On the other hand, you have just 10e43 resources to scan through this space which means that evolution is physically impossible. |

There is one obvious flaw in your reasoning, even assuming the numbers are correctly calculated.

On the one hand, you are trying to count the total number of possible arrangements of molecules.

On the other hand, you are trying to calculate the total number of ways this arrangement could be changed. However, the number you actually present is supposed to be the number of possible mutations which could have happened.

Mutation is obviously not the only way in which the arrangement of these molecules can be changed. Environmental changes will also affect this, and the number of possible environmental effects is incalculably large. Your 10^43 should be many, many, many orders of magnitude larger.