What I mean is, the question about the origin of the universe usually precipitates from the question about the origin of life.
There is a huge gulf between them. Hugely different areas of research: one involves the most esoteric of physics the other chemistry.
Trying to bring the two together is something like worrying about the strong force in the nucleus when you are trying to explain how a wind up clock works.
Yes, everything has some relationship to everything else but if you arent' able to "chunk" things then all research or dicussion bogs down and wanders all over the map.
Orgin of life research can take as given the existance of a universe with the physics and chemistry that we see. Then it needs to explain how imperfect replicators can arise given that background. Without the existance of a world with a know set of physical laws there is nothing to discuss.
Evolution can take as given that imperfect self replicators exist. Without imperfect self-replicators there can be no biological evolution. The science is to explain what happens when you DO have those imperfect self-replicators.
The big bang is explicitly NOT the point of orgin of the universe. It was treated that way once upon a time but the research now wants to answer what conditions cause a "bang" so there had to be conditions "before".
Analogously: The selection of a computer and it's construction does not worry about the solid state physics within it's chips. It takes that as a given and goes from there.
You HAVE to do this all the time or you can't make any progress AT ALL.
Let someone know when you focussed your OP (or Ops)