erikp writes:
Theories go from unprovenly false to provenly false. Scientific progress is the result of proving that what we know is wrong.
As soon as someone finally finds an observation that contradicts the theory, the theory will finally be proven to be false, because proof of falsehood only requires one observation that contradicts the theory.
This may hold true only about certain theories - multiverse, 10 dimensions, baby universes, quantum darwinism, eternal universe, infinite universe, etc. The structure of the world is elusive and crazy, but not so crazy as to be completely unknowable. Have you been on an airplane? How does that jive with your theory that nothing is fixed and certain? I imagine you would never board something that stays airborne on incorrect physical principles and theories.
The mere fact that the universe appears to have existed for 13.7 billion years is a good indication that its structure is solid and fixed and quite possibly knowable. That doesn't mean that all of our theories are correct, but that there most certainly is a path for us to follow. It is my belief that this path will yield us the answers we are looking for.