we can define it.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Percy,
This just isn't so. Someone asked about a mitochondria. It meets my definition! It's part of endosymbiotic theory. I don't know of any that can survive outside of a cell. But a functioning mitochondria outside of a eukayrotic cell would be alive according to my definition, and I would be quite happy with that. A definition is to create the description that differentiates living organisms from other chemical arrangements. I chose the simplest arrangement that includes the production of metabolic molecules and the production of the enzymes required for their synthesis. A mitochondria's DNA level is much smaller than the entire cell's. You completely ignored my application of virions, fire , crystals, and self-replicating molecules. All of which fall into the grey area somewhere. Call them fuzzy if you want, but the consensus agrees that none of these are alive. So there must be a recognition that there is some minimal level to be called life. You cannot intelligently argue that this minimal requirement doesn't exist long before this discussion began. What you and others are wanting to do is say that life is a continuum from chemicals to life, and that is a faith based premise that I do not accept. It ignores the many things in life that are not chemical. ie organization, architecture or shape, electromagnetic radiation, and gravity. ( none of which are chemical) And finally, any good definition of life must also identify it's opposite (or death). Life is not the continuum. Death is. So I have used the analogy properly. That is of course if you think you can define death for us chemically?
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
RAZD writes: (1) It doesn't address the issue of viral life, which is increasingly being accepted as life forms as more is found out (self replication without host, metabolism and making of proteins used to encase it, etc) You have claimed this several times now. Admittedly, I am totally unaware of this. Evidence Please! Hopefully papers I can access on the web. Not journalistic articles I hope.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Mr J writes: Seems to me that's exactly what a good scientific definition would be
rather it's an observation of features of most known life. A good definition of life would describe what life is.. Mr J writes: Let us suppose that we travel to the planet Delton-Four and there discover "plants" that grow in sunlight and "animals" with fur and wings and teeth and legs that move around and eat the "plants". Would you not call this life? I would. In fact, I'd say it's a lot more unambiguously life than some things your definition includes. Yet, if this new "life" uses PNA instead of DNA or carries energy on TTP or synthesizes directly from DNA or uses a sDNA intermediate instead of an sRNA intermediate then you'll declare it "not life". Well when you get there, let me know and we can write a paper on it. Why not suppose a planet where water is HeO2? Diamonds are made from lead? we would still call the diamonds and water, right? Do you see any difference in "supposing an imaginary" observation, and real observations? I guess not.
Mr J writes:
So a good definition is based on imaginary observations and a poor definition is based on actual observation? Wait , that's mom calling from Delton-Four, I'll have to call you back. LOL A poor definition indeed. Edited by AlphaOmegakid, : No reason given.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Ringo writes: A good definition, like a good theory, should be able to accommodate new information. I have no problem with that. Evo theory is a good example of modifying the theory to accommodating evidence. But the observations come first before the modifications. We don't say "on planet XYZ we can imagine organisms that evolve by non-genetic processes" and then accept that into the theory.
ringo writes: A good definition of life should predict what we "might" find on other planets, not just what we have already found in our own back yard. My definition makes excellent predictions regarding life on other planets. There is no observational reasons to suggest any other form of life. We certainly can imagine all we want to. But that's not "science". It's Pseudo science. All panspermia hypotheses predict life on other planets as being similar to ours. Cellular based with amino acids and living according to my definition. What do you think they are looking for on Mars?...Cellular life or evidence therof.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Percy writes: What just isn't so? You said "You're attempting to create a definition where everything is either living or dead with no shades of gray in between." That just isn't so. I clearly identified entities in the grey area. You are just unhappy, because I don't call them alive. If they are not alive, then they are dead. You and RAZD want the grey area to be living. Then you must decide your definition of life and the differentiation between life and death. And both must make sense.
Percy writes: No. I said a lot more than that which you ignored. Read it again.
That's it? Just blindly declare it a faith-based premise and be done with it? Percy writes:
You've got to be kidding, Right? Chemicals don't have "organization, architecture or shape"? Don't you realize that every atom, molecule, and chemical combination has an architecture or shape associated with it? In particular, proteins must be folded to have the right shape to become either cellular tissue or enzymes. you can have misfolded proteins and they won't catalyze anything. They will have the exact same chemistry, but will not form the right tissue or catalyze the chemical reactions they are responsible for. A misfolded protein is usually a disease. Yes, Percy, organization, shape, and or architecture are very important in living things and it is not just chemicals doing their stuff.
Percy writes:
So you don't think heat and light affect chemical reactions? Would you like to research this a little before I embarrass you? And gravity also? Chemicals aren't subject to "electromagnetic radiation, and gravity. Yes, much of life is chemical, and all of life is physical, but life is more than just chemical processes. Edited by AlphaOmegakid, : No reason given.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Tany writes: I think you are misusing death here and several others have referred to non-living matter as "dead." Death is something that happens to living organisms when they stop functioning. Thanks Tany, I agree completely in a biological sense. So when does a virus die? No one is questioning that it is "alive" in the host cell (actually it is the infected cell that is alive). But outside the host, is it alive or dead? As a virion, is it alive, non-living, or dead? And how about self replicating molecules? When are they dead? etc etc.? Or are they ever alive? This is the reason that we need a good unequivocal definition of life.
Tany writes: Non-living material may not be the same thing as dead material. If it was never alive then it is just "non-living material." If it was once an organism that has died then it is dead. Dead material is the remains of a living organism that has gone through the process of death. Bingo! By George, me thinks he's got it! Maybe, I was too quick in the semantics by using the term "dead", but you can see that the term non-living is almost a synonym of "dead". I've been trying to semantically identify the so called grey area. "Non-living" is a perfectly good designation as far as my definition is concerned. The best term is abiotic! Abiotic component - Wikipedia So now we (you and I) have clarified the grey area. We have categories: (1) White=Living==>by some unequivocal definition of life(2) Grey=Abiotic=non-living (3) Black= Dead Within this model dead organisms are also abiotic material, but abiotic material that has never been alive is just abiotic material. I think this model works very well within Biology and especially well with my definition of life. The problem I was having was everyone else in this forum was referring to the grey area as "life" (the "grey area of life"). This makes no sense, because every abiotic thing would be on the pathway to life which is obviously false. The reality is that most abiotic things have no chance at life, many are dead, and some have some of the characteristics of living things. Thanks for your post! It was revealing. Now look at your last sentence, and consider a virus. If it is considered alive within the host cell. Then when the cell is destroyed and the virus is released again, then all life functions would be gone. It would be dead. Both abiotic and dead. This makes a lot of sense using this model. So a virus would not be in the grey area at all. It would be black.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Percy writes: No, I'm saying there's a region between alive (white in the image analogy) and not alive (black) that is neither living nor non-living (a shade of gray). No. I merely recognize that there's a gray area between living and non-living.
OK, then show me the semantics that clarify "alive" and "non-living" or the model of a grey area makes no legitimate scientific sense. There is no grey area unless white and black, which are unequivocal, are defined! So please make sense of this or drop the analogy.
My sentence wasn't a statement. Didn't you see the question mark? My question was rhetorical. Yes, I recognized that. However you were being quite selective in your quoting of my argument. I responded in kind. This post is much more civil!
This is just another bald declaration. We do have opposite ends of a continuum. A dog is obviously living. A block of lead is obviously non-living. Some things inhabit the region between living and non-living, like perhaps prions and viruses. See post 152
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
I didn't enjoy anything about this post. It is meaningless elephant hurling to the claims you made. You quoted my request....
RAZD writes: (1) It doesn't address the issue of viral life, which is increasingly being accepted as life forms as more is found out (self replication without host, metabolism and making of proteins used to encase it, etc) You have claimed this several times now. Admittedly, I am totally unaware of this. Evidence Please! Hopefully papers I can access on the web. Not journalistic articles I hope.+ You have claimed several times now that viruses can self replicate, metabolize and make proteins outside a host cell. I claim your bluffing or sadly misinformed on this. I have asked for supporting evidence to support this claim. You provided a bunch of non-relevant material. I will give you the benefit of a doubt. Please provide supporting evidence for your specific claim in yellow above, or withdraw it.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Percy writes: You're saying that, for example, water that was once but is no longer part of a living creature is "dead", but that water that has never been part of a living creature is "abiotic". I don't think that definition is going to work for anybody. No, I said nothing similar to that. But using the example of water, it is clear that water is essential to living things. Every abiogenetic hypothesis requires water!. So water by itself is in the non-living category (abiotic). It is not dead, because it has never been alive. But it is necessary and affects all life.
Why do you think a gray area between living and non-living implies that "every abiotic thing would be on the pathway to life." Water is an "abiotic thing," but most water in the universe is not likely on its way to becoming part of a living creature. I don't think that, nor do I imply that. I have provided an unequivocal definition of life. And recently, I have embraced the grey scale analogy to identify living, non-living, and dead. It works. All non-living things are in the grey area, living things are white, and dead things are black. The faithful evolutionary continuum from non-living to living through some form of chemical evolution is just speculative hypotheses at this moment. So I reject that there is a "pathway to life'. Water is abiotic, and of course necessary for life.
And then the virus enters another cell and is alive again? Really? Yes, really. That's exactly what we observe! All life comes from pre-existing life. This concept is perfectly consistent with cell theory and the law of biogenesis. We have a perfectly normal cell, and we have a viral infected cell. The virus is only alive in the sense that it is part of the original cell, and that now that it is within the cell it is disturbing and disorganizing the cell usually until it explodes the cell and releases the virions. Then those non-living virions hang around until they find another host. I think you would agree that poisons are abiotic and non-living. Yet they affect cells by disturbing their organization to such and extent that they destroy the cell. I think many doctors would agree that a virus can be interpreted as a very specific type of organic poison. In fact, they use the term "viral food poisoning" all the time.
Look at the list of examples of abiotic components from Wikipedia again. Why do you think a virus outside a host cell belongs on that list? That list is miniscule, but their definition is clear...
quote: I think a virus is a perfect example by observational evidence that it is a "non-living chemical and physical part of the environment that affects living organisms and the functioning of ecosystems." And at the same time there is no evidence that a virus is "on the pathway to life".
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
He He!
herebedragons writes:
That's OK, I about spit out my coffee when I read this! Your position just keeps getting stranger. Why would you put abiotic materials (which means "not biotic" or "not derived from living organisms") as the "grey" area between living and dead? That make NO sense at all. Because that's exactly what abiogenesis is all about!
quote: White = living - meets ALL the criteria for living creatures. I listed my version of this list in Message 132 quote: Black = Non-living - meets NONE of the criteria listed above Grey = Meets SOME of the criteria listed above, but not all of them. Ok let's examine your "strange" ideas. White=Living=meets all seven (7) criteria of life. OK, I will accept that. Now lets look at grey. Grey=some of the 7 criteria..anywhere from 1-6. Ok, so by those two definitions Grey is not alive which unfortunately makes it non-living. Now you and others have semantically called it "pre-life", "proto cells", "self-replicatiing molecules", and probably a whole lot of other things. But They are not alive by your own criteria. So for your model to be consistent and not self refuting, both the grey and the black are non-living. So by your criteria and model, anything less than living is non-living. Sorry to disappoint you but I had a good laugh.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
Percy writes: By "show me the semantics" are you asking for definitions of "living" and "non-living" of a specificity that we keep telling you doesn't exist? Dogs are living, a lead block is non-living. That's pretty unambiguous. The area between is ambiguous. Percy, you need to think this through logically. You just refuted yourself in two sentences. You just said that we cannot specifically define "living" and "non-living". Then you said specifically that a dog is "alive" and Lead is "non-living". That's why there at least equivocating characteristics of life that allow you to somewhat discern that a dog is "alive' and a block of lead is not. But that leaves us in just as bad a position scientifically, because we have sacrificed biological science to equivocating terms. Which logically is not good either.
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AlphaOmegakid Member (Idle past 2897 days) Posts: 564 From: The city of God Joined: |
tany writes: Ok, let's assume for a moment it is in the grey area, and the grey area is not a self refuted concept as already identified by the kid.(you are arguing like all the others.) Sorry, but I completely disagree with this. I consider the virus to be alive, but with a completely different life history from cellular organisms. I think it is a completely different life form that has evolved to take advantage of cellular organisms for metabolism and replication. In the abiogenesis history from non-life towards life, just how did virions evolve? Evidence please? Or hypotheses please? Before any cellular life existed, what chemical mechanism causes a virion to evolve? Or, are you saying that virions evolved after living cells evolved? Also, you just said you believe viruses are alive which contradicts your classification of "(1) White = Living, cellular organisms". Do you want to be contradictory, or do you want to correct this? Edited by AlphaOmegakid, : Added stuff
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