Phenomena like synaesthesia, schizophrenia and body-dismorphia with counter-intuitive problems like Monty Hall convince me further that I would not necessarily trust my experience over science - in contradiction to JavaMan in his Problem with Science II thread.
I was going to reply to your post even before I saw the reference to myself, because my own background (including the psychedelic drugs) is quite similar - although I'm not nearly so credulous
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My own opinions aren't that different from yours (at least your current ones), although I don't believe that nihilism or determinism are a necessary outcome of atheism and materialism.
The question of how much we should trust our own experience isn't really what the Problem with Science II thread is about, but I understand where you're coming from now. It might be worth you starting a thread about it if you can find a good hook.
P.S. Do drugs if you must, but not too much
'I can't even fit all my wife's clothes into a suitcase for travelling. So you want me to believe we're going to put all of the planets and stars and everything into a sandwich bag?' - q3psycho on the Big Bang