Hi,
I don't have access to the literature right now, so could you explain what copy number variation is?
I am thinking microsats and duplicated genes, but perhaps i am on the wrong track.
[AbE] I know that microsatellites are the result of variation in copy number of nucleotide pairs, triplets, quadruplets, or whatever, and that the human population varies moderately in copy number. At a different order of magnitude, I know that duplicated genes might result in numerous copies of a protein-coding sequence, and that in this respect the human population is pretty constant in copy number. So I can only assume that the authors of the paper are talking about some intermediate level, perhaps variation in copy number of intronic elements or something like that?
Mick
Edited by mick, : No reason given.