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Author Topic:   Excellent paper-peptide self assembly
Percy
Member
Posts: 22490
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.0


Message 3 of 50 (51967)
08-23-2003 11:36 AM
Reply to: Message 2 by sos
08-23-2003 12:29 AM


Re: Peptide self-assembly is one thing...
sos writes:
Chirality is still, to my knowledge, a BIG problem for abiogenesis as all modern living cells use exclusively L-form amino acids. Since one of the shortest protein chains known, insulin, is about 150 peptides in length, it would seem reasonable to look for a naturalistic process that can produce polypeptide chains of at least 150 all L-form amino acids... I don't think they have found it yet but there isn't much sense in discusssing the next level of problems unless a significant answer for naturally producing pure chirality is found first.
You describe chirality as a problem for abiogenesis, but your example has to do with protein size. I must be missing your point, because I don't see what one has to do with the other in relation to abiogenesis.
Is the faith of naturalists any better than the faith of creationists?
This question is better addressed in either the Is It Science? or Faith and Belief forum, but the short answer is that the positions of science are supported by evidence. When this isn't the case then it isn't science. Science believes that the physical laws in place today and for which we have much evidence were the same ones operating when life first formed. Creationism believes that a being for which there is no evidence using mechanisms for which there is no evidence created the first life.
You can get free access to Science Online, but it doesn't provide access to most content, including the mentioned article.
--Percy

This message is a reply to:
 Message 2 by sos, posted 08-23-2003 12:29 AM sos has not replied

Replies to this message:
 Message 4 by Rei, posted 09-18-2003 8:32 PM Percy has not replied
 Message 6 by DNAunion, posted 11-01-2003 12:11 AM Percy has replied

  
Percy
Member
Posts: 22490
From: New Hampshire
Joined: 12-23-2000
Member Rating: 5.0


Message 12 of 50 (63916)
11-02-2003 9:01 AM
Reply to: Message 6 by DNAunion
11-01-2003 12:11 AM


Re: Peptide self-assembly is one thing...
DNAunion writes:
Probability. If there is some mechanism directing the selection of amino acid enantiomers - ensuring that the L form is always picked - then length is irrelevant. But when the process occurs by undirected, non-biological processes, an easily made assumption is that both chiral forms - being present in equal quantities and being chemically equivalent - would be incorporated at random in a growing chain.
And is the assumption that left and right handed amino-acids bond readily to one another valid?
Whether they do or not, I still can't see how this is a "BIG problem for abiogenesis", which is how Sos described it. My own perspective is that the actual "BIG problem for abiogenesis" is that so little is known, dwarfing problems like chirality by comparison.
--Percy

This message is a reply to:
 Message 6 by DNAunion, posted 11-01-2003 12:11 AM DNAunion has not replied

  
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