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Author Topic:   Questions on "Random" Mutations
Modulous
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Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 31 of 80 (410284)
07-14-2007 5:46 AM
Reply to: Message 24 by MartinV
07-14-2007 1:59 AM


Re: Dawkins about random mutation
Dawkins (there is no free access anymore to it, but the link to it's transcription is on the bottom of my post) took for granted that random mutation is responsible for dog's diversity.
Dawkins is well aware that dogs have a massive genetic diversity which was tapped into by humans through selective breeding. Dawkins states that this diversity came from mutation, before we started domestication (and obviously, to a lesser extent afterwards). The article you refer to can still be found here.
Someone asked him directly once about an experiment involving evolving fish and how quickly their colours changed. Dawkins said that the diversity was probably already there, rather than mutation occurring during the experiment. You can watch that here (Q & A session)
Edited by Modulous, : No reason given.

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 Message 24 by MartinV, posted 07-14-2007 1:59 AM MartinV has replied

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 Message 32 by MartinV, posted 07-14-2007 6:03 AM Modulous has replied

  
Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 33 of 80 (410287)
07-14-2007 6:15 AM
Reply to: Message 32 by MartinV
07-14-2007 6:03 AM


Re: Dawkins about random mutation
According Flegr this fact can be explained by a hypothesis that dogs evolved only recently, the other species are evolutionary older and frozen. So or so the case doesn't prove that alleles in dogs arouse by random mutation.
I have no idea what 'evolutionary older' means. I wasn't attempting to prove that the diversity arose by mutation, I was explaining Dawkins' position.
I was questioned also if there was any attempt to create new species by breeding throughout history.
Yes. Lots of times. Successfully.
Dogs are a good example. They are very diversified but they are the same species. Why using massive breeding many thousands years there are no descendant species?
We have to remember that aggressive artificial breeding reduces genetic diversity. Nevertheless - we do not know there are no descendant species. We'd have to go back 100,000 years and try and breed modern dogs with older dogs to see if they are still the same species.
Even if they could it wouldn't mean anything. Speciation isn't something that HAS to happen.
Because selection itself cannot create new species.
Exactly. Mutation is probably needed in almost all or all cases. The chromosomes have to stop recognizing each other so that germ cells cannot be produced.
So simple idea has to wait until midst 19 century to be discovered by former student of theology Darwin.
What is simple? That variation is required as well as the fact that nature can select? It is simple, but such is the way with science - it always looks simple in hindsight!
On my opinion natural selection just removes extremities and is purely conservative force.
Does anybody disagree? It is a force of keeping what works, a force that can lead to adaptation. It is certainly conservative whereas mutation is radical. The two combined...
Edited by Modulous, : No reason given.

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Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 52 of 80 (410737)
07-17-2007 2:19 AM
Reply to: Message 51 by MartinV
07-17-2007 12:47 AM


Re: Really BAD analogy.
My example is as ridiculous as Dawkins example of rowers in rowing-boats in Selfish gene.
Except that Dawkins managed to construct the metaphor in such a way that the rower teams would reproduce and the rowers (and their position) were heritable traits. It was intended to show that genes can benefit through selfish cooperation, and it worked.
You need to have replication and heritable traits in your example before it can have the same level of validity as this.

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 Message 51 by MartinV, posted 07-17-2007 12:47 AM MartinV has replied

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Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 57 of 80 (410840)
07-17-2007 1:47 PM
Reply to: Message 55 by MartinV
07-17-2007 1:09 PM


Re: Really BAD analogy.
First let us remind ourselves what Richard Dawkins said...Obviously it is Richard Dawkins not me who forgot on replication and heritable traits
You quoted the conclusion not the setup - did you think I wouldn't notice or something. The set up is as follows:
quote:
Suppose it is important in a really successful crew that the rowers should coordinate their activities by means of speech. Suppose further that, in the pool of oarsmen at the coach's disposal, some speak only English and some speak only German. The English are not consistently better or worse rowers than the Germans. But because of the importance of communication, a mixed crew will tend to win fewer races than either a pure English crew or a pure German crew.
The coach does not realize this. All he does is shuffle his men around, giving credit points to individuals in winning boats, marking down individuals in losing boats...What will emerge as the overall best crew will be one of the two stable states--pure English or pure German, but not mixed. Superficially, it looks as though the coach is selecting whole language groups as units. This is not what he is doing. He is selecting individual oarsmen for their apparent ability to win races... Selection at the low level of the single gene can give the impression of selection at some higher level.
So do we have replication? Yes. The 'genes' replicate in that the rowers are moved on into the next generation of boats. They are also shuffled (genetic recombination). The boats inherit the genes from the last race. The coach selects consistently winning individuals to be 'passed on' (he is natural selection in this analogy) and consistently losing individuals to not be passed on. By doing this he can construct a solid team without ever knowing that he is selecting based on language.
In the next generation "individual oarsman" will be in completely different team of oarsmen.
Yes - the shuffling of genes is more extreme than in nature, but the analogy is to show how the genes are being selected for their ability to work well with the other genes in the pool to produce a good team on average.
So each allele will be sitting in the next generation in almost completely different set of alleles (crew). Each individual (boat, crew) is unique genotyp. There are not the same genotypes - except true twins. There are always different phenotypes
At first - but since the coach is selecting his team some alleles will be on less teams and some will be on more teams as time goes on. Gene frequency, in the sense conveyed in the analogy, is shifting.
Because of this the effect of each individual allele will be different in each generation and each genotype. The effect of an allele depends predominantly on the mix of other alleles. The influence of an allele sitting in unique set of other different alleles to the phenotype and its fitness is always different.
Precisely! So an allele needs to be on a consistently winning team. If there are 10 English men and 4 Germans in the pool, the Germans will often be on teams with English men and so will often lose and get marked down, making them less likely to be picked for other teams in the future.
There is no doubt some alleles are detrimental and will be removed by NS. But other alleles and genes influence each other and the outcome depends on their mix which is in each generation different. Obviously there is no Dawkins hypothetical relation between an individual allele and fitness of the phenotype.
Dawkins puts forward the view point that genes that work together well to build better 'boats' or phenotypes will be selected for and increase in frequency.
Edited by Modulous, : No reason given.

This message is a reply to:
 Message 55 by MartinV, posted 07-17-2007 1:09 PM MartinV has replied

Replies to this message:
 Message 58 by MartinV, posted 07-17-2007 3:21 PM Modulous has replied

  
Modulous
Member
Posts: 7801
From: Manchester, UK
Joined: 05-01-2005


Message 60 of 80 (410891)
07-17-2007 5:51 PM
Reply to: Message 58 by MartinV
07-17-2007 3:21 PM


Re: Really BAD analogy.
We would have homozygous groups - all German or all English. Any mix would be detrimental. It is something we do not observe in the Nature
Yes, the point is that any mix would be detrimental. It was a quick example to show how ESSs concept allows us to see how a compatible combination of genes can appear to be selected for as a unit. If you had read the book you'd know that this is a simple example and real life examples drawing on the simple principles developed in the analogies are produced. His conclusion was that "well-integrated bodies exist because they are the product of an evolutionarily stable set of selfish genes". It is a furtherance of the idea he was building up to in the previous chapter and that he touched on his butterfly example in the earlier Chapter 3 (p31-32).
Either way - the example meets the requirements whereas your concept of programming languages doesn't.
Edited by Modulous, : No reason given.

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