NJ, I suggest you maintain your focus and think before you post. You seem to have trouble following the discussion.
The problem is, I can't think of one instance in where cancer, Down Syndrome, or Cystic Fibrosis benefitted anyone in any way.
Since we already have discussed the idea that some mutations are detrimental and the NS can remove some of them from the gene pool how does it further the discussion to point out that some changes are not beneficial in regards to reproductive success?
I think that evolutionists silently agree that they'd love nothing more than an actual fossil that undeniably points to one species forming into an entirely new taxonomical niche
This is both jumping ahead in the discussion and something that is obviously silly in light of what the evolutionary explanation actually says.
You have been given an opportunity to learn something. Those kinds of statements demonstrate that you need to take advantage of it.