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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
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Author | Topic: Some mutations sound too good to be true | |||||||||||||||||||||||
PaulK Member Posts: 17825 Joined: Member Rating: 2.2 |
No, you are wrong to say that the cheetah's ahven't recovered their genetic variability. Partly thanks ot more recent - but less severe - bottlenecks the cheetahs are still suffering the effects but their variability has recovered to some extent.
Postulating greater genetic variability is not much help. Even the best case is still very bad.
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PaulK Member Posts: 17825 Joined: Member Rating: 2.2 |
The variability depends on the locus. Some genes vary more than others. IIRC some human genes associated with the immune system have well over 10,000 alleles. And humans have a relatively low genetic diversity.
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AdminBen Inactive Member |
3) Likewise in the Bible story of the Flood the inhabitants of the ark are supposed to be the sole survivors - again there are not other populations to consider. The effective human population under the usual interpretation, then, would be 5. "Unclean" species would be reduced to 2 individuals - a situation nearly as bad as the cheetah bottleneck (and even worse under some YEC interpretations, where multiple species would be descended from a mere 2 individuals living 4500 years ago). This is why YECs have to postulate a greater inbuilt genetic diversity in these few than we normally see these days. More genes for one trait for instance. To PaulK and Faith: This thread's going fast, and I'm very busy, so I don't have time to figure out who brought up what. So sorry in advance; I chose this post because it's the most recent as I'm checking now. This thread is about data, not postulates. If people see data that suggsets something, let's talk about the data and how it fits into current scientific theory. There's no need to talk about any "postulates" or bible stories here. Thanks. This message has been edited by AdminBen, Tuesday, 2005/09/27 09:06 AM Comments on moderation procedures (or wish to respond to admin messages)? - Go to:
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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
The variability depends on the locus. Some genes vary more than others. IIRC some human genes associated with the immune system have well over 10,000 alleles. And humans have a relatively low genetic diversity. THIS is what I've been supposing but haven't known for sure. Thank you very much. THAT MANY alleles for one gene??? But that would depend on the number of individuals wouldn't it? That is, thinking of Noah and family, or his three sons and three daughters-in-law, who are the parents of all the rest of us, does that mean that they are limited to a maximum of 12 alleles for a particular gene among them or am I misunderstanding something?
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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
OK Ben.
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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
No, you are wrong to say that the cheetah's ahven't recovered their genetic variability. Partly thanks ot more recent - but less severe - bottlenecks the cheetahs are still suffering the effects but their variability has recovered to some extent. Can you describe this at the gene level? And has mutation been observed to be the cause of the increase?
Postulating greater genetic variability is not much help. Even the best case is still very bad. That is what I would assume. Recovering genetic variability to the point that the cheetah is no longer threatened with extinction is just about impossible. This message has been edited by Faith, 09-27-2005 12:15 PM
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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
No, you are wrong to say that the cheetah's ahven't recovered their genetic variability. Partly thanks ot more recent - but less severe - bottlenecks the cheetahs are still suffering the effects but their variability has recovered to some extent. Oops, I think I misread this the first time around. Now it appears you are saying that more recent bottlenecks have increased their variability? But this can't be so. A bottleneck always reduces genetic variability.
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PaulK Member Posts: 17825 Joined: Member Rating: 2.2 |
For noah's familiy without mutations the sons would have no genes that weren't presnet in their father or their mother. Assuming a single mother (as seems to be typical) that's an effective population of 5. So you're down to 10 possible variants for each gene. At most.
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AdminBen Inactive Member |
Faith,
First off, I wanted to apologize up front for having to address admin issues twice in the same morning. If I had more time, and if this thread was going a little slower, I could have been more careful. I'm struggling to keep up. So, I apologize for posting twice, that may be discouraging. Nonetheless, the issues I see are really important to me, and I want to be REALLY clear and consistent with these things. So please bear with me and look through the two issues I'm bringing up below: First, I think you're really starting to approach things from a YEC perspective. That can't happen here. I saw this a bit in the post I brought up before, but there are two more posts that I ran across that made me really feel that things are moving in the wrong direction: http://< !--UB EvC Forum: Some mutations sound too good to be true -->http://EvC Forum: Some mutations sound too good to be truehttp://< !--UB EvC Forum: Some mutations sound too good to be true -->http://EvC Forum: Some mutations sound too good to be true As usual, I will run on about why this is critical: In the future, YECs may be able to come up with a set of postulates or theorems that explain all scientific data and also are consistent with the Bible. There are no such set of postulates. Furthermore, even if that happens, current scientific theory is not invalidated in any way--only new observations can do that. All that will provide is a vialbe alternative. The point is, all discussion here is whether or not current scientific theory can explain all of the current empirical evidence and, if so, how? Discussing alternative frameworks is outside of the scope of this thread. I was disappointed to see that you're starting to use this thread as a way to think about alternative hypotheses. Your job, in this thread, is exactly what I said above: to discuss whether or not current scientific theory can explain all of the current empirical evidence and, if so, how. In these threads, current scientific theory stands, or falls, on it's own. We're going to use OTHER threads to discuss alternative approaches. Second, I'm also becoming worried about the way you're wording things and how you're thinking about things here: http://< !--UB EvC Forum: Some mutations sound too good to be true -->http://EvC Forum: Some mutations sound too good to be true
You are claiming that mutation alone increases genetic variability but only over great great periods of time -- in 10,000 years it has not rescued the cheetah It is OK to use words to distance yourself from this "claim", because you feel there is an inconsistency (that you describe lower in the post). The inconsistency is based on two pieces of data and / or scientific theory. This is a good, logical approach in my eyes.
and you consider 10,000 years to be a small period of time When discussing science, we ALL consider 10,000 years to be a small period of time. There are no young earth thinkers in science. To honestly think through the science, Faith, you have to reason using the conclusions found by science. By distancing yourself from this conclusion, you're moving away from scientific discussion (in my eyes). When we discuss science, we ALL use the same basic conclusions (theories). Even if it has to be an "intellectual game" for you, you need to do this. It may seem nitpicky, but even if I'm in some way wrong, it's important: this is one of the ways I've seen things move quickly away from scientific discussion and into verbal wars about young-earth vs. old-earth. And I know that's the last thing any of us want--more pointless verbal wars. It really does take a high level of vigilence in the words that are written. But it is critically important. Faith, please address any inquiries / comments about the contents of this post to the "General discussion..." thread linked below. We can talk about any of this there. Thanks. Comments on moderation procedures (or wish to respond to admin messages)? - Go to:
General discussion of moderation procedures Thread Reopen Requests Considerations of topic promotions from the "Proposed New Topics" forum New Members should start HERE to get an understanding of what makes great posts. Other useful links:
Forum Guidelines, Style Guides for EvC and Assistance w/ Forum Formatting
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PaulK Member Posts: 17825 Joined: Member Rating: 2.2 |
That's not quite correct. I'm saying that more recent bottlenecks have inhibited the recovery. (As a matter of simple logic the more recent bottlenecks would have had little effect unless genetic diversity were recovering)
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Wounded King Member Posts: 4149 From: Cincinnati, Ohio, USA Joined: |
The flavobacterium mutation that produced the nylon bug was a frame shift. This is somewhat of an exaggeration in a couple of ways. Firstly the enzyme covered in the frameshift paper (Ohno, 1984) is only one of three on the plasmid conferring nylon digesting abilitites, although all three are not required. Secondly the paper only shows that there is a possible long Open Reading Frame which can be produced by a hypothetical reverse frame shift mutation. There is no actual ancestral pre-mutation sequence which has been identified allowing a comparison. If this particular topic interests you there is another thread on it here. TTFN, WK This message has been edited by Wounded King, 09-27-2005 01:44 PM
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nator Member (Idle past 2192 days) Posts: 12961 From: Ann Arbor Joined: |
quote: Is my lack of bottom wisdom teeth deleterious?
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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
That's not quite correct. I'm saying that more recent bottlenecks have inhibited the recovery. (As a matter of simple logic the more recent bottlenecks would have had little effect unless genetic diversity were recovering) OK, I get it now. Somehow it looked ambiguous on second reading, but I see my error now. But not ALL their genes were fixed, so how is their having some effects from more recent bottlenecks a proof that they had recovered diversity -- as opposed to losing what little they still had?
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Faith  Suspended Member (Idle past 1466 days) Posts: 35298 From: Nevada, USA Joined: |
Is my lack of bottom wisdom teeth deleterious? I tend to think of anything's being missing as a negative effect of mutation, don't you? But of course under some circumstances it can confer a benefit, and in this case it appears to be neutral as far as consequences go.
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PaulK Member Posts: 17825 Joined: Member Rating: 2.2 |
quote: Having tried to check my memory it appears that I was in error. The highest number I have found is 1300.
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