The local variation in a population is reversible (micro-evolution) but is macro-evolution reversible? Obviously not exactly but if conditions changed then would evolution back-track?
Evolution doesn't have a direction so surely it is possible for it to go backwards?
Didn't you just answer your question? If evolution doesn't have a direction, then going backwards is a contradiction in terms, as "backwards" is indicative of being directional.
If evolution simply means, "change," then there is no forward or backwards, just different.
If you are asking if humans can somehow devolve back in to single-celled organelles, I would think not.