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Author Topic:   Abiogenisis by the Numbers
happy_atheist
Member (Idle past 4934 days)
Posts: 326
Joined: 08-21-2004


Message 46 of 206 (159114)
11-13-2004 3:58 PM
Reply to: Message 38 by RisenLord
11-12-2004 10:49 PM


RisenLord writes:
And no preexisting bonds are broken in the process, I assume........I see. I didn't know that. Thanks for the info. What are the implications of these chemical reactions for or against either of our arguments?
Surely amino acids dissolving in water is exactly what makes it possible to make long chains of them. If they were insoluble how exactly would they join to other amino acids? If hydrogen atoms weren't removed from the amino acids, how could a different amino acid take it's place?

This message is a reply to:
 Message 38 by RisenLord, posted 11-12-2004 10:49 PM RisenLord has replied

Replies to this message:
 Message 48 by RisenLord, posted 11-13-2004 5:03 PM happy_atheist has replied

  
RisenLord 
Inactive Member


Message 47 of 206 (159122)
11-13-2004 5:00 PM
Reply to: Message 40 by crashfrog
11-13-2004 12:01 AM


I totally don't understand what you mean in this sentence. "Genisis"? You mean "genesis"? Or "Genus"?
No, I meant "Crashfrog is a pompous ass for pointing out spelling errors and thinking it gives him an edge in a debate".
No, actually, there were a number of bizarre observations that relativity immediatly explained
Are you telling me there was one SHREAD of proof for special relativity prior to the theory being proposed?
When we come to conclusions about abiogenesis, its because of the evidence of observation and experiment, not from mathematics.
Damn straight about the mathematics part........as for evidence, how much evidence for abiogenesis falls outside of the "here's some naturally occuring goop" category?
There are a number of competeing theories besides String Theory that purport to account for the initial conditions of the Big Bang.
No......no, there aren't. Every multi or oscillating universe theory is dependant on string theory to explain the amount of variablity between universes.
And you appear to have misunderstood my point. I didn't say that string theory was wrong. In fact, that's why it currently isn't really a theory at all; there's no way to know if it's wrong.
You're right........it's an hypothesis.........just like abiogenesis.
We have a truckload of competiting theories that explain why there was a Big Bang; the problem isn't that none of them are right, it's that we don't know which ones are wrong.
String theory has nothing to do with what caused the Big Bang.
Without a very, very clear idea of what you mean by "living thing"
And why would scientists have an idea of that? Isn't like we've been studying living things for millenia.........
First life would've had to have been a lipid cell with genetic material inside sufficient to metabolize and reproduce.......both of which, if I'm not mistaken, require proteins. We have no reason to think that any form of life that's simpler can exist.
To me, "life" merely describes a certain kind of chemistry. A single protein molecule could easily manage the chemical reactions necessary to be considered, if not alive, then a precursor to life.
And the odds against that single protein forming are a google to one........
Where did those complex molecules come from? Through non-living, but complex, chemistry building on simpler molecules.
True. And it's mathematically IMPOSSIBLE for such things to self-assemble, barring future discoveries which we have no reason to believe we'll make.
As a matter of fact, they almost immediately started performing complex chemical interactions in budded-off vescicles; interactions that could not occur in the surrounding matrix, interactions that led to an expansion and bifurcation of these bilayer membranes. So, yes, they did start replicating and metabolizing.
Funny how I don't see the words "replicate" or "metabolize" anywhere in your description of what the lipid bilayer was doing........only in the summary.
Of course, the biggest difference between lipid bilayer membranes and soap bubbles is that bilayer membranes are self-assembling, like the organelles of the cells of living things. Soap bubbles are not.
Really? Because I don't recall tweaking molecules to form a bubble the last time I washed my hands........it just kinda happened.

This message is a reply to:
 Message 40 by crashfrog, posted 11-13-2004 12:01 AM crashfrog has replied

Replies to this message:
 Message 49 by Coragyps, posted 11-13-2004 5:19 PM RisenLord has replied
 Message 55 by crashfrog, posted 11-13-2004 5:32 PM RisenLord has replied

  
RisenLord 
Inactive Member


Message 48 of 206 (159124)
11-13-2004 5:03 PM
Reply to: Message 46 by happy_atheist
11-13-2004 3:58 PM


Surely amino acids dissolving in water is exactly what makes it possible to make long chains of them. If they were insoluble how exactly would they join to other amino acids? If hydrogen atoms weren't removed from the amino acids, how could a different amino acid take it's place?
I dunno, that's why I asked.......I don't understand why disolving would help amino acids form into proteins.

This message is a reply to:
 Message 46 by happy_atheist, posted 11-13-2004 3:58 PM happy_atheist has replied

Replies to this message:
 Message 52 by Loudmouth, posted 11-13-2004 5:24 PM RisenLord has replied
 Message 57 by happy_atheist, posted 11-13-2004 7:09 PM RisenLord has not replied

  
Coragyps
Member (Idle past 755 days)
Posts: 5553
From: Snyder, Texas, USA
Joined: 11-12-2002


Message 49 of 206 (159128)
11-13-2004 5:19 PM
Reply to: Message 47 by RisenLord
11-13-2004 5:00 PM


And the odds against that single protein forming are a google to one........
Show your work.

This message is a reply to:
 Message 47 by RisenLord, posted 11-13-2004 5:00 PM RisenLord has replied

Replies to this message:
 Message 51 by RisenLord, posted 11-13-2004 5:21 PM Coragyps has replied

  
RisenLord 
Inactive Member


Message 50 of 206 (159129)
11-13-2004 5:20 PM
Reply to: Message 41 by pink sasquatch
11-13-2004 2:40 AM


Not when you are talking about probabilities. You need some knowledge about conditions and complexity to start talking probabilities.
This is true. And ID advocates assume favorable conditions for abiogenesis when making their equations........and they also assume a level of complexity (a single protein) which is much less complex than first life most likely had to have been.
However, the ID camp often looks at the composition of a single living cell today and tries to come up with a simple probability of it forming randomly. Since the "first life" was likely not a fully intact "modern" cell, probabilities calculated based on that assumption are pointless strawmen.
I have NEVER seen an ID proponent do this.
I don't agree with that at all, mainly because I don't think the first life needed any protein at all.
The interesting thing about RNA is that it can act as a genetic template, and it can have catalytic activity like protein enzymes (including acting as a polymerase to replicate RNA). Since it is an imperfectly replicating template, mutation and selection can act upon it increase its stability and activity (survival).
RNA strands also form from strictly chemical processes.
According to Behe, nucleic acids are much more complex than amino acids and, therefore, getting RNA to self-assemble would be a "walk in the park" compared to getting a protein to do so.
So, I reiterate.........first life was certainly no less complex than a single protein molecule.
Because of these characteristics, short RNA replicators seem the most likely "first life". Later association with lipid micelles would have created the first cell.
Sounds rather vague......what kind of "later association" are you referring to?

This message is a reply to:
 Message 41 by pink sasquatch, posted 11-13-2004 2:40 AM pink sasquatch has replied

Replies to this message:
 Message 56 by Coragyps, posted 11-13-2004 5:33 PM RisenLord has replied
 Message 58 by pink sasquatch, posted 11-13-2004 7:12 PM RisenLord has replied

  
RisenLord 
Inactive Member


Message 51 of 206 (159131)
11-13-2004 5:21 PM
Reply to: Message 49 by Coragyps
11-13-2004 5:19 PM


Coragyps, you'll have to shell out some money on some Dembski for that one......

This message is a reply to:
 Message 49 by Coragyps, posted 11-13-2004 5:19 PM Coragyps has replied

Replies to this message:
 Message 54 by Coragyps, posted 11-13-2004 5:30 PM RisenLord has replied

  
Loudmouth
Inactive Member


Message 52 of 206 (159132)
11-13-2004 5:24 PM
Reply to: Message 48 by RisenLord
11-13-2004 5:03 PM


quote:
I dunno, that's why I asked.......I don't understand why disolving would help amino acids form into proteins.
If you have ever taken a chemistry class, you may remember that 99% of the reactions carried out in lab occur in water. Water is an ideal liquid for chemical reactions to occur. For amino acids, when they are dissolved in water it becomes possible for these amino acids to react with each other and create a polymer. This is because amino acids have a carboxy terminus (the negative end) and a amino terminus (the positive end). When certain conditions are right, the negative and positive ends connect like legos, creating a protein. Most of these conditions require the amino acids to be dissolved in water in order for them to have a medium to react in.

This message is a reply to:
 Message 48 by RisenLord, posted 11-13-2004 5:03 PM RisenLord has replied

Replies to this message:
 Message 59 by RisenLord, posted 11-13-2004 7:24 PM Loudmouth has not replied

  
Loudmouth
Inactive Member


Message 53 of 206 (159133)
11-13-2004 5:25 PM


Risenlord,
Could you please supply the first replicator that Dembski based his probabilities on? Without this knowledge we can't critique his choice of the first replicator nor the calculations he used. Also, without this knowledge, your assertions mean nothing.

Replies to this message:
 Message 62 by RisenLord, posted 11-13-2004 7:38 PM Loudmouth has not replied

  
Coragyps
Member (Idle past 755 days)
Posts: 5553
From: Snyder, Texas, USA
Joined: 11-12-2002


Message 54 of 206 (159134)
11-13-2004 5:30 PM
Reply to: Message 51 by RisenLord
11-13-2004 5:21 PM


Coragyps, you'll have to shell out some money on some Dembski for that one......
You seem familiar enough with his work, and I'm a very cheap individual. Give us a summary of how he got a google to one odds, and we'll all be grateful.

This message is a reply to:
 Message 51 by RisenLord, posted 11-13-2004 5:21 PM RisenLord has replied

Replies to this message:
 Message 63 by RisenLord, posted 11-13-2004 7:41 PM Coragyps has replied

  
crashfrog
Member (Idle past 1487 days)
Posts: 19762
From: Silver Spring, MD
Joined: 03-20-2003


Message 55 of 206 (159135)
11-13-2004 5:32 PM
Reply to: Message 47 by RisenLord
11-13-2004 5:00 PM


No, I meant "Crashfrog is a pompous ass for pointing out spelling errors and thinking it gives him an edge in a debate".
I wasn't trying to be pompous, and I never criticize for spelling, as a rule.
I simply didn't understand what you meant in that sentence, and I still don't. I'm still not sure if you meant "genesis" or "genus", because either way, your sentence still doesn't make any sense to me. So explain what you meant, already. Calling me names doesn't increase my understanding, or make you look any better as a communicator.
Are you telling me there was one SHREAD of proof for special relativity prior to the theory being proposed?
Yeah. Mercury wasn't where the Newtonian models said it would be. Relativity explained why, though that wasn't what led Einstein to come up with the theory. But almost immediately that was how people knew he was on to something.
as for evidence, how much evidence for abiogenesis falls outside of the "here's some naturally occuring goop" category?
Well, shit, dude, what would you expect evidence for abiogenesis to look like? "Using naturally occuring processes under situations mimicing ancient Earth, we were able to stimulate the formation of this substance or structure, which is suspected of being a chemical precursor of life."
Absolutely none of what we've described, so far, constitutes "goop". Your use of that word further betrays the chasm of ignorance that separates you from substantive debate on this issue.
No......no, there aren't.
Again, simply wrong. Had you made a cursory effort to inform yourself, you would have discovered that loop quantum gravity, noncommutative geometry, and Penrose's "Twistor theory" are all competing, non-string-based cosmological models.
You're right........it's an hypothesis.........just like abiogenesis.
I'm not sure why you feel that's any sort of criticism. Studying the chemical precursors to life, seeing as how they no longer exist, is quite difficult. That we have any results at all, currently, is a considerable testament to the ingenuity of biochemists.
String theory has nothing to do with what caused the Big Bang.
As a theory of quantum gravity, in fact, it directly addresses the cause of the Big Bang.
And why would scientists have an idea of that? Isn't like we've been studying living things for millenia.........
Because the universe doesn't tend to be black and white. Our classifications of things don't really reflect inherent natures in reality; they're just convinient boxes for us to put things into. The universe is under no obligation to operate in a way that lends itself towards easy classification.
The other problem that makes it difficult is that living things are made from the exact same kinds of things as non-living ones.
First life would've had to have been a lipid cell with genetic material inside sufficient to metabolize and reproduce.....
Why?
We have no reason to think that any form of life that's simpler can exist.
Circular logic. If a simpler precursor to that organism did exist, which, in all likelyhood it did, you wouldn't consider it alive.
The question is not "what is the first living thing?" The question is, what is the ultimate chemical precursor to all living things?
And the odds against that single protein forming are a google to one........
Well, the odds that you would be you, and not someone else, are one out of the total number of sperm released by your father.
But that's not evidence that you don't exist, now is it?
And it's mathematically IMPOSSIBLE for such things to self-assemble
Oh? Impossible, is it?
Prove it. Show me the math. Self-assembly occurs constantly in nature. It's surprisingly frequent for something you claim to be impossible.
Funny how I don't see the words "replicate" or "metabolize" anywhere in your description of what the lipid bilayer was doing........
This doesn't even make any sense. My description makes it abundantly clear that those processes were occuring. Do you know what those words even mean? Because it looks like you don't.
Because I don't recall tweaking molecules to form a bubble the last time I washed my hands........it just kinda happened.
Look, let me make it absolutely clear, because you don't seem to get it. Lipid bilayers aren't soap bubbles. Only someone completely ignorant of the simplest aspects of biochemistry would be confused about the two.

This message is a reply to:
 Message 47 by RisenLord, posted 11-13-2004 5:00 PM RisenLord has replied

Replies to this message:
 Message 73 by RisenLord, posted 11-14-2004 3:35 PM crashfrog has replied

  
Coragyps
Member (Idle past 755 days)
Posts: 5553
From: Snyder, Texas, USA
Joined: 11-12-2002


Message 56 of 206 (159136)
11-13-2004 5:33 PM
Reply to: Message 50 by RisenLord
11-13-2004 5:20 PM


According to Behe, nucleic acids are much more complex than amino acids and, therefore, getting RNA to self-assemble would be a "walk in the park" compared to getting a protein to do so.
Clarify what you/Behe are saying here, please. RNA is much easier to assemble than a protein because its building blocks are more complex??

This message is a reply to:
 Message 50 by RisenLord, posted 11-13-2004 5:20 PM RisenLord has replied

Replies to this message:
 Message 61 by RisenLord, posted 11-13-2004 7:36 PM Coragyps has not replied

  
happy_atheist
Member (Idle past 4934 days)
Posts: 326
Joined: 08-21-2004


Message 57 of 206 (159154)
11-13-2004 7:09 PM
Reply to: Message 48 by RisenLord
11-13-2004 5:03 PM


[qs ]I dunno, that's why I asked.......I don't understand why disolving would help amino acids form into proteins.[/qs]
I think Loudmouth beat me to it (right down to the lego brick analogy, which I was going to use myself). It strikes me as very odd that your sources would say that amino acids dissolving is a bad thing.

This message is a reply to:
 Message 48 by RisenLord, posted 11-13-2004 5:03 PM RisenLord has not replied

  
pink sasquatch
Member (Idle past 6043 days)
Posts: 1567
Joined: 06-10-2004


Message 58 of 206 (159157)
11-13-2004 7:12 PM
Reply to: Message 50 by RisenLord
11-13-2004 5:20 PM


According to Behe, nucleic acids are much more complex than amino acids and, therefore, getting RNA to self-assemble would be a "walk in the park" compared to getting a protein to do so. So, I reiterate.........first life was certainly no less complex than a single protein molecule.
Another ambiguous claim with no numbers to back it up...
The classic ID equation makes some assumptions that are not at all "favorable" as you suggest. To start, why does Behe insist on using protein for his calculations rather than RNA? It's quite simple, because proteins needs to have more units, and have more options for units, than RNA.
The ID "favorable" conditions usually claim that a protein needs to be at least 300 amino acids long to be functional, and there are at least 20 amino acids to choose from. They assume that only one specific sequence will produce anything useful (which is false), so the odds become:
1 in 20^300 ; or
1 in 20000000000000000000000000000000000000000000000000000
00000000000000000000000000000000000000000000000000000000000
00000000000000000000000000000000000000000000000000000000000
00000000000000000000000000000000000000000000000000000000000
00000000000000000000000000000000000000000000000000000000000
000000000000000000000000000000000000000000
or as you might say, "impossible".
However, let's examine an RNA-based RNA polymerase replicator that has been discovered in actual laboratory experiments:
26 units long, with 4 possible units, assuming that only one sequence is useful:
1 in 4^26; or
1 in 4500000000000000
Suddenly the odds are a lot less "impossible", and I assumed that only a single 26 bp sequence would have activity; we know that many other sequences have activity, so the odds are much less than stated above.
In addition, some experiments suggest that the minimal RNA length with catalytic activity is 8 bp:
1 in 4^8; or
1 in 65536
Again, these odds include the assumption that only one 8 bp RNA has catalytic activity.
Hopefully you see that the IDers have NOT used simple, "favorable" conditions to determine their probabilities.

This message is a reply to:
 Message 50 by RisenLord, posted 11-13-2004 5:20 PM RisenLord has replied

Replies to this message:
 Message 60 by RisenLord, posted 11-13-2004 7:33 PM pink sasquatch has replied

  
RisenLord 
Inactive Member


Message 59 of 206 (159163)
11-13-2004 7:24 PM
Reply to: Message 52 by Loudmouth
11-13-2004 5:24 PM


Loudmouth, thanks for the info.

This message is a reply to:
 Message 52 by Loudmouth, posted 11-13-2004 5:24 PM Loudmouth has not replied

  
RisenLord 
Inactive Member


Message 60 of 206 (159169)
11-13-2004 7:33 PM
Reply to: Message 58 by pink sasquatch
11-13-2004 7:12 PM


Another ambiguous claim with no numbers to back it up...
The classic ID equation makes some assumptions that are not at all "favorable" as you suggest.
Speaking of ambiguous claims with nothing to back them up....
To start, why does Behe insist on using protein for his calculations rather than RNA?
For starters, Behe gives no calculations at all......the numbers I've mentioned are from other scientists. Behe simply asserts that RNA is much less likely to self-assemble than proteins. Also, the RNA world theory is FAR from universally accepted and has many critics in the abiogenesis camp.....most theories involving abiogenesis have to do with proteins.
It's quite simple, because proteins needs to have more units, and have more options for units, than RNA.
And nucleic acids are themselves very complex apparently.......much more complex than amino acids.......and have tendancies which would make it very difficult for them to self-assemble.
The ID "favorable" conditions usually claim that a protein needs to be at least 300 amino acids long to be functional
I've never heard such a claim.
However, let's examine an RNA-based RNA polymerase replicator that has been discovered in actual laboratory experiments:
"Discovered"? You mean "intelligently designed" in labroatory experiments, don't you? And that bit of replicating RNA is NOT a life form.......
In addition, some experiments suggest that the minimal RNA length with catalytic activity is 8 bp:
1 in 4^8; or
1 in 65536
Oh, yeah, one in 65536......that's a sure thing......

This message is a reply to:
 Message 58 by pink sasquatch, posted 11-13-2004 7:12 PM pink sasquatch has replied

Replies to this message:
 Message 65 by pink sasquatch, posted 11-13-2004 8:00 PM RisenLord has replied

  
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