Fructose vs. GlucoseThere are major differences in the human body breakdown of fructose and the more common simple sugar, glucose. Furctose must be converted by the liver into energy, fat, or glucose before it can be used by other organs. Conversely, Glucose is directally usable by virtually all tissues and organs and is the preffered energy source for the brain. Glucose and fructose breakdown in the liver both result in energy and fat production among other products. However, the glucose breakdown pathway is turned off when there is an accumulation of energy and fat, thereby preventing excess production. Fructose breakdown does not have this feedback mechanism, so energy and fat production depends solely on the presence of fructose. Therefore, a massive ingestion of fructose would result in an overwhelming production of energy and fat.
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