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Author Topic:   Can random mutations cause an increase in information in the genome?
SuperNintendo Chalmers
Member (Idle past 5862 days)
Posts: 772
From: Bartlett, IL, USA
Joined: 12-27-2005


Message 76 of 310 (286530)
02-14-2006 2:32 PM
Reply to: Message 68 by Garrett
02-14-2006 2:11 PM


You have no idea what you are talking about
Deoxyribonucleic acid (DNA) is a nucleic acid ”usually in the form of a double helix” that contains the genetic instructions specifying the biological development of all cellular forms of life (and most viruses).
You just don't know what you are talking about. You are attempting to use a layman's definition in a scientific discussion. Like I said, I'm no biologist but even I know that what DNA ACTUALLY does is code for protiens.
http://www.so.wustl.edu/...um/genetics/pdfs/ModGen_1D_SP.pdf
As to evolution being a fact...you are obviously referring to microevolution (ie. adaptation, natural selection) since macroevolution (ie. goo-to-you) is completely unrepeatable. You truly don't even understand my argument. Evolutionists like to remind you that microevolution is fact then suggest that proves macroevolution.
Macro and Micro evolution are the same things. They are simply HUMAN CONSTRUCTED TERMS to describe different degrees of the same process. It's certainly not a topic for this thread, but speciation has been observed. PERIOD. Until you understand the different between the process and the human constructed terms to describe said process you simply are not qualified to speak on the subject.
As to why a species can't acquire information...it's because no known natural process can create specified complexity. In other words, no unintelligent process would know how to arrange the strand in an order that had any meaning to the translator.
That makes no sense whatsoever. What is the translator? What is specified complexity? DNA codes proteins. This coding is transported by RNA if I remember correctly.
I can only imagine how ridiculous all this sounds to a real biologist.
Here's another way to think about it.... Do you know anything about computer programming? If so this may make sense.
DNA is like assembly language. It's written in the natural language of the processor. You could write any program using only assembly language (it would just take a LONG TIME).

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SuperNintendo Chalmers
Member (Idle past 5862 days)
Posts: 772
From: Bartlett, IL, USA
Joined: 12-27-2005


Message 77 of 310 (286531)
02-14-2006 2:36 PM
Reply to: Message 65 by randman
02-14-2006 2:02 PM


Re: Information Test
Hmmm...can you define "random" for us here so that we have precise definitions to work with?
Rand, would you accept this defintion?
A random number generator would be able to generate numbers (whole, rational, real, doesn't matter... just needs to be numbers of an infinite set) that had no relation whatsoever to the initial conditions of the generator. Of course it seems this would be impossible to build. It's certainly possible to build finite random number generators (dice are a great example)... but generators that operate on infinite sets of numbers are a whole other story.
Imagine a infinite sided DIE with a side for every natural number

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randman 
Suspended Member (Idle past 4927 days)
Posts: 6367
Joined: 05-26-2005


Message 78 of 310 (286534)
02-14-2006 2:39 PM
Reply to: Message 20 by Coragyps
02-14-2006 11:04 AM


new information
This is new information from the perspective of information in terms of design features although I am not sure it satisfies what garret is looking for.
one observation and one question
It's clear that in the evo models, natural selection is guided by pressure from the environment (and the local environment also guides the mutations we are learning. We also know the environment is formed from the actual physical make-up of the universe. In order to assert mutations are really random, you have to assert that the formation of the universe is random, and I think that's logically off the reservation. The universe itself exhibits rules, laws, order, etc,....what causes inanimate energy to order itself?
In biology, we say the organism's programming to survive (which to my mind is evidence of ID all on it's own), but what created the rules of matter and energy to be ordered by, and matter and energy itself?
I think the logical inference is an Intelligent Cause did, and so regardless of the mechanisms, whether evolution or direct creation, imo, it is all Intelligent Design because even in the evo model, the underlying guiding factor for life evolving are the physical (including QM), chemical, and environmental factors in place, and these things do not demonstrably have an origin in randmonness.
In other words, the random aspect is a massive assumption on the part of evos without any evidence or logic whatsoever. If, and this is a big if, life forms only through "naturalistic means", then that is still evidence of design because the design of the universe itself in it's origins dictates what designs can flow out of it.
And that still ignores the fact that so-called naturalistic means only hypothesis of evos is unproven and unlikely.

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Replies to this message:
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crashfrog
Member (Idle past 1495 days)
Posts: 19762
From: Silver Spring, MD
Joined: 03-20-2003


Message 79 of 310 (286536)
02-14-2006 2:45 PM
Reply to: Message 78 by randman
02-14-2006 2:39 PM


Re: new information
It's clear that in the evo models, natural selection is guided by pressure from the environment (and the local environment also guides the mutations we are learning. We also know the environment is formed from the actual physical make-up of the universe. In order to assert mutations are really random, you have to assert that the formation of the universe is random, and I think that's logically off the reservation. The universe itself exhibits rules, laws, order, etc,....what causes inanimate energy to order itself?
So, you don't accept randomness. Why not just come out and say that? How about pseudorandomness, like the random numbers generated by a computer? Can you accept that?
Would it satisfy you if we said that mutations were pseudorandom?
In other words, the random aspect is a massive assumption on the part of evos without any evidence or logic whatsoever.
Except that we detect that mutations are randomly distributed. Pseudorandomly, at least. (Pseudorandom numbers, for instance, would be strings of numbers that are deterministically generated but statistically indeterminable from a truly random sequence. By definition there's no way to distinguish a random sequence from a pseudorandom one after the fact.)

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 Message 78 by randman, posted 02-14-2006 2:39 PM randman has replied

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SuperNintendo Chalmers
Member (Idle past 5862 days)
Posts: 772
From: Bartlett, IL, USA
Joined: 12-27-2005


Message 80 of 310 (286540)
02-14-2006 2:49 PM
Reply to: Message 78 by randman
02-14-2006 2:39 PM


Good question Rand
It's clear that in the evo models, natural selection is guided by pressure from the environment (and the local environment also guides the mutations we are learning. We also know the environment is formed from the actual physical make-up of the universe. In order to assert mutations are really random, you have to assert that the formation of the universe is random, and I think that's logically off the reservation. The universe itself exhibits rules, laws, order, etc,....what causes inanimate energy to order itself?
In biology, we say the organism's programming to survive (which to my mind is evidence of ID all on it's own), but what created the rules of matter and energy to be ordered by, and matter and energy itself?
I think the logical inference is an Intelligent Cause did, and so regardless of the mechanisms, whether evolution or direct creation, imo, it is all Intelligent Design because even in the evo model, the underlying guiding factor for life evolving are the physical (including QM), chemical, and environmental factors in place, and these things do not demonstrably have an origin in randmonness.
In other words, the random aspect is a massive assumption on the part of evos without any evidence or logic whatsoever. If, and this is a big if, life forms only through "naturalistic means", then that is still evidence of design because the design of the universe itself in it's origins dictates what designs can flow out of it.
Randman, I think you actually bring up a good point here. Is mutation truly random? Well that depends on what definition of random you are using.
Scenario 1 = If a grand unifying Theory of physics exists and one could know the exact starting conditions in any scenario then nothing is truly random.
Scenario 2 = Either there is no grand unifying theory or it is impossible to ever know the exact starting conditions in any scenario.
Now, Son Goku or Cavediver may jump in here and shoot down my scenarios, but they seem to make sense to me. (they make us engineers concentrate on how to use these theories to design transistors, not why they exist!).
What is a good definition of random mutation? Here are some possibilities:
1. Mutations that the organism has no control over
2. Mutations that can no be predicted using any current methodologies.
I think we call the mutations random because we have no way to predict what they will be. I can expose organisms to radiation, but I have no way to predict what mutations might occur (I only know that if I expose a mild-mannered scientist to gamma radiation he will turn into a large angry green hulk.... hehehehehehe)
I think the whole concept of randomness might warrant an entire new thread.

This message is a reply to:
 Message 78 by randman, posted 02-14-2006 2:39 PM randman has replied

Replies to this message:
 Message 93 by randman, posted 02-14-2006 3:16 PM SuperNintendo Chalmers has replied

SuperNintendo Chalmers
Member (Idle past 5862 days)
Posts: 772
From: Bartlett, IL, USA
Joined: 12-27-2005


Message 81 of 310 (286541)
02-14-2006 2:51 PM
Reply to: Message 79 by crashfrog
02-14-2006 2:45 PM


Good definition
Except that we detect that mutations are randomly distributed. Pseudorandomly, at least. (Pseudorandom numbers, for instance, would be strings of numbers that are deterministically generated but statistically indeterminable from a truly random sequence. By definition there's no way to distinguish a random sequence from a pseudorandom one after the fact.)
I suggest we use crashfrog's definition of a random distribution. i.e. A distribution of items (numbers, values, whatever) that is mathematically indistinguishable from a truly random distribution. So whether it is truly random or not is irrelevant from our perspective.
Nice job Crash... that's exactly what I was trying to say!

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Replies to this message:
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randman 
Suspended Member (Idle past 4927 days)
Posts: 6367
Joined: 05-26-2005


Message 82 of 310 (286543)
02-14-2006 2:53 PM
Reply to: Message 79 by crashfrog
02-14-2006 2:45 PM


Re: new information
Can you define what "random" means? It's a basic concept within evolutionary theory, and yet it's not often evos can define it.

This message is a reply to:
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Replies to this message:
 Message 86 by SuperNintendo Chalmers, posted 02-14-2006 3:04 PM randman has replied
 Message 130 by crashfrog, posted 02-14-2006 7:06 PM randman has replied

Percy
Member
Posts: 22502
From: New Hampshire
Joined: 12-23-2000
Member Rating: 4.9


Message 83 of 310 (286544)
02-14-2006 2:53 PM
Reply to: Message 47 by randman
02-14-2006 12:50 PM


Re: logical?
randman writes:
Percy, but if that is it's own thread, then why are you diverting this thread bringing up God in the manner you are?
It seems you want to bring it up, and then say, but no one can answer back. If it's off-topic to consider the idea that God's life force for the universe can perhaps be detected and observed, then it's certainly off-topic to bring the matter up in the first place on a thread concerning random mutations.
I didn't bring up God, Garrett did. Since your initial premise is incorrect, your conclusions are also incorrect.
If you have further complaints about my conduct in this thread, please bring them to the [forum=-19] forum.
--Percy

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Jazzns
Member (Idle past 3940 days)
Posts: 2657
From: A Better America
Joined: 07-23-2004


Message 84 of 310 (286549)
02-14-2006 2:59 PM
Reply to: Message 65 by randman
02-14-2006 2:02 PM


Re: Information Test
Sure. Random by itself is hard to define because you have things like random sequences, or random events. In the case of mutation which is a random event a good definition would be an event that does not have a well defined generator. In the case of a random sequence I would say it is a sequence for which there can be no closed form for defining the sequence.

Of course, biblical creationists are committed to belief in God's written Word, the Bible, which forbids bearing false witness; --AIG (lest they forget)

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Garrett
Member (Idle past 6194 days)
Posts: 111
From: Dallas, TX
Joined: 02-10-2006


Message 85 of 310 (286550)
02-14-2006 3:01 PM
Reply to: Message 20 by Coragyps
02-14-2006 11:04 AM


I think this is another example of extra content, less meaning.
The information has been altered so that a different protein is created as a result. Although this has a beneficial effect, it is actually detrimental to the overall system function as a whole.
In terms of the sickle-cell scenario (GUA), the actual trigger that prevents malaria is the fact that the mutation causes the hemoglobin to form in the wrong shape and fail to carry oxygen. This lack of oxygen carrying efficiency is what causes many with the mutation to contract fatal anemia. The same oxygen deficiency, however, also resists Plasmodium. So it's a case of a breakdown of the system being beneficial in some regards. Following down this path would actually lead to more problems than benefits in the long run. I'm not as familiar with the AAA scenario, but suspect it's working right along the same lines.
Since the oxygen isn't able to act in it's normal capacity I would say the specified complexity has actually reduced in this case. Meaning, the biological entity in question has fewer functional process than before the "beneficial" mutation.

This message is a reply to:
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Replies to this message:
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SuperNintendo Chalmers
Member (Idle past 5862 days)
Posts: 772
From: Bartlett, IL, USA
Joined: 12-27-2005


Message 86 of 310 (286551)
02-14-2006 3:04 PM
Reply to: Message 82 by randman
02-14-2006 2:53 PM


definition
I think a good question to ask would be "are mutations generally benefical/detrimental/neutral". Of course one would then have to define what makes a mutation good or bad... but if it can be shown that beneficial mutations are statistically no more likely or even less likely than neutral or detrimental mutations then mutation is sufficiently random for the purposes of evolution.
I guess another question would be, "Is there any evidence that environmental factors influence the type of mutation". For example, if I live somewhere with no ozone layer are mutations that help protect me from ultraviolet rays more likely to occur (I know they are more likely to be SELECTED upon, but are they more likely to occur in the first place?). I'm pretty sure experments have shown this is not the case. But I would welcome the input of someone more knowledgable on the subject.

This message is a reply to:
 Message 82 by randman, posted 02-14-2006 2:53 PM randman has replied

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Jazzns
Member (Idle past 3940 days)
Posts: 2657
From: A Better America
Joined: 07-23-2004


Message 87 of 310 (286552)
02-14-2006 3:07 PM
Reply to: Message 66 by Garrett
02-14-2006 2:09 PM


Re: Creationist and their misuse of "information"
Please I am not trying to berate you. I am trying to be as straight forward as I can.
Your response is insufficent although I can respond in a way that makes it clearer what is needed.
You need a definition for whatever you want to call it (specified complexity, information, meaning, etc) such that you can then derive a metric from it.
You cannot say that one thing has more or less information unless you have a metric for calculating how much information the subject has.
This is important because right now this sentence:
Adding length, does not add specified complexity and meaning.
has no value without a metic and there is no way for you to show that this is true. With a metric you could then calculate the specified complexity of that phrase you used as an example. Then you could add the word 'lazy' like you did and independently check your metric. Then if the value you get out of your metric is the same you could say that there was no increase by the duplication.
Without that though all you are doing is basically typing gibberish using big words like 'specified complexity'.

Of course, biblical creationists are committed to belief in God's written Word, the Bible, which forbids bearing false witness; --AIG (lest they forget)

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SuperNintendo Chalmers
Member (Idle past 5862 days)
Posts: 772
From: Bartlett, IL, USA
Joined: 12-27-2005


Message 88 of 310 (286553)
02-14-2006 3:08 PM


A defintion I found
Evolution = NS(RM, OS)
where f is a non-trivial function, NS is natural selection and is not random, RM is random mutations and is random, and OS is other stuff, some random, and some that is not random.
That is, following Dawkins and many others, evolution is the non-random selection of random variation.
In probability theory, it is known that if X is a random variable, then for a non-trivial function f, f(X) is a random variable. Therefore, because evolution is a non-trivial function of variables, some of which are random, evolution is a random variable, and therefore it is correct to call it random.
To summarize, while evolution could reasonably be considered and described as biologically or practically non-random, it is technically, mathematically random. To say that calling evolution random is "the opposite of truth" and "false" could itself be viewed as the opposite of truth and false.
What do you guys think of this?
Source: Statisticool.com
The math makes sense to me.... So we can at least say it's "mathematically random".
Keep in mind that as crash alluded to earlier... mathematically random and truly random are slightly different concepts I think

randman 
Suspended Member (Idle past 4927 days)
Posts: 6367
Joined: 05-26-2005


Message 89 of 310 (286555)
02-14-2006 3:10 PM
Reply to: Message 86 by SuperNintendo Chalmers
02-14-2006 3:04 PM


Re: definition
I think adaptive mutations are considered by some as evidence they are more likely to occur in the first place, or that this can occur. One paper WK linked to proposed that quantum mechanics governed mutations and dealt with a possible information exchange, I believe, to cause adaptive mutations.

This message is a reply to:
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ramoss
Member (Idle past 640 days)
Posts: 3228
Joined: 08-11-2004


Message 90 of 310 (286556)
02-14-2006 3:10 PM
Reply to: Message 31 by Garrett
02-14-2006 11:55 AM


nteresting that you ask me to limit myself to the topic even as you don't limit yourself in that manner.
And believing in a supernatural God doesn't violate science, rather is totally consistent. Observable science tells us that our natural laws prohibit life from arising from non-life unassisted. Thus a supernatural first cause is logically needed.
There is no evidence your statement is correct. We are accumulating data that shows that a supernatural force is not required to have
primative life formed from organic chemicals in the proper environment.

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