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Author Topic:   Molecular Population Genetics and Diversity through Mutation
NoNukes
Inactive Member


(3)
Message 98 of 455 (785222)
05-30-2016 5:05 PM


Some pretty telling quotes from the Great Debate.
No commentary needed.
Faith writes:
To show an increase would require knowledge of its level in the past, and I don't trust DNA analysis to tell us that, the same way I don't trust the "fossil record" or radiometric dating to tell me how old the earth is -- because there's no way to test the test when it's about the unwitnessed past. And I can't trust somebody who's immersed in Evo assumptions to interpret things accurately either. Sorry.
And...
Genomicus writes:
Sure it is. These are all factors that contribute to the formation of new species.
Faith writes:
Yeah yeah yeah, why do you feel the need to repeat the party line which I've been at pains to divide into its relevant opposing activities because that's what makes my point? Anything to obscure my point perhaps? You don't have to like my way of dealing with the party line, but honesty should compel you to recognize the logic of it so you can follow my argument.
And...
As for bacteria, yeah, I don't trust bacteria, that's what it comes down to. I doubt that what can be learned from them can be meaningfully applied to mammals or other higher animals.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

  
NoNukes
Inactive Member


(1)
Message 99 of 455 (785226)
05-30-2016 10:10 PM


Faith on evidence
Faith writes:
My evidence that human genetic diversity has been decreasing is more a necessary deduction from my argument than direct evidence. However, I'd include the huge amount of junk DNA in the genome as evidence myself, which isn't likely to convince you of the point because you could only believe it's explained sufficiently by Evo Theory.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

  
NoNukes
Inactive Member


(1)
Message 101 of 455 (785267)
06-01-2016 4:15 PM


I do have this nagging question how it is that you can count on mutations at other chromosomal loci to keep up the genetic diversity while not affecting the collection of loci that determine the breed or species.
1) Possible responses:
Sheer numbers. There are a lot more loci that can vary without affect the species than are required to maintain whatever few traits distinguish species from their ancestors. So the probability is high that any particular loci will be unaffected by a random mutation. Plus the mutation rate is low anyway.
2) Species, unlike breeds, are not composed of homogeneous collections of critters. It turns out that not all black people look alike, have inherited the trait to pass on sickle cell anemia, lack persistent lactase intoleracne, not all Chinese people are identical, not all have creased eyelids, the same lactase intolerance, or the same enzyme balance.
As PaulK has expressed it, if a certain level of phenotypic variability exists in the parent group, and that group is a species, why is there some limit on how much variation we can add to a daughter species once speciation has ended.
3) The record already includes cited examples of variations among new species, and of variation in a single race of folks increasing over time. Your denials do not deal with the evidence and in fact your own proposition is contrary to the evidence and deserves little to no respect.
4) Say what?
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

  
NoNukes
Inactive Member


(1)
Message 103 of 455 (785275)
06-01-2016 9:38 PM
Reply to: Message 102 by 14174dm
06-01-2016 5:04 PM


Re: Was Adam Human?
If I understand Faith's proposal right, current humans have massive genetic depletion as evidenced by the "junk dna"
Exactly so. In short, Faith gives herself the right to speculate on the past based on her Biblical beliefs while denying others the right to evaluate even direct evidence from the past.
In this particular case, Faith has once again pushed an argument that she all but admitted she could not defend in a previous discussion. The last time she put forward the idea about genes dying off in the Flood I asked her how other people dying might affect Noah and his family's gametes and she admitted that her idea made no sense. Perhaps I will dig that up again.
It is pretty clear from her last couple of posts that Faith equates winning the debate with simply not ever being personally convinced that she is wrong.
ABE:
Here is that old admission Message 535 in response to Message 103
NN writes:
But the Flood loss could not represent any loss of function that Noah and his sons still possessed right? Surely those eight people possessed all of the vital functions for humans. Besides the silly notion that the people missing after the flood could have done something to the genes of living people, the flood itself could not have possible eliminated any essential human functions or else Noah and family would have had to be sickly.
Faith writes:
But that isn't what I thought. Really I hadn't thought it through at all, I just liked the idea, and when I finally did actually think it through I realized it wouldn't work. But what I sort of vaguely thought I thought was something like this: I thought the surviving eight, really the surviving three reproducing couples, had so little genetic diversity left (though they had enough to generate everyone living today, it's relative of course) that when later population splits occurred and some genes were reduced to fixed loci, that they'd become vulnerable to further loss and therefore keep adding to the junk DNA. But I finally realized that doesn't happen with population splits in general so there's no reason to expect it to happen as a result even of the Flood bottleneck. And as someone said here, it would only happen through mutations anyway.
Apparently no idea is too stupid not to have again.
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 102 by 14174dm, posted 06-01-2016 5:04 PM 14174dm has not replied

Replies to this message:
 Message 105 by Faith, posted 06-01-2016 10:46 PM NoNukes has replied

  
NoNukes
Inactive Member


Message 108 of 455 (785283)
06-02-2016 1:26 AM
Reply to: Message 105 by Faith
06-01-2016 10:46 PM


Re: Was Adam Human?
duplicate, but not my fault. I am getting 503 errors when I post.
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 105 by Faith, posted 06-01-2016 10:46 PM Faith has not replied

  
NoNukes
Inactive Member


(1)
Message 110 of 455 (785285)
06-02-2016 1:35 AM
Reply to: Message 105 by Faith
06-01-2016 10:46 PM


Re: Was Adam Human?
I did think it through and discovered it is defensible.
I don't think it is defensible and I suspect that you cannot defend it. But it would be easy to prove me wrong. Just answer the question I asked you before:
How does a bunch of folks passing away affect the gametes residing in other folks sitting in a boat? Why is that idea anything short of utterly ridiculous? Perhaps you owe Genomicus that explanation rather than me, but you are responding here.
At least when you are blaming stuff on the Fall, we can see where you are coming from, but here it appears that you think the genome some kind of spiritual connection linking members of a population instead of being simply particular genetic material that resides in an individual.
No, the idea is not defensible. It's just that you like the idea so much that you keep bringing it up. I was prepared to chalk your repetition up to your bad memory, but if you are now going to insist that you 'discovered' it to be defensible when you really cannot defend it, well that ain't honest.
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 105 by Faith, posted 06-01-2016 10:46 PM Faith has replied

Replies to this message:
 Message 111 by Faith, posted 06-02-2016 5:03 AM NoNukes has replied

  
NoNukes
Inactive Member


Message 112 of 455 (785294)
06-02-2016 5:37 AM
Reply to: Message 111 by Faith
06-02-2016 5:03 AM


Re: junk DNA a sort of fossil record of former life
It affects the living people by wiping out ALL the alleles for a great number of genes, in some cases leaving those few survivors on the ark with many homozygous loci and no opportunities to make them heterozygous; so as those are passed on down the centuries, and people divided into races, they are vulnerable to incompatible combinations and mutations that eventually kill the genes.
Loci dying out because they cannot find a mate? Do you understand that everyone has their own loci and that what you are talking about makes no sense? Mutations might cause loci to disappear, but not some allelle pining away for a missing opportunity to become hereozygous.
Of course there would be even more chances for 'incompatible combinations with more alleles available, which causes the whole 'Flood caused it' thing to fall apart. And if the answer is of course mutations, that answer is very curious. Because those mutations do not seem to have prevented the formation of races, nor does recombination appear to have resulted in non infer fertile races.
I think this proposition of yours created more problems than it addresses. PaulK has pointed out one them, but overall I doubt that there is any science based reason to believe any of this.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 111 by Faith, posted 06-02-2016 5:03 AM Faith has not replied

  
NoNukes
Inactive Member


(1)
Message 117 of 455 (785334)
06-02-2016 3:56 PM
Reply to: Message 115 by Faith
06-02-2016 9:45 AM


Is lightning evidence of Thor?
it just seems the most likely explanation of junk DNA from the YEC point of view. Perhaps you could try thinking like a YEC for a moment, maybe you'd come up with the explanation.
I believe this kind of reasoning to be flawed. Even if this was the natural and undeniable conclusion of either your beliefs or your 'theory', it is useless in a debate other than as a target to verify some prediction made on that basis. Junk DNA is not something predicted from your theory, it is instead something you've incorporated.
I totally agree that a YEC, particularly one without any particular knowledge of genetics might come up with a similar theory, and then be unable to reject the idea because of lack of awareness of what contrary evidence exists. But isn't that a useless excercise? How does the fact that you can make up a story about something evidence?

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 115 by Faith, posted 06-02-2016 9:45 AM Faith has replied

Replies to this message:
 Message 118 by Faith, posted 06-03-2016 12:00 AM NoNukes has replied

  
NoNukes
Inactive Member


Message 120 of 455 (785345)
06-03-2016 12:54 AM
Reply to: Message 118 by Faith
06-03-2016 12:00 AM


Re: We know about lightning, we don't know much about noncoding DNA
Who said it's "evidence?" I merely present it as a hypothesis that fits the Biblical Flood, and the Biblical Fall for that matter,
Uh, Faith, please...
You said it was evidence in the Great Debate thread. You did acknowledge that Genomicus would not accept it as evidence. If you agree that it is merely your hypothesis or proposal, then we agree, but that does not change the fact that called it evidence.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 118 by Faith, posted 06-03-2016 12:00 AM Faith has replied

Replies to this message:
 Message 121 by Faith, posted 06-03-2016 1:12 AM NoNukes has replied

  
NoNukes
Inactive Member


Message 122 of 455 (785349)
06-03-2016 1:35 AM
Reply to: Message 121 by Faith
06-03-2016 1:12 AM


Re: We know about lightning, we don't know much about noncoding DNA
You're right, I did call it evidence, but you seem to be making too much of that word.
Really? Given the requirement for evidence as support of argument in the science forum, I would think that evidence is of high importance.
It's like the fossil record and the strata are evidence for the Flood, it's a general compatibility between the observed physical facts and the Biblical revelation.
In short then, not only in junk dna not evidence for your position, but neither are the fossil record or the geological column evidence for the flood. Instead those things just fit your narrative regarding say, the grand canyon, said feature having zero mention in the Bible.
Is this really what you meant to convey? I think some of these things would be a surprise to regular participants.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 121 by Faith, posted 06-03-2016 1:12 AM Faith has replied

Replies to this message:
 Message 128 by Faith, posted 06-03-2016 5:25 AM NoNukes has replied

  
NoNukes
Inactive Member


Message 126 of 455 (785353)
06-03-2016 2:43 AM
Reply to: Message 124 by Faith
06-03-2016 1:52 AM


Finally.
Faith writes:
And when you start out saying we need to explain "new genotypes," my answer is that there shouldn't be any new genotypes anywhere in the evolution of a Kind.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 124 by Faith, posted 06-03-2016 1:52 AM Faith has replied

Replies to this message:
 Message 127 by Faith, posted 06-03-2016 5:05 AM NoNukes has replied

  
NoNukes
Inactive Member


(1)
Message 134 of 455 (785367)
06-03-2016 10:30 AM
Reply to: Message 128 by Faith
06-03-2016 5:25 AM


Re: We know about lightning, we don't know much about noncoding DNA
I sometimes think you must inhabit some other universe.
Not so fast, Ms. Faith.
Oh but they are, in the general sense I said. Dead DNA great evidence for the Fall, which brought death into the world and was punished by the Flood; fossils and strata great evidence for the Flood.
As you have acknowledged, those things are evidence in the fairly useless sense that the are 'generally compatible' with the narrative you push.
But not in the sense in which we all mean evidence. And not in the sense in which you know I meant when you asked who called them evidence, and when you insisted that I was making too much of that word. The sense in which they are facts, which if proven true, separate your proposition from the other propositions on the table.
It is absurd to have to explain something as obvious as the attempt by creationists to show the physical evidence in the world that supports the Bible.
You aren't explaining anything. What you are doing is completing the confirmation that you don't have any real evidence. Again, that some fact "supports the Bible" is an extremely low standard. That is particularly true when we are discussing propositions that you have made up after finding out the facts.
The billions of dead things found in the strata are superb evidence for the Flood.
Again, as you have already acknowledged, and as you point out here, evidence as you use the term means only 'generally compatible". The Bible says the flood killed lots of things, and there are fossils of lots of dead things. However once we get into the details we find that the structure, order, etc of the fossils reflects exactly what evolution predicts, and does not reflect the flood.
Similarly, your description of junk DNA does not either 1) separate your propositions from evolution. Both are equally compatible or 2) explain the detailed make up of junk DNA. In fact, you have to be told the nature of DNA before you make up the next element to your narrative to explain it. Why after such an exercise would it be amazing that your story matches the facts. You made it up after the fact.
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 128 by Faith, posted 06-03-2016 5:25 AM Faith has not replied

  
NoNukes
Inactive Member


Message 135 of 455 (785368)
06-03-2016 11:55 AM
Reply to: Message 127 by Faith
06-03-2016 5:05 AM


Re: Finally.
I don't know what your problem is, so I'll just ask how you expect to get something other than the BB's, bb's and Bb's of a particular genotype in the process of microevolution.
Why are you defensive? I quoted your remarks without any comment. One way to get something different is to have an imperfect copy of either the B or the b. That would be a mutation.
But of course you knew that given that the issue here is your denial of the role of mutations. So what was the point of your question?

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 127 by Faith, posted 06-03-2016 5:05 AM Faith has not replied

  
NoNukes
Inactive Member


(1)
Message 137 of 455 (785380)
06-03-2016 8:57 PM
Reply to: Message 136 by Faith
06-03-2016 7:38 PM


Re: You are looking at the wrong part of the system
Remember again that evolution itself has been defined as nothing more than a change in gene frequencies. That ought to show how much change you can get from nothing more than "shuffling alleles.
I think we all understand that you don't believe mutation is part of evolution. But the above quoted statement is not confirmation that the theory of evolution is in agreement with your proposal. Yes you can get changes in the population of phenotypes from generation to generation just by selection pressures and without any new variation. But that is not the same thing as claiming that no other factor is part of evolution.
I know you won't take the advice, but your presentation would likely be much stronger if you simply denied that the theory of evolution was correct than if you continue on the road of denying that the theory of evolution actually encompasses those things we can read in any biology text book. Your 'mutation destroys the species or the breed' is not cutting it.
Consider this, if a new dominate allele appeared that caused humans possessing it to become immune to HIV, or left handed, or to have creases in the back of their neck, would that mutation make a person non-Caucasian? If not, then how would such mutations ruin the breed/race if they occurred after the race formed? If so, then would this not be an example of a race becoming more diverse after formation? Can you really not make up your own similar examples?
As has been illustrated to you many times by direct quotes from origin of species, and also with quotes from modern sources, common descent requires much more than than your own proposal allows. The theory of evolution is that the source of variation includes mutations. Darwin is quoted as saying that without the source of variation, evolution would cease exactly as you have argued.
Beyond that, at this point between this thread and the Great Debate thread, examples of mutations fueling variation has been demonstrated with direct evidence. You of course are free to deny it. But your denials have zero basis.
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 136 by Faith, posted 06-03-2016 7:38 PM Faith has not replied

  
NoNukes
Inactive Member


Message 141 of 455 (785417)
06-04-2016 11:49 AM
Reply to: Message 139 by Faith
06-04-2016 7:48 AM


Re: You are looking at the wrong part of the system
here is probably more than just one gene involved for that trait too and you'll get different frequencies for each locus; but besides fur you've got new allele frequencies for EVERY trait of the animal, which is how you can get dramatic new dog breeds for instance.
This explanation is total crap. You get dog breeds by supplying intense selective pressure, namely by not allowing dogs who don't have most or all of the desired traits to remain in the gene pool. The point you have yet to address is that such selective pressures are extremely artificial and generally do not exist in nature. For example, the dark moths appear to have only minor differences from the white moths, and if we remove the predators, we would expect to see white moths increase in percentage.
It is also the case that dog breeders, in general do not simply start with a couple of animals with a trait and breed them together and then simply continue to breed their offspring. That they, of necessity bring in other animals during the breeding process in their attempt to eliminate recessive traits. What breeders accomplish simply does not happen naturally. And you have yet to successfully argue that it does.
If you get a very high frequency of an allele that was very rare in the parent population you could get a surprising new trait.
Could you? The evidence for this is what?
You don't need mutations, and if you got them they would only act the same way built-in alleles would act
Assuming that this statement is true, we would have to note that such things while acting the same as built-in alleles, would be an additional of variation, and diversity. So mathematically, and for the point of this debate, the result would not be the same.
Edited by NoNukes, : No reason given.

Under a government which imprisons any unjustly, the true place for a just man is also in prison. Thoreau: Civil Disobedience (1846)
History will have to record that the greatest tragedy of this period of social transition was not the strident clamor of the bad people, but the appalling silence of the good people. Martin Luther King
If there are no stupid questions, then what kind of questions do stupid people ask? Do they get smart just in time to ask questions? Scott Adams

This message is a reply to:
 Message 139 by Faith, posted 06-04-2016 7:48 AM Faith has not replied

  
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