Are all Mutations harmful because creatures were designed?

Most mutations are neutral..Some mutations are beneficial, although they might not show up as beneficial until they are in the right environment.For example, people with a mutation for called 'delta 26' are resistant to aids. People with a double dose of it appear to be immune to the aids virus.Mind you, it's a rare mutation, and before HIV started being spread in the population, it was totally neutral.. it neither helped nor hindered someone's survival chances.Now, particularly in africa, this particular gene mutation has a benefit.

Delta 26... which aids for resistance against the HIV virus.There is a mutation in an Italian family that has a particularly dense High density Cholesteral. This particular mutation casuses the HDL to be particuarly effective against scraping plaque away from aterial walls. Individuals with this mutatition do not get hardening of the arteries, no matter poor their diet is. (google Apolipoprotein AI)

I couldn't find any articles on the Delta 26.. but I found plenty of articles on the Delta 32 genehttp://biology.plosjournals.org/perlserv/?request=get-doc...\http://ib.berkeley.edu/...mbre/GalvaniNovembreMicInf2005.pdfReappraisal of the historical selective pressures for the CCR5-32 mutation | Journal of Medical Genetics