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Author Topic:   A Prescribed Evolutionary Hypothesis
DaveScot
Inactive Member


Message 43 of 300 (317124)
06-02-2006 11:44 PM


Testing the semi-meiotic hypothesis
Hello Dr. Davison
Before we get started I want to remind you that I have chosen not to use my real name here and I ask that you honor the rules you agreed to when you registered here and not invade my privacy by revealing my real name.
In case you didn't read the registration agreement here is the relevant portion:
EvC Forum: Information
You agree, through your use of the EvC Forum, that you will not use it to post any material which is knowingly false and/or defamatory, inaccurate, abusive, vulgar, hateful, harassing, obscene, profane, sexually oriented, threatening, invasive of a person's privacy, or otherwise violative of any law.
Are you willing to abide by this?

Replies to this message:
 Message 44 by John A. Davison, posted 06-03-2006 6:37 AM DaveScot has replied
 Message 46 by John A. Davison, posted 06-03-2006 7:47 AM DaveScot has not replied

DaveScot
Inactive Member


Message 48 of 300 (317359)
06-03-2006 9:11 PM
Reply to: Message 44 by John A. Davison
06-03-2006 6:37 AM


Re: Testing the semi-meiotic hypothesis
Could you describe what's special about a frog heterozygous for chromosome reorganization and how exactly does one identify such a frog?
Edited by DaveScot, : No reason given.

This message is a reply to:
 Message 44 by John A. Davison, posted 06-03-2006 6:37 AM John A. Davison has replied

Replies to this message:
 Message 49 by John A. Davison, posted 06-03-2006 9:39 PM DaveScot has replied

DaveScot
Inactive Member


Message 50 of 300 (317398)
06-03-2006 10:45 PM
Reply to: Message 49 by John A. Davison
06-03-2006 9:39 PM


Re: Testing the semi-meiotic hypothesis
You only used the word "loop" one time in the manifesto and no mention was made that it is how to identify the test animals.
There is another difficulty with the sexual model when one considers chromosome restructuring. Consider a chromosome pair heterozygous for a paracentric inversion. A single cross-over within the inversion loop will lead to the formation of an acentric and a dicentric chromosome, while the same kind of cross-over occurring in a pericentric inversion heterozygote leads to two monocentric chromosomes each carrying a deficiency and a duplication. All such gametes can be expected to result in a lethal zygote (White 1973).
Shortly thereafter
Any hypothesis of organic evolution must stand in accord with the realities of cytogenetics.
and finally
I realize that the vast cytogenetic literature is beyond the scope of this essay. Accordingly, in light of the above, I place the burden of proof on the Darwinians by challenging them to present karyotypic, genetic, taxonomic, fossil, or any other kind of evidence indicating that true species, genera, families, or any of the higher taxonomic categories have ever been produced or can now be produced through the agency of sexual reproduction.
It appears we have two imaginary, unproven means of speciation at issue in the above; semi-meiosis and Darwinian. You seem to have declared that to settle the matter the Darwinians have to prove theirs works and if they cannot then yours must be the truth by default. That doesn't sound like the scientific method to me. Maybe I'm misunderstanding your challenge. Please explain.
You are the expert on the manifesto. It's helpful when you refer to your own work you would quote a page and paragraph and drop the snide remarks about classes I should take.
At any rate, you didn't define any methodology for finding these frogs that are heterozygous for chromosome reorganization. You say they can be identified by a loop structure evident during meiosis. So to find these frogs does one have to watch frog germ cells being created under a microscope with enough resolution to see this loop structure? And then what, when one of those germ cells is identified somehow take it off the slide and grow it into an adult frog?
Verification of this hypothesis necessarily requires someone to perform some work in a laboratory. I'm trying to determine what the work is and how it is to be performed. There's a reason no one has done this experimental work. I want to know if difficulty or impossibility is the reason. I don't believe for a New York minute that fear of exposing the Darwinian hoax is why no one has done this experimental work. The scientist who successfully disproves the modern synthesis and demonstrates the real mechanism of organic evolution would become rich and famous beyond his wildest dreams. That's something to covet not fear.
Edited by DaveScot, : Minor spelling corrections.

This message is a reply to:
 Message 49 by John A. Davison, posted 06-03-2006 9:39 PM John A. Davison has replied

Replies to this message:
 Message 52 by John A. Davison, posted 06-04-2006 7:02 AM DaveScot has replied

DaveScot
Inactive Member


Message 53 of 300 (317751)
06-04-2006 10:24 PM
Reply to: Message 52 by John A. Davison
06-04-2006 7:02 AM


Re: Testing the semi-meiotic hypothesis
Yes indeed one has to look under the microscope to observe the stages of meiosis.
Thank you for the clear answer. Here are some further questions:
Could you describe the procedure for observing a frog germ cell being created under sufficient resolution to identify it as heterozygous for a chromosome reorganization? Please provide enough detail so I can get an idea of the time and effort required per observation.
After finding one of the above, is there a way to recover it from the microscope stage and grow it into an adult frog? Again, if you could, provide enough detail so I can get an idea of the time and effort required.
Finally, do you have an estimate of how many observations might be necessary in order to find the one required?
DaveScot and I have been over all this many times before.
No we have not. The most I've gotten in the past is a description of the animal you needed and couldn't locate. Perhaps you discussed this further with someone else. If so I'd be happy to read that account of it and save you the trouble of repeating yourself. If you could be so kind as to give me a direct link to where this is recorded I shall go read it forthwith.
I have repeatedly explained what is required to be able to test the semi-meiotic hypothesis and even gone into detail on the methods involved, including how the SMH could be tested with mammals where chromosomal configurations are already well known.
I have never seen a detailed description of the experimental work including equipment, procedures, and estimates of the manpower required. I don't know about labs in academia but I spent decades in commercial research labs and writing up your experimental program before embarking on it is standard operating procedure just like a business plan is SOP before starting up a new line of business. Is it done differently in university laboratories?
It seems to me you're being rather evasive about this. I'm giving you the benefit of doubt that the semi-meiotic hypothesis has merit that warrants testing it. That appears to be more generous than most people are willing to be with it. I'm merely trying to determine what it would cost to test it. Research has to be paid for, Doctor Davison, and the people writing the checks to cover it usually want some idea of the cost and anticipated range of results before underwriting the program. I'm rather surprised you have never written up a detailed experimental program to submit to various sources for funding.

This message is a reply to:
 Message 52 by John A. Davison, posted 06-04-2006 7:02 AM John A. Davison has replied

Replies to this message:
 Message 57 by John A. Davison, posted 06-05-2006 6:20 AM DaveScot has replied

DaveScot
Inactive Member


Message 60 of 300 (317836)
06-05-2006 7:40 AM
Reply to: Message 57 by John A. Davison
06-05-2006 6:20 AM


Re: Testing the semi-meiotic hypothesis
You ask me to apologize for suggesting you're being evasive and then went on to avoid each and every question I asked. I'm sorry I suggested you were being evasive.
Here are the questions again.
Could you describe the procedure for observing a frog germ cell being created under sufficient resolution to identify it as heterozygous for a chromosome reorganization? Please provide enough detail so I can get an idea of the time and effort required per observation.
After finding one of the above, is there a way to recover it from the microscope stage and grow it into an adult frog? Again, if you could, provide enough detail so I can get an idea of the time and effort required.
Finally, do you have an estimate of how many observations might be necessary in order to find the one required?

This message is a reply to:
 Message 57 by John A. Davison, posted 06-05-2006 6:20 AM John A. Davison has replied

Replies to this message:
 Message 61 by John A. Davison, posted 06-05-2006 8:00 AM DaveScot has not replied
 Message 65 by John A. Davison, posted 06-05-2006 10:05 AM DaveScot has not replied

DaveScot
Inactive Member


Message 63 of 300 (317877)
06-05-2006 9:43 AM
Reply to: Message 62 by Admin
06-05-2006 8:41 AM


Re: Testing the semi-meiotic hypothesis
No need to ask me to leave. Doctor Davision has refused, as always, to provide details on an experimental program to test the prescribed evolutionary hypothesis and instead responds with hostility and evasion when asked. I have as a result come to the conclusion that it is simply another untestable narrative no better or worse than the Darwinian narrative of chance and necessity.
I might be naive about post-doctoral frog dissection but I'm certainly not naive about funding research for new ideas. In my professional career I participated in the evaluation of nearly a thousand requests in a $40 billion/year computer company to spend corporate money on research and development of patent abstracts and as a result I can smell a lame duck a mile away.
If anyone thinks I might be wrong just see if you can get Davison to describe an experimental program in enough detail so that someone with money and interest might be willing to fund it. Good luck and good bye.

This message is a reply to:
 Message 62 by Admin, posted 06-05-2006 8:41 AM Admin has not replied

Replies to this message:
 Message 66 by John A. Davison, posted 06-05-2006 3:16 PM DaveScot has not replied
 Message 67 by John A. Davison, posted 06-05-2006 5:47 PM DaveScot has replied

DaveScot
Inactive Member


Message 68 of 300 (318197)
06-06-2006 2:33 AM
Reply to: Message 67 by John A. Davison
06-05-2006 5:47 PM


Re: Testing the semi-meiotic hypothesis
Alrighty then. I was persuaded to endeavour to persevere.
Gynogenetic diploid amphibians are a standard research animal. You pulled a classic moving of the goalpost, Doctor Davison. We were talking about frogs heterozygous for chromosome rearrangment. That is the animal you said you needed and was not able to acquire. I was perfectly aware all along that frog eggs could be activated by piercing with a fine needle or using irradiated sperm to produce gynogenetic normal diploid adults. I'm not stupid and I read the manifesto more than once. These are not the same thing as heterozygous for chromosome rearrangement.
Now please could you describe with a modicum of detail how a frog heterozygous for chromosome rearrangement can be found? Before you lost the plot and went off on the gynogenetic tangent we were at the point where you said meiosis would have be observed under a microscope looking for a loop structure to confirm heterozygosity for chromosome rearrangement.
My questions then were (for the third time):
Could you describe the procedure for observing a frog germ cell being created under sufficient resolution to identify it as heterozygous for a chromosome reorganization? Please provide enough detail so I can get an idea of the time and effort required per observation.
After finding one of the above, is there a way to recover it from the microscope stage and grow it into an adult frog? Again, if you could, provide enough detail so I can get an idea of the time and effort required.
Finally, do you have an estimate of how many observations might be necessary in order to find the one required?
In answer to your question about what is meant by recovering it from a microscope stage: I presume you need live adult animals to work with. When it has been confirmed under the microscope that there was a loop structure during meiosis I had assumed you must then use that particular germ cell to produce an adult animal which will then be heterozygous for chromosome rearrangement. I was wondering how one recovers the cell from a microscope slide and raises it into an adult animal. The act of mounting it on a slide and illuminating it with a hot sub-stage light, possibly needing to stain it so you could see the detail, would kill it and make it impossible to then grow that particular germ cell into an adult. I'm not an expert at that kind of work so I'd asked you, the expert, politely and in straightforward manner how this would be done. Maybe I've got the procedure all wrong. I'm forced to guess at it because you're being uncooperative for some reason.
I take it that acquiring a frog heterozygous for chromosome rearrangement isn't easy or you would have done it yourself sometime since 1984. I am trying to determine how difficult a task it is and a ballpark cost. You seem determined to not provide me with the detail I'm requesting.

This message is a reply to:
 Message 67 by John A. Davison, posted 06-05-2006 5:47 PM John A. Davison has replied

Replies to this message:
 Message 69 by John A. Davison, posted 06-06-2006 7:12 AM DaveScot has replied

DaveScot
Inactive Member


Message 70 of 300 (318238)
06-06-2006 8:51 AM
Reply to: Message 69 by John A. Davison
06-06-2006 7:12 AM


Re: Testing the semi-meiotic hypothesis
Well then, if the mechanism of evolution isn't what you want to talk about I fail to see what there is to discuss. Billions of people reject the Darwinian narrative. You're just one more and given your hideous personality not exactly the top choice to discuss it with. The only thing different about you is that you have proposed an alternate mechanism. Since you don't want to talk about how that mechanism can be tested you're worse than useless. You're a liability to anyone who associates themselves with you because of your stinking rotten personality. See ya. Wouldn't wanna be ya.

This message is a reply to:
 Message 69 by John A. Davison, posted 06-06-2006 7:12 AM John A. Davison has replied

Replies to this message:
 Message 71 by John A. Davison, posted 06-06-2006 10:28 AM DaveScot has not replied
 Message 72 by Admin, posted 06-06-2006 1:05 PM DaveScot has not replied
 Message 73 by John A. Davison, posted 06-06-2006 9:55 PM DaveScot has not replied

DaveScot
Inactive Member


Message 134 of 300 (320471)
06-11-2006 11:37 AM


PEH
Doctor Davison
I'm as torn as ever between admiration/agreement with your published work and disgust/loathing of its author.
You've said on several occasions that your work speaks for itself. Sadly this is not true. You still speak for it. I'd like nothing more than to put your work back on Uncommon Descent and refer to it if it could somehow be dissociated with your foul living personality on the internet. As I indicated before, as great as your detective work and sound conclusions regarding the mystery of organic evolution, it becomes a liability to promote it as long as you are around to provide running commentary.
So here's what I'm going to do. I will restore your work at Uncommon Descent in memoriam if it is within my power at the time. Then it will truly be able to speak for itself. You told me many times that you'd have to die before your work is recognized. I didn't believe you at the time. Now I do. But how was I to know it was a self-fulfilling prophecy you were giving me.
{DaveScot's posting permissions in this forum have been terminated. - Adminnemooseus}
Edited by Adminnemooseus, : See above.

Replies to this message:
 Message 135 by John A. Davison, posted 06-11-2006 12:34 PM DaveScot has not replied
 Message 138 by John A. Davison, posted 06-11-2006 4:10 PM DaveScot has not replied
 Message 139 by John A. Davison, posted 06-11-2006 4:22 PM DaveScot has not replied

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