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Author Topic:   Question about evolution, genetic bottlenecks, and inbreeding
harry
Member (Idle past 5495 days)
Posts: 59
Joined: 03-15-2009


Message 46 of 123 (503127)
03-16-2009 9:26 AM
Reply to: Message 45 by Dr Adequate
03-16-2009 9:23 AM


Re: Nope
When we discuess scientific definitions things do not always mean what they say though do they. IF they did, we wouldnt need defintions.
I have found these definitions, and you are saying they do not matter. Ofcourse they matter, the are written by emininent biolgists for a reason.
You can not just brush aside these defintions, there must be a way to reconcile/disprove why an individual is not guarenteed to be an MRCA at some point down the line.
How do I upload pictures?

This message is a reply to:
 Message 45 by Dr Adequate, posted 03-16-2009 9:23 AM Dr Adequate has replied

Replies to this message:
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Dr Adequate
Member (Idle past 312 days)
Posts: 16113
Joined: 07-20-2006


Message 47 of 123 (503129)
03-16-2009 9:33 AM
Reply to: Message 46 by harry
03-16-2009 9:26 AM


Re: Nope
When we discuess scientific definitions things do not always mean what they say though do they. IF they did, we wouldnt need defintions.
The definitions of "most" and "recent" aren't different in biology.
I have found these definitions, and you are saying they do not matter. Ofcourse they matter, the are written by emininent biolgists for a reason.
Quote these eminent biologists.
You can not just brush aside these defintions, there must be a way to reconcile/disprove why an individual is not guarenteed to be an MRCA at some point down the line.
I didn't follow that.
How do I upload pictures?
You don't. You put img tags around the internet address of the picture you want to display. If it doesn't have an internet address, upload it to an image hosting site such as ImageShack.
Edited by Dr Adequate, : No reason given.

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Dr Adequate
Member (Idle past 312 days)
Posts: 16113
Joined: 07-20-2006


Message 48 of 123 (503130)
03-16-2009 9:40 AM
Reply to: Message 45 by Dr Adequate
03-16-2009 9:23 AM


Re: Nope
Further to my previous remarks, consider the possibility that individuals C and D lived, or reproduced, later than A, B, E, F, G and H (which is perfectly possible as generations don't go regularly like the ticking of a clock).
Then they would be more recent than Adam or Eve. Adam would still be the MRCA in the male line, but not an MRCA. Eve would still be the MRCA in the female line, but not an MRCA.

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PaulK
Member
Posts: 17827
Joined: 01-10-2003
Member Rating: 2.3


Message 49 of 123 (503131)
03-16-2009 9:41 AM
Reply to: Message 44 by harry
03-16-2009 9:16 AM


Re: Would you Adam and Eve it?
quote:
Ok so this is my point. If we reach this point, where we have narrowed down the most recent common ancestor down to two people in our quest to find one (if my definition is correct). Plenty of others could have contribured to the gene pool, but these are the direct ancestors.
No. You have found TWO common ancestors. The most recent common ancestor *might* be the most recent of these two or (more likely) is another more recent individual.
That is because (ignoring complications) the Y-chromosome lineage ONLY considers male-to-male (father-to-son) descent. The mitochondrial lineage ONLY considers the female line (mother-to-daughter). To find the MOST recent common ancestor we must relax those restrictions to include all lines of descent.
quote:
(Althought I am note sure. If the common ancestor of everyone today, had kids with only one woman as you suggest, they would both the M-Eve and Y-Adam, as they are both the most recent examples of where everyone got their chromosomes.
This is not true. Even if the most recent common ancestors were a strictly monogamous couple, with no other partners, it would probably be false. For the man to be a Y-chromosome Adam everybody must be descended from one of his sons. For a woman to be the mitochondrial Eve everyone must be descended from one of her daughters. But to be the most common ancestors all that is necessary is that everyone must have (at least) one of their children - son OR daughter - as an ancestor.

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Dr Jack
Member
Posts: 3514
From: Immigrant in the land of Deutsch
Joined: 07-14-2003
Member Rating: 8.3


Message 50 of 123 (503133)
03-16-2009 9:52 AM
Reply to: Message 44 by harry
03-16-2009 9:16 AM


Re: Would you Adam and Eve it?
(Althought I am note sure. If the common ancestor of everyone today, had kids with only one woman as you suggest, they would both the M-Eve and Y-Adam, as they are both the most recent examples of where everyone got their chromosomes.
The could be our MCRAs without either their Y-chromosome line or their mitochondria being represented in the modern population if, just for example, the had only a single son, and then that son had only daughters (this argument applies equally to a single MCRA).

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Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 51 of 123 (503135)
03-16-2009 10:09 AM
Reply to: Message 42 by harry
03-16-2009 8:33 AM


Re: Would you Adam and Eve it?
No one has dealt with the fact that all the definitions I have found refer to the MRCA as an individual, not a group. If you can address this the conversation is complete. IF I am reading the definition wrong, what do they mean by individual
In the scenario described, who is the most recent common ancestor of S and T, according to your understanding?

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NosyNed
Member
Posts: 9004
From: Canada
Joined: 04-04-2003


Message 52 of 123 (503136)
03-16-2009 10:16 AM
Reply to: Message 35 by harry
03-16-2009 7:17 AM


The Y Adam
You are right that A is the Y Adam to the last generation on the chart (I hadn't noticed that ).
But all the first generation individuals (A -H) have descendents in the last generation so they are all ancestors to "today's" generation and they are all equally "recent". The whole population of A-H is exactly 3 generations back from S-Z. None of A-H is more recent than any others.

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harry
Member (Idle past 5495 days)
Posts: 59
Joined: 03-15-2009


Message 53 of 123 (503149)
03-16-2009 12:37 PM
Reply to: Message 49 by PaulK
03-16-2009 9:41 AM


Re: Would you Adam and Eve it?
quote:
No. You have found TWO common ancestors. The most recent common ancestor *might* be the most recent of these two or (more likely) is another more recent individual.
Yeah sorry I worded that wrong. I will get back later tonight with a diagram to help explain what I mean

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harry
Member (Idle past 5495 days)
Posts: 59
Joined: 03-15-2009


Message 54 of 123 (503153)
03-16-2009 1:28 PM
Reply to: Message 53 by harry
03-16-2009 12:37 PM


Re: Would you Adam and Eve it?
Okie kokie
First
quote:
Quote these eminent biologists:
'Concestor 0 is the most recent ancestor that unites the geograpahically divided population' Dawkins, page 45 ancestors tale.
See graph on page 49 of the book to see how ONE PERSON is the most recent common ancestor of all mankind.
(I will deal with this again later)
You can go on natural journals if you have access and see references.
quote:
However, if we consider not just our all-female and
all-male lines, but our ancestors along all parental lines,
it turns out that everyone on earth may share a common
ancestor who is remarkably recent....that the
common ancestor of everyone alive today very likely lived
between 2,000 and 5,000 years ago.
Douglas Rhode, On the Common Ancestors of All Living Humans
If you guys are so sure of yourself, you should be doing research yourself.
Now looky here
I have drawn this in response to
quote:
No. You have found TWO common ancestors. The most recent common ancestor *might* be the most recent of these two or (more likely) is another more recent individual.
If we assume the top two people on the chart are Y-adam and M-Eve, we have our two common ancestors. Now their son (their can be any period of time in between the Adam and Eve and the son I have drawn, it does not matter. However, now, say we are descended from people living in Asia. Who is the whole human races Y adam? They guy at the top, assuming his other son survived and passed on his genes and did not interbreed with the population on the chart.
However who is the MOST Recent common ancestor of all the asian and african populations? Adam's skip however many generations son!
Now all you need to do, is extropolate this to where one son split off to be a chimpanzee, and another split off to become humans.
If anyone here can draw me a tree disproving that there must have at some point been someone who is the ancestor of all humans. I'll shut up. But I am 99% sure that a Most recent common ancestor is an individual
Edited by harry, : No reason given.
Edited by harry, : No reason given.
Edited by Adminnemooseus, : change image to thumnail.

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Replies to this message:
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 Message 59 by PaulK, posted 03-16-2009 3:17 PM harry has replied
 Message 66 by Dr Adequate, posted 03-16-2009 5:27 PM harry has replied

  
bluescat48
Member (Idle past 4217 days)
Posts: 2347
From: United States
Joined: 10-06-2007


Message 55 of 123 (503155)
03-16-2009 2:16 PM
Reply to: Message 54 by harry
03-16-2009 1:28 PM


Re: Would you Adam and Eve it?
Now all you need to do, is extropolate this to where one son split off to be a chimpanzee, and another split off to become humans.
If anyone here can draw me a tree disproving that there must have at some point been someone who is the ancestor of all humans. I'll shut up. But I am 99% sure that a Most recent common ancestor is an individual
One point, the MCRA of both humans & chimps would also be the MRCA to any other chimpoid species (no fossils have been found as of yet) and to the hominid genera, Sahelanthropus, Orrorin, Ardipithrcus, Australopithicus, Parantropus, Kenyanthropus & Homo.
source: Evolution A Scientific American Reader pg 285 b/Ian Tattersall

There is no better love between 2 people than mutual respect for each other WT Young, 2002
Who gave anyone the authority to call me an authority on anything. WT Young, 1969
Since Evolution is only ~90% correct it should be thrown out and replaced by Creation which has even a lower % of correctness. W T Young, 2008

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harry
Member (Idle past 5495 days)
Posts: 59
Joined: 03-15-2009


Message 56 of 123 (503157)
03-16-2009 2:19 PM
Reply to: Message 55 by bluescat48
03-16-2009 2:16 PM


Re: Would you Adam and Eve it?
quote:
One point, the MCRA of both humans & chimps would also be the MRCA to any other chimpoid species (no fossils have been found as of yet) and to the hominid genera, Sahelanthropus, Orrorin, Ardipithrcus, Australopithicus, Parantropus, Kenyanthropus & Homo.
Agreed

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Taq
Member
Posts: 10080
Joined: 03-06-2009
Member Rating: 5.1


Message 57 of 123 (503158)
03-16-2009 3:04 PM
Reply to: Message 44 by harry
03-16-2009 9:16 AM


Re: Would you Adam and Eve it?
Ok so this is my point. If we reach this point, where we have narrowed down the most recent common ancestor down to two people in our quest to find one (if my definition is correct). Plenty of others could have contribured to the gene pool, but these are the direct ancestors.
The direct ancestors of what? You need context. Mit-Eve is the MRCA for all of our mitochondria. Y-Adam is the MRCA of our Y-chromosome. In fact, every single allele has it's own MRCA. As one example, there are hundreds of DRB1 alleles in the human population. It has been suggested that the MRCA for the DRB1 allele existed 60 million years ago.
**************************************************
Science. 1995 Dec 22;270(5244):1930-6.
Comment in:
Science. 1996 May 31;272(5266):1363-4.
Science. 1996 Nov 29;274(5292):1552-4.
The myth of Eve: molecular biology and human origins.
Ayala FJ.
University of California, Irvine, USA.
It has been proposed that modern humans descended from a single woman, the "mitochondrial Eve" who lived in Africa 100,000 to 200,000 years ago. The human immune system DRB1 genes are extremely polymorphic, with gene lineages that coalesce into an ancestor who lived around 60 million years ago, a time before the divergence of the apes from the Old World monkeys. The theory of gene coalescence suggests that, throughout the last 60 million years, human ancestral populations had an effective size of 100,000 individuals or greater. Molecular evolution data favor the African origin of modern humans, but the weight of the evidence is against a population bottleneck before their emergence. The mitochondrial Eve hypothesis emanates from a confusion between gene genealogies and individual genealogies.
**************************************************
(NOTE: other scientists have suggested that the 60 million date is way off)
What you need to keep in mind is that mitochondria and the Y-chromosome are passed on as units. The Y-chromosome does not recombine with other chromosomes during meiosis like the autosomal chromosomes do. Therefore, mitochondria and the Y-chromosome can be treated like really big alleles.
As for the common ancestor of two species, this is a different concept. In this case the context is shared DNA. The common ancestor of two species was a population that contained, at minimum, the DNA shared by the two species. Of course, no single organism in a population can carry the variability of a whole population.
Edited by Taq, : No reason given.

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harry
Member (Idle past 5495 days)
Posts: 59
Joined: 03-15-2009


Message 58 of 123 (503159)
03-16-2009 3:09 PM
Reply to: Message 57 by Taq
03-16-2009 3:04 PM


Re: Would you Adam and Eve it?
Thats all well and good, but I am talking about the ancestors of individual creatures, not of individual genes.
quote:
Ok so this is my point. If we reach this point, where we have narrowed down the most recent common ancestor down to two people in our quest to find one (if my definition is correct). Plenty of others could have contribured to the gene pool, but these are the direct ancestors.
Disregard it, I phrased it badly and it was wrong anyway. I think my most recent post explains my position well enough.
I am now saying a MRCA can not be a group of individuals and i am inviting someone to disprove me.

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PaulK
Member
Posts: 17827
Joined: 01-10-2003
Member Rating: 2.3


Message 59 of 123 (503160)
03-16-2009 3:17 PM
Reply to: Message 54 by harry
03-16-2009 1:28 PM


Re: Would you Adam and Eve it?
quote:
Now all you need to do, is extropolate this to where one son split off to be a chimpanzee, and another split off to become humans.
Presumably you mean to take the most recent male-line common ancestor of both chimps and humans. In that case the male lines of common descent for chimps and humans would lead back to different sons of this individual.
But what is the point ? Once we remove the restriction of looking only at a pure male line we may find that both of the sons are common ancestors of humans and chimpanzees - and we would almost certainly
find that there were other common ancestors amongst the population of that time. The existence of common ancestors does not in itself apply bottlenecks.

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harry
Member (Idle past 5495 days)
Posts: 59
Joined: 03-15-2009


Message 60 of 123 (503166)
03-16-2009 3:57 PM
Reply to: Message 59 by PaulK
03-16-2009 3:17 PM


Re: Would you Adam and Eve it?
quote:
The existence of common ancestors does not in itself apply bottlenecks.
Yeah I got that, staga explained it. However I am uneasy with people saying a Most Recent Common ancestor can be a group of people.
Can we confirm there must a single most recent individual common ancestor to all humans? Or do we disagree on that to?

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