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Author Topic:   Macroevolution: Its all around us...
PaulK
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Posts: 17825
Joined: 01-10-2003
Member Rating: 2.2


Message 96 of 306 (207824)
05-13-2005 3:12 PM
Reply to: Message 93 by quig23
05-13-2005 2:43 PM


Re: You are not very informed sir
Let;s make Schraf's question more clear.
What MEASURE of information are you using ?
How would we quantify information so we could tell if a change was an increase or decrease ?

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 Message 93 by quig23, posted 05-13-2005 2:43 PM quig23 has not replied

PaulK
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Posts: 17825
Joined: 01-10-2003
Member Rating: 2.2


Message 243 of 306 (218968)
06-23-2005 12:16 PM
Reply to: Message 241 by Wounded King
06-23-2005 12:00 PM


Re: Relevance?
Thinking about what has been written it seems to me that the effect would depend on:
1) The location of the microsatellites - if the locations in 2 species were not very close they would affect different regions of DNA
2) The proportion of mutations that occur within "rnage" of the microsatellites. If this is small then there will be little effect.
Any comments ? I'd appreciate some sort of quantititive estimates of the relevant factors (even if I am wrong about what they are !)

This message is a reply to:
 Message 241 by Wounded King, posted 06-23-2005 12:00 PM Wounded King has replied

Replies to this message:
 Message 244 by Wounded King, posted 06-23-2005 12:40 PM PaulK has replied

PaulK
Member
Posts: 17825
Joined: 01-10-2003
Member Rating: 2.2


Message 247 of 306 (218990)
06-23-2005 1:06 PM
Reply to: Message 244 by Wounded King
06-23-2005 12:40 PM


Re: Relevance?
Thsi quote is from the paper
In conclusion, previous studies of microsatellite flanking sequences have identified several features, including a tendency to harbour other microsatellites, a locally increased mutation rate, and, conversely, conservation over unexpectedly large tracts of evolutionary time. Our analyses support all these trends and provide a possible resolution for the apparent contradiction between faster evolution but at the same time greater sequence conservation.
My impressions are as follows:
The biggest effect appears to be an overall trend towards conservation of sequences - so differences would tend to be preserved rather than being overwhelmed by "convergent" changes.
Given that the microsatellite placement (and the sequence of the microsatellite itself) would have to be similar for genuine convergence. I don't see much room for significant convergence between organisms that were not already very similar genetically. Species might tend to stay "in step" after an evolutionary branchpoint but that should just cause the branchpoint to be placed a little later than it actually occurred.
(Added in edit)
And since it seems to be non-coding DNA any effects will be limited to recent divergences because non-coding DNA is not sufficiently conserved to be used in the study of anything else
This message has been edited by PaulK, 06-23-2005 02:36 PM

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