How do you define the word Evolution?

Before mutations: 100% brown allele After mutations: 10% black fur, 90% brown fur You are saying that after the mutations there is less genetic diversity?

And ... black is dominant ... so, the Hardy-Weinberg equation gives us:

p^² + 2pq + q^²

where p is one allele and q the other allele, so pq is heterozygous and the others are homozygous,

The equation with {br} = 0.9 (making {BL} = .01) is

(0.9)^² + 2(0.9)(0.1) + (0.1)^²
= 0.81 + 0.18 + 0.01

and 81% are tan (homozygous) while 19% are black (1% homozygous and 18% heterozygous)

and ~1 in 5 mice can utilize the lava bed habitat, and of those ~1 in 4 offspring will be tan and need to escape back to the tan soil habitat.

Enjoy

RAZD writes: And ... black is dominant ... so, the Hardy-Weinberg equation gives us:

That was more of a guesstimate. The actual number is probably a bit lower since the black basalt outcroppings make up a small percentage of their overall range.

Edited by Taq, : No reason given.

So 90% of statistics used in arguments are made up on the spot?

RAZD writes: So 90% of statistics used in arguments are made up on the spot?

Not all. At the Uni I'm involved in around 80% of all the students who start studying Chemistry 1 don't even get basic degrees at the end. That's been relatively constant for around 100 years. So, when I look at the first year fresh faces trying chemistry 1 on the first day, I can tell them that around 80% of them won't ever get a degree. I ask them to study, study, study and change the stats.

Stats are not always useless. It just prepares people for reality.

Edited by Pressie, : No reason given.

"In the laboratory mouse, loss-of-function mutations at Mc1r are recessive and result in light color, whereas gain-of-function alleles are dominant and result in dark color (16)."

I was talking about loss of function between the MC1R gene and the agouti-signaling protein.
They are talking gain/loss of function as it relates to coat colour..
Dominant/recessive does not determine gain/loss of functional information. A normal light switch can be turned on or off. A broken light switch can result in a light permanently on (dominant) or permanently off (recessive); but the switch is broken in either case. Similarly with the MC1R gene.

Edited by CRR, : Changed subtitle

and ~1 in 5 mice can utilize the lava bed habitat, and of those ~1 in 4 offspring will be tan and need to escape back to the tan soil habitat.

They probably should be considered as two separate populations with gene flow between them.

CRR writes: I was talking about loss of function between the MC1R gene and the agouti-signaling protein. They are talking gain/loss of function as it relates to coat colour.. Dominant/recessive does not determine gain/loss of functional information. A normal light switch can be turned on or off. A broken light switch can result in a light permanently on (dominant) or permanently off (recessive); but the switch is broken in either case. Similarly with the MC1R gene.

You are claiming that any change, no matter what it is, is a broken switch. That is just denial.

RAZD writes: So 90% of statistics used in arguments are made up on the spot?

+/- 1.8%. Don't forget the standard deviation.

And ... black is dominant ... so, the Hardy-Weinberg equation gives us:

The alleles should only be expected to be in Hardy-Weinberg equilibrium in the absence of selection. Since both phenotypes are under selection, it's not relevant. The proportions will depend on the extent of the habitats that select for each colour morph.

Guess I gots some readin to do.

Thanks

Same here. Like when I retire at the end of the year.

At many colleges and universities in the USA we have the Osher Lifelong Learning Institutes (OLLI) program for adults 50+. They draw on the members' own expertise for their own classes and special lectures, plus members get buy parking on campus and are usually able to audit the regular university courses. However, locally all the OLLI courses and lectures are during regular work hours, so you pretty much have to be retired to participate.

So I see auditing a population genetics course in my future ...

...we have the Osher Lifelong Learning Institutes (OLLI) program for adults 50+

Good program! I've lectured there perhaps 10 times over the years.

One of the main problems I'm faced with right now is ready access to research materials, given my work schedule. That will give me ready access to materials in the libraries.

So I see auditing a population genetics course in my future ...

I've been thinking of doing this too, especially as Brown University is a bicycle ride away and I could catch a lecture by Kenneth R. Miller.

Enjoy

caffeine writes: The alleles should only be expected to be in Hardy-Weinberg equilibrium in the absence of selection.

Not quite. The population will still be subject to the same selection forces even after it has adapted to the environment, however these will tend to stabilise the population rather than change it.

Since both phenotypes are under selection..

Both population groups will move towards equilibrium for their environment, which is why for H-W Equilibrium they should be considered as separate groups. However since the groups interact where the habitats meet there will also be gene flow between the two which will interfere with equilibrium being reached.

Edited by CRR, : Changed subtitle