I believe the answer to the question is yes. Beyond reasonable doubt doesn't mean 'for absolute certain' to me, otherwise virtually no-one would get convicted of a crime.
If science reaches a point where we have a very clear picture of how the universe and people work (including spiritual beliefs and spiritual experiences) without involving a God, we will have cracked it as far as I'm concerned. There would then be no reasonable grounds for believing in God.
Personally I look forward to the day. I don't believe we would end up without spirituality or a sense of meaning. The truth about the Universe is far richer than anything we have invented.