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Author Topic:   LAVA - Lossy Adaptation Via (Natural Selection) of Alleles (Explained)
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 22 of 51 (526452)
09-27-2009 5:43 PM
Reply to: Message 18 by AChristianDarkly
09-27-2009 8:44 AM


Hi, ACD.
Welcome to EvC!
AChristianDarkly writes:
I do not even have high-school biology. (Passed math and science{physics and the like} in high school with A's, however. Also went and got me a degree - some more physics and math.) True enough. But I can read. And apart from the nitty-gritty of things like molecular biology, I can kind of limp along.
I have not read your horrifically long opening post completely yet. (I read 1000's of others from 1000's of other IDists and creationists, and I got A's in physics, math and biology all throughout highschool and college). True enough. And, apart from the nitty-gritty things like your term "BOB+," I can kind of limp along.
So, you think this is enough on which to start a discussion between us?
-----
AChristianDarkly writes:
And apart from the nitty-gritty of things like molecular biology, I can kind of limp along.
Curiously, the crux of your argument seems to be about the nitty-gritty of molecular biology, so aren't you here disqualifiying yourself from this very argument?

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 18 by AChristianDarkly, posted 09-27-2009 8:44 AM AChristianDarkly has not replied

  
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 23 of 51 (526455)
09-27-2009 6:57 PM
Reply to: Message 1 by AChristianDarkly
09-23-2009 11:55 AM


Hi, ACD.
Let me preface my remarks by saying that you're a idiot. And, like Dr A said, you're probably schizophrenic.
I'd like to provide you some general advice: parenthetical commentary on yourself and your viewpoints does not help an argument at all. It makes you appear defensive, unconfident, and, yes, schizonphrenic.
-----
ACD writes:
And I don't care about the smoking- statistics- is- 'science' thing. Until that was verified bio-chemically, it was simply a really good guess. A really strong possibility. An Hypothesis... Any practicing statistician ... would agree with that view - I've talked to actual 'University Professors' (tm). Stats is not about facts or absolutes, it is about degrees of strength. Only in the 'new' annals of 'science' is it used, solely by itself, as 'proof.'
This paragraph alone is good reason to discredit absolutely everything you wrote. It represents a fundamental flaw in your understanding of how science works and what science is.
Neither hypotheses nor theories are "proven": statistics is the only tool used by any science to demonstrate the accuracy of any hypothesis. The term "hypothesis test" is a statistical method, and a hypothesis that has "passed" enough of these statistical procedures is considered a theory.
The only difference between biology and physics is that, in physics, it's easier to get higher levels of significance and narrower confidence intervals than in biology due to the relative simplicity of particle or object systems, but it's still exactly the same technique. So, if you discredit statistics as a means to verify a theory, then you are discrediting all of the sciences, not just the Theory of Evolution.
-----
ACD writes:
I.e. saying that is 'looks as if ToE is true', is not science. ''Hey, we have five things we all think looks to show that ToE is true.'' That's nice. No proof for ToE, then it is HoE. (Hey, be damn glad buildings and airplanes are not designed in that fashion! Or cars. Or heart-lung machines. Or watches. Or condoms. Or...)
I am sick and tired of creationists conflating science with engineering. Designing something that works (engineering) is not the same as devising an explanation for how it works (science). Case in point is gunpowder: the ancients figured out how to use gunpowder in weapons back when they believed in four- or five-element alchemical processes to explain how it worked.
If you first learn how something works (via theoretica science), it becomes easier to apply it to make new technology. So, science is behind most modern engineering.
Now, it doesn't always happen that way, but it's becoming increasingly common to design technology based on theoretical science.
Many medicines are created based on clinical trials that showed positive results, without any idea as to what chemical mechanism causes them to work (especially psychiatric medicines, because the state of knowledge about the function of the human brain is still very primitive).
But, car engines, airplanes, light bulbs and computers were all invented after science developed theories to explain how certain chemical and physical processes work. Also in this category are conservation strategies and biological control programs (controlling pests with natural enemies), both of which are based on knowledge gleaned from ToE.
ToE is real science worthy of the term "theory," and it has technological applications, just as other sciences do. It's only your misunderstanding of it and of science in general that makes it seem so less "scientific" than other scientific topics.

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 1 by AChristianDarkly, posted 09-23-2009 11:55 AM AChristianDarkly has replied

Replies to this message:
 Message 25 by AChristianDarkly, posted 09-28-2009 12:56 PM Blue Jay has replied

  
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 29 of 51 (526598)
09-28-2009 2:28 PM
Reply to: Message 25 by AChristianDarkly
09-28-2009 12:56 PM


Hypothesis Testing
Hi, ACD.
Seriously, stop commentating! Just write your arguments and have some confidence that I will understand them without your help. Better yet, adopt a writing strategy that allows you to commentate in line with the rest of your writing so you don't have to interrupt yourself to get your points across. And, allusions to future comments are not helpful in any conceivable fashion.
The entire point of your reply could have been effectively conveyed in about four sentences.
-----
ACD writes:
Thank you for the first real reply. (Of course, I may be mistaken: perhaps you too are addicted to the use of a label-gun. Just a different model. If you reply, then we will see, will we not.)
Just so you know, we're in a forum called "Free for All": this is the forum where incomprehensible garbage is placed, and the moderators make very little attempt to regulate what people write in their posts. That's why nobody is going out of their way to take you seriously.
And, Brad McFall is a poster here at EvC whose posts are so grammatically contorted that each of his posts creates a new singularity in linguistic space. You can look him up with the "member search" function and read some of his posts to get an idea of the depth of the insult intended by comparing you to him.
-----
ACD writes:
(I never, once, talked about hypothesis {testing} in the statistical sense of the word. I use Hypothesis, exclusively, to mean un-proven idea. You know, what Theories are before they grow up.)
But, that is literally the only sense of the word that there is, ACD: that was the entire point of my last post. Statistics, science and logic all use the same definition.
If you want "hypothesis" to mean something other than that definition, then you are no longer talking about the same thing that science is talking about, and your argument is nothing more than a request to shift our semantic paradigms to match yours.
-----
ACD writes:
Imagine a right triangle: to the left top, is A:'smoking'. At the bottom right, is C:'cancer'. At the bottom left, is B:'biochemical pathway: specific chemicals found in cigarettes cause cancer in cells.'
Going from A, to B, to C, is science. Going from A to C, is bullpoopy: just like psychology: which uses that exact same excuse of wanna-be, statistical H-testing 'science' to 'prove' whatever nonsense 'theory' had been dreamed up this week: hey, gotta keep giving out them sheep-skins!
The alternative, should B be missing, is a complete listing of all possible alternatives. (And even then, you would have to make real sure you got them all. And you would have to qualify your results and conclusions in any case. There are rules to all this, you know.)
There is no B for ToE. ToE is invisible.
It is generally supposed that natural selection is the main driver for ToE. Supposed. The mechanism for ToE is not known. (Do you see the problem here?)
Yes, I very clearly see the problem. The problem is that you are completely wrong. Natural selection is not just supposed to be the mechanism, it has been shown to be one of the two mechanisms that are required for evolution to occur.
It cannot be stressed enough: the process by which the connection between smoking and cancer was uncovered is identical to the process by which the connection between natural selection and evolution was uncovered.
Here is a citation from the 1950's about the connection between lung cancer and smoking:
Breslow et al. (1954). Occupations and Cigarette Smoking as Factors in Lung Cancer. American Journal of Public Health and the Nations Health. 44(2): 171-181.
Here is the abstract:
quote:
This four-year study offers additional evidence tending to connect heavy cigarette smoking with cancer. In addition, it lists several occupations that seem to have some etiological relationship to the disease. They need further study, as it is suggested.
Nice and solid, proven stuff, isn't it? Nothing like that "statistical H-testing" crap that evolution depends on.
Here is an excerpt of the methodology:
quote:
Definitive study of whether an occupation or cigarette smoking is a causative factor in lung cancer requires that the incidence rate for the exposed group be determined. This rate is then compared with that of a control population, the most acceptable control being all the rest of the population from which the exposed group came. Assuming the same diagnostic and reporting standards for both groups, one may thus determine how the chance that a member of an exposed group will develop lung cancer compares with the chance that such a person would develop the disease if he were not a member of the exposed group. If the likelihood of developing lung cancer is substantially increased by being in the exposed group (e.g., a certain occupation) one may conclude that the exposure is a causative factor in the disease. The key to this analysis lies in determining comparative incidence rates for a suspect group and a control population.
To sum up: in order to test the hypothesis that smoking causes cancer, we should compare the incidence of cancer in smokers to the incidence of cancer in the population as a whole. Interestingly, no biochemical mechanism is proposed.
Yep, nothing like that "statistical H-testing" crap at all.
Also interestingly, by this time, natural selection and genetics were already well-known and well-documented, and the Hershey-Chase experiment that showed DNA's connection to this function was revealed two years earlier than the above study (1952).
It seems we've known the biochemical mechanism for evolution a lot longer than we've known the biochemical mechanism for lung cancer.
And, also interestingly, smoking is only known to increase the risk of developing lung cancer, not to cause it (less than 20% of smokers develop lung cancer), so you really don't have as strong or as certain a causative link as you think you do.
-----
ACD writes:
Oh yes. Let me inter-space my remarks with the following: You are a smucl{.
You can just write, "smuck," you know: there's no rule about name-calling. But, next time, you should probably write, "schmuck," just to avoid providing me with more ammo with which to insult your education level.
Edited by Bluejay, : Emphasis.

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 25 by AChristianDarkly, posted 09-28-2009 12:56 PM AChristianDarkly has replied

Replies to this message:
 Message 31 by subbie, posted 09-28-2009 2:34 PM Blue Jay has not replied
 Message 35 by AChristianDarkly, posted 09-29-2009 1:30 PM Blue Jay has not replied
 Message 37 by AChristianDarkly, posted 09-29-2009 1:37 PM Blue Jay has replied

  
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 30 of 51 (526599)
09-28-2009 2:33 PM
Reply to: Message 27 by Larni
09-28-2009 1:38 PM


Hi, Larni.
Larni writes:
Psychological research is very, very, very statistical in nature!
I suppose I contributed to that with my comment about psychology being less thoroughly understood than other sciences. If I was wrong, I can retract my statement: it probably should have been aimed at neurochemistry instead of psychology, anyway.

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 27 by Larni, posted 09-28-2009 1:38 PM Larni has replied

Replies to this message:
 Message 34 by Larni, posted 09-29-2009 1:30 PM Blue Jay has not replied

  
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 40 of 51 (526907)
09-29-2009 3:25 PM
Reply to: Message 37 by AChristianDarkly
09-29-2009 1:37 PM


Re: Ode to the B
Hi, ACD.
ACD writes:
oops! you would call that an Unshakable Obviously-Proven-To-Be-True Full-Blown Scientific Theory; sorry!)
No, I wouldn't. There is no such thing as "proof" in science. That's what I meant when I wrote, in Message 23:
Bluejay writes:
Neither hypotheses nor theories are "proven": statistics is the only tool used by any science to demonstrate the accuracy of any hypothesis. The term "hypothesis test" is a statistical method, and a hypothesis that has "passed" enough of these statistical procedures is considered a theory.
I thought for sure you should be able to keep up with a simple statement that I made: I mean, after all, you can keep up with all the voices inside your head, so how hard could one statement be, right? Well, I suppose I've learned my lesson.
So, just to be sure you caught it this time:
SCIENTIFIC THEORIES ARE NOT "PROVEN TO BE TRUE."
This includes evolution and gravity.
Perhaps now you would care to address my argument for what it is, rather than for what one of the voices in your head seems to think it is?
-----
ACD writes:
Sigh. Dude... you seem to miss the point about why B is required. It limits the possible explanations. Hence the biochemical thingy.
Then, by all means, provide for me the biochemical mechanism by which smoking causes cancer. You might be surprised to learn that this biochemical mechanism to which you allude is not actually known at this present time.
E.g., see Hu et al (2009). Toxicology Letters. 190(1): 23-31, which states, in the first sentence of the abstract:
quote:
Despite the significance of cigarette smoke for carcinogenesis, the molecular mechanisms that lead to increased susceptibility of human cancers are not well-understood.
...and proceeds to describe a correlative, hypothesis-testing statistical experimental study that Hu Yingchun and a swarm of co-authors did to find support from a transcriptome level for the theory that smoking increases the risk of cancer.
All science uses the same methodology, and no science ever proves anything true. The word "theory" does not mean what you purport it to mean: it refers to a largely successful hypothesis, not to a proven fact.
Once you realize that, your entire argument becomes meaningless.
-----
ACD writes:
Ok. My spelling sucks - I would be lost without Word. Hence the 'smuck' and not 'schmuck'. You got me there.
My "schizonphrenic" (Message 23) went completely under the radar, though.

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 37 by AChristianDarkly, posted 09-29-2009 1:37 PM AChristianDarkly has replied

Replies to this message:
 Message 41 by AChristianDarkly, posted 09-29-2009 5:20 PM Blue Jay has replied

  
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 43 of 51 (527015)
09-30-2009 2:32 AM
Reply to: Message 41 by AChristianDarkly
09-29-2009 5:20 PM


Re: Ode to the Bunny
Hi, ACD.
First off, don't edit posts after people have responded to them (unless the editing is specifically requested by the responder).
The reasons for this should be obvious.
-----
ACD writes:
Did I ever reject statistics?
Did I ever say you did?
-----
ACD writes:
Did I ever state that there is such a thing as 'absolute proof?'
Did I ever say you did?
-----
ACD writes:
The problem with label-gunning, is that you start to see what is not there, jackass.
For an example of this, please see the above-quoted material.
-----
ACD writes:
I am aware of the point you are trying to make.
How can you expect me to believe this when you're still spouting this crap:
ACD writes:
Cancer is somewhat well understood, yes? It is known that some kind of biochemical mechanism causes it, yes?
...Take a whole bunch of cell cultures: those you treat with carcinogens tend to get cancer. The others far less so. This is not an issue of degree, it is a question of causality.
But _more_ than that: cancer cells show certain types of damage. It kind of makes sense to the experts that certain chemicals can indeed cause those types of damage.
It makes sense. (REAL sense. Not imagined sense.)
Which is B. Which is my point. Is this getting through your evo-powered-brain-armor yet?
Nothing here is different from the way we do things in evolutionary biology, ACD. Please stop repeating this as if there is something profound here.
-----
ACD writes:
If you were to bother to go read a (good; just in case) textbook on stats, under the section on HT, you will notice them carping on and on about 'listing all the alternatives.'
B limits it down to one. Kind of. Until something better comes along. Such is science.
Uh... what is your point? Is it now your argument that I don’t understand what you meant by B?
Is it always going to be your first assumption that I am an incompetent cretin? Or are you eventually going to get around to acknowledging that I am, in fact, qualified to do science (which is, by the way, the reason I am doing science professionally)?
Get it? Sigh.
-----
ACD writes:
(A bit more bluntly then. ToE 'edits' DNA. This {general} editing process is _invisible_. Cannot be directly inferred.) {X} Unless you directly trace the action of ToE on the DNA. Aka BOB.
This is your big point? That no one has seen evolution happening?
Why did you not just write, "no one has seen evolution happening" in your OP, then? Could it be because, when you say it so directly, it sounds really stupid? Maybe that should have been a clue to you.
This may come as a shocker to you, but no one has ever seen any biochemical mechanism in action. This is because people can't see molecules. It doesn't stop us from studying quantum mechanics, so why should it stop us from studying evolution?
Have you heard about the lizards that developed a new organ in 36 years? (News article and source)
Evolution has been observed. End of story. You lose.
-----
{Added by Edit:
ACD writes:
...you can indeed setup experiments that prove this. Conclusively. Via hypothesis testing.
No, you cannot prove it. Stop saying that you can prove stuff with hypothesis testing. The best you can do is support your decision to not reject it. This point is crucial for you to get through your thick skull.}
Edited by Bluejay, : Addition.

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 41 by AChristianDarkly, posted 09-29-2009 5:20 PM AChristianDarkly has replied

Replies to this message:
 Message 44 by AChristianDarkly, posted 09-30-2009 1:17 PM Blue Jay has replied

  
Blue Jay
Member (Idle past 2729 days)
Posts: 2843
From: You couldn't pronounce it with your mouthparts
Joined: 02-04-2008


Message 47 of 51 (527332)
09-30-2009 10:27 PM
Reply to: Message 44 by AChristianDarkly
09-30-2009 1:17 PM


B
Hi, ACD.
You keep repeating "B" vs "no B," but you have not produced an example of a theory that does not have a "B."
You said B is an observable mechanism that links A and C, and you made a big deal about how carcinogenesis was a good example of this model, but have completely failed to distinguish carcinogenesis from evolutionary science. All you have succeeded in doing is whining that I haven't accepted your assertion that there is a difference.
And now, this has simply given way to pseudo-swearing and self-righteous indignation. But, there has still been nothing but whining assertions that ToE is "different" somehow, and that, because of this difference, it does not deserve to sit in the company of other things that we call "theories."
Man up and support your argument! It's not on me to make your argument work out.
Let me try once more, anyway, just because I happen to be extremely hopeful about the ability of people to understand reason.
-----
A-B-C. I've been trying to avoid this, because it's fine for illustrating mechanisms, but is an incredibly stupid model of theoretical science because it includes a non-essential factor. Let me explain:
Your A: smoking
Your B: some biochemical pathway.
Your C: cancer
This is linking a superficial "mechanism" (smoking) to an outcome (cancer) via an actual mechanism (the biochemical pathway). Smoking is not really involved: it is just the source of the actual agent in the action. The only thing the smoking does is make it easier for a scientist to find out where to search for the real action. So, the theoretical aspects of your "A-B-C" model encompass only the "B-C" part.
ToE is actually multiple "B-C" parts nested within one another.
"Mutations" are actually the outcomes ("C") of a number of known and documented biochemical pathways ("B") that act on the genome. Each of these pathways constitute their own theory or model system within the field of chemistry.
"Natural selection" is also a conglomeration of mechanisms ("B," not biochemical this time, though) with a common outcome ("C"): detriment to survival and/or reproduction.
The mutation portion of ToE can be characterized as A-B-C in the following way:
A: DNA transcription/replication
B: a mutational mechanism (e.g. free-radical chemistry)
C: new material
A-C is DNA transcription/replication creates new material. A-B-C is DNA transcription/replication creates new material via mutational mechanisms.
{AbE: I'm changing the above to:
A: mutational source (e.g., UV radiation)
B: mutational mechanism (e.g., converting T to C)
C: new material
A-C is "UV radiation causes new material." A-B-C is "UV radiation causes new material by converting thymine to cytosine."}
From there, natural selection takes over. It can also be characterized as A-B-C in the following way:
A: source of a selectional mechanism (e.g. a predator)
B: a selectional mechanism (e.g. predation)
C: death
A-C is predators cause prey to die. A-B-C is predators cause prey to die via predation.
Mutational mechanisms produce all the material for evolution. Selectional mechanisms prevent some (probably most) of the material from contributing to evolution.
ToE is most appropriately characterized as the integration of many theoretical/mechanistic pathways that perfectly fit your A-B-C model. But, like your smoking causes cancer idea, it began as a broader, more conceptual model focused on finite, observable things and lacking a mechanistic explanation. But, with the Modern Synthesis of genetics and evolution, ToE’s mechanistic roots were provided.
This is the same thing that I showed you with your carcinogenesis example: it started as a vague, correlative idea (e.g. smoking causes cancer, A-C), but was eventually linked with mechanistic explanations that fit the B between there.
The reason you think ToE is different from other theories, and therefore not a theory, is because there’s a lot more to it than you thought, and you didn’t account for all the complexity.
ToE, in truth, is many theories all in one. And, ToE has resulted in many other, new theories: e.g. Optimal Foraging Theory and Game-Theory Evolution, two very influential models in ecology.
Even if you follow through with your threat to ignore me because you feel I'm some ignorant child, hopefully this post will do some good for someone else who just happens to read it.
Edited by Bluejay, : Marked addition/correction

-Bluejay (a.k.a. Mantis, Thylacosmilus)
Darwin loves you.

This message is a reply to:
 Message 44 by AChristianDarkly, posted 09-30-2009 1:17 PM AChristianDarkly has not replied

  
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